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发表论文
2017
1.
Liu H., Saxena A., Sidhu S.S.*, and Wu D.H*. (2017) Fc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds. Front Immunol 8:38 doi: 10.3389/fimmu.2017.00038.

2.
Han Y.B., Chen L.Q., Li Z., Tan Y.M., Feng Y., and Yang G.Y. (2017) Structural insights into the broad substrate specificity of a novel Endo-glycoceramidase I belonging to a new subfamily of GH5 glycosidase. J Biol Chem doi: 10.1074/jbc.M116.763821.

2016
1.
Saxena A and Wu D.H*. (2016) Advances in Therapeutic Fc Engineering – Modulation of IgG-Associated Effector Functions and Serum Half-life. Front. Immunol. 7:580. doi: 10.3389/fimmu.2016.00580

2.
Liu J. and Shui S.L. (2016) Delivery methods for site-specific nucleases: Achieving the full potential of therapeutic gene editing. J Control Release 244(Pt A):83-97 doi: 10.1016/j.jconrel.2016.11.014.

3.
Scattolini V., Luni C., Zambon A., Galvanin S., Gagliano O., Ciubotaru C.D., Avogaro A., Mammano F., Elvassore N., and Fadini G.P. (2016) Simvastatin Rapidly and Reversibly Inhibits Insulin Secretion in Intact Single-Islet Cultures. Diabetes Ther 7(4):679-693 doi: 10.1007/s13300-016-0210-y.

4.
Ceriani F., Pozzan T., and Mammano F. (2016) Critical role of ATP-induced ATP release for Ca2+ signaling in nonsensory cell networks of the developing cochlea. Proc Natl Acad Sci U S A 113(46):E7194-E7201 doi: 10.1073/pnas.1616061113.

5.
Cali T., Frizzarin M., Luoni L., Zonta F., Pantano S., Cruz C., Bonza M.C., Bertipaglia I., Ruzzene M., De Michelis M.I., Damiano N., Marin O., Zanni G., Zanotti G., Brini M., Lopreiato R., and Carafoli E. (2016) The ataxia related G1107D mutation of the plasma membrane Ca2+ ATPase isoform 3 affects its interplay with calmodulin and the autoinhibition process. Biochim Biophys Acta 1863(1):165-173 doi: 10.1016/j.bbadis.2016.09.007.

6.
Gaj T., Sirk S.J., Shui S.-l., and Liu J. (2016) Genome-Editing Technologies: Principles and Applications. Cold Spring Harbor Perspectives in Biology:a023754 doi: 10.1101/cshperspect.a023754.

7.
Orlandini E.*, Baiesi M., Zonta F. (2016) How Local Flexibility Affects Knot Positioning in Ring Polymers. Macromolecules (online) doi: 10.1021/acs.macromol.6b00712.

8.
Wang W*, Ma P*, Dong H, Krause HJ, Zhang Y, Willbold D, Offenhaeusser A, Gu Z.(2016) A Magnetic Nanoparticles Relaxation Sensor for Protein-Protein Interaction Detection at Ultra-Low Magnetic Field. Biosens Bioelectron. 80:661-665. doi: 10.1016/j.bios.2016.02.037.

9.
Zhang H., Du M., Xie J., Liu X., Sun J., Wang W., Xin X., Possani L.D., Yea K., and Lerner R.A. (2016) Autocrine-Based Selection of Drugs that Target Ion Channels from Combinatorial Venom Peptide Libraries. Angew Chem Int Ed Engl doi: 10.1002/anie.201603052.

10.
Liu S.S., Wei X., Ji Q., Xin X., Jiang B*., and Liu J*. (2016) A facile and efficient transposon mutagenesis method for generation of multi-codon deletions in protein sequences. J Biotechnol 227:27-34 doi: 10.1016/j.jbiotec.2016.03.038.

11.
Gagliano O., Elvassore N., and Luni C. (2016) Microfluidic technology enhances the potential of human pluripotent stem cells. Biochem Biophys Res Commun 473(3):683-687 doi: 10.1016/j.bbrc.2015.12.058.

12.
Chen H., Han C., Wu J., Liu X., Zhan Y., Chen J., Chen Y., Gu R., Zhang L., Chen S., Jia J., Zhen X., Zheng L.T., and Jiang B. (2016) Accessible Method for the Development of Novel Sterol Analogues with Dipeptide-like Side Chains That Act as Neuroinflammation Inhibitors. ACS Chem Neurosci 7(3):305-315 doi: 10.1021/acschemneuro.5b00256.

13.
Wang Z., Liu N., Shi S., Liu S., and Lin H. (2016) The Role of PIWIL4, an Argonaute Family Protein, in Breast Cancer. J Biol Chem doi: 10.1074/jbc.M116.723239.

14.
Peng J.C., Valouev A., Liu N., and Lin H. (2016) Piwi maintains germline stem cells and oogenesis in Drosophila through negative regulation of Polycomb group proteins. Nat Genet 48(3):283-291 doi: 10.1038/ng.3486.

15.
Folda A., Citta A., Scalcon V., Cali T., Zonta F., Scutari G., Bindoli A., and Rigobello M.P. (2016) Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State. Sci Rep 6:23071 doi: 10.1038/srep23071.

2015
1.
Ge X.Q., Han J., Cheng E.C., Yamaguchi S., Shima N., Thomas J.L., and Lin H.F. (2015) Embryonic Stem Cells License a High Level of Dormant Origins to Protect the Genome against Replication Stress. Stem Cell Reports 5(2):185-194 doi: 10.1016/j.stemcr.2015.06.002.

2.
Gonzalez J., Qi H.Y., Liu N., and Lin H.F. (2015) Piwi Is a Key Regulator of Both Somatic and Germline Stem Cells in the Drosophila Testis. Cell Reports 12(1):150-161 doi: 10.1016/j.celrep.2015.06.004.

3.
Wu D., Kaan H.Y., Zheng X., Tang X., He Y., Vanessa Tan Q., Zhang N., and Song H. (2015) Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1. Sci Rep 5:14738 doi: 10.1038/srep14738.

4.
Yea K., Zhang H.K., Xie J., Jones T.M., Lin C.W., Francesconi W., Berton F., Fallahi M., Sauer K., and Lerner R.A. (2015) Agonist antibody that induces human malignant cells to kill one another. Proceedings of the National Academy of Sciences of the United States of America 112(45):E6158-E6165 doi: 10.1073/pnas.1519079112.

5.
Liu J., Gaj T., Yang Y., Wang N., Shui S., Kim S., Kanchiswamy C.N., Kim J.S., and Barbas C.F., 3rd (2015) Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells. Nat Protoc 10(11):1842-1859 doi: 10.1038/nprot.2015.117.

6.
庞晓楠, 弘笑, 魏璇, 陈喜文, 刘佳*, 陈德富*(2015). 乳铁蛋白的理化性质及其重组表达系统的研究进展. 遗传, 37(9): 873-884 doi: 10.16288/j.yczz.15-146

7.
Sun Y., Liu J., Jiang X., Sun T., Liu L., Zhang X., Ding S., Li J., Zhuang Y., Wang Y., and Wang R. (2015) One-Step Synthesis of Chiral Oxindole-type Analogues with Potent Anti-inflammatory and Analgesic Activities. Sci Rep 5:13699 doi: 10.1038/srep13699.

8.
Liu S.S., Wei X., Dong X., Xu L., Liu J., and Jiang B. (2015) Structural plasticity of green fluorescent protein to amino acid deletions and fluorescence rescue by folding-enhancing mutations. BMC Biochem 16(1):17 doi: 10.1186/s12858-015-0046-5.

9.
Meyer P.A., Li S., Zhang M., Yamada K., Takagi Y., Hartzog G.A., and Fu J. (2015) Structures and functions of the multiple KOW domains of transcription elongation factor Spt5. Mol Cell Biol doi: 10.1128/MCB.00520-15.

10.
Wu J., Du J., Gu R., Zhang L., Zhen X., Li Y., Chen H., Jiang B., and Zheng L. (2015) Inhibition of neuroinflammation by synthetic androstene derivatives incorporating amino acid methyl esters on activated BV-2 microglia. ChemMedChem 10(4):610-616 doi: 10.1002/cmdc.201500027.

11.
Cianci, M., Folli, C., Zonta, F., Florio, P., Berni, R. & Zanotti, G. (2015). Structural evidence for asymmetric ligand binding to transthyretin. Acta Cryst. D71 1582-1592 doi:10.1107/S1399004715010585.

12.
Yea K., Xie J., Zhang H., Zhang W., and Lerner R.A. (2015) Selection of multiple agonist antibodies from intracellular combinatorial libraries reveals that cellular receptors are functionally pleiotropic. Curr Opin Chem Biol 26C:1-7 doi: 10.1016/j.cbpa.2015.01.002.

13.
Liu J., Gaj T., Wallen M.C., and Barbas C.F., 3rd (2015) Improved cell-penetrating zinc-finger nuclease proteins for precision genome engineering. Mol Ther Nucleic Acids 4:e232 doi: 10.1038/mtna.2015.6.

14.
Gaj T. and Liu J. (2015) Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains. J Vis Exp (97) doi: 10.3791/52814.

2014
1.
Xie J., Yea K., Zhang H., Moldt B., He L., Zhu J., and Lerner R.A. (2014) Prevention of cell death by antibodies selected from intracellular combinatorial libraries. Chem Biol 21(2):274-283 doi: 10.1016/j.chembiol.2013.12.006.

2.
Lin Y., Qiu Y., Xu C., Liu Q., Peng B., Kaufmann G.F., Chen X., Lan B., Wei C., Lu D., Zhang Y., Guo Y., Lu Z., Jiang B., Edgington T.S., and Guo F. (2014) Functional role of asparaginyl endopeptidase ubiquitination by TRAF6 in tumor invasion and metastasis. J Natl Cancer Inst 106(4):dju012 doi: 10.1093/jnci/dju012.

3.
Zhao X., Qu Z., Tickner J., Xu J., Dai K., and Zhang X. (2014) The role of SATB2 in skeletogenesis and human disease. Cytokine Growth Factor Rev 25(1):35-44 doi: 10.1016/j.cytogfr.2013.12.010.

4.
Liu, J., Sun, Y., Zhang, X., Liang, X., Wu, Y., Wang, Y. and Jiang, X. (2014) Spirooxindoles, a potential novel class of anti-inflammatory agents. Inflamm. Cell Signal. 1: e372 doi: 10.14800/ics.372.

2013
1.
Jiang B., Li M.M., Xing P., and Huang Z.G. (2013) A concise formal synthesis of (-)-hamigeran B. Org Lett 15(4):871-873 doi: 10.1021/ol400030a.

2.
Yea K., Zhang H., Xie J., Jones T.M., Yang G., Song B.D., and Lerner R.A. (2013) Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections. Proc Natl Acad Sci U S A 110(37):14966-14971 doi: 10.1073/pnas.1313671110.


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