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SIAIS Hosts 2017 BioForum

Date£º30 November 2017

SIAIS hosted a successful 2017 ShanghaiTech-SIAIS BioForum at ShanghaiTech¡¯s brand-new conference center from November 13th to 16th.Read more

3rd ShanghaiTech-SIAIS BioForum a Success

Date£º13 November 2016

Shanghai Institute for Advanced Immunochemical Studies (SIAIS) in collaboration with Amgen Biopharmaceutical (Shanghai) Co., Ltd successfully held the 2016 Bio-Forum in Pudongfrom November 7th to 10th.Twenty scientists from the world¡¯s top universities and research institutions, including Nobel laureates and academicians from Chinese Academy of Science were invited to attend as distinguished speakers and more than 300 researchers and representatives of biological medicine industry attended this year¡¯s Bio-Forum.Read more

ShanghaiTech-SIAIS BioForum 2015 Convened

Date£º13 November 2015

Shanghai Institute for Advanced Immunochemical Studies (SIAIS) held the 2015 Bioforum in collaboration with Amgen Biopharmaceutical (Shanghai) Co., Ltd from November 10th-12th. Vice President and Provost Yin Jie, Deputy Director of Pudong Science and Technology Commission Gu Bing and Head of hi-tech development department of Pudong Science and Technology Commission Kong Lingyi attended the forum.Read more

ShanghaiTech-SIAIS Bioforum 2014 Held in Shanghai

Date£º23 November 2014

From November 17th to 20th, 2014 ShanghaiTech-SIAIS Bioforum was held by SIAIS in partnership with Amgen, which attracted more than 300 representatives from industry and academia around the worldRead more

The SIAIS Scientific Governance Board Held its Annual Meeting

Date£º23 November 2014

On November 17th, the SIAIS Scientific Governance Board Annual Meeting 2014 was held in ShanghaiTech University withboard members including Mianheng Jiang, President of ShanghaiTech and Shanghai Branch of Chinese Academy of Sciences(CAS).Read more


Lab of stem cell biology reveals the mechanism of Wnt/¦Â-catenin signaling pathway activation in triple negative breast cancer

Author£ºSIAIS Date£º2018-10-12

Recently, stem cell biology group has revealed a new mechanism of Wnt/¦Â-catenin signaling pathway activation in triple-negative breast cancer. The research was published in Journal of Molecular Cell Biology as ¡°Cover story¡± with the title of MiR-221/222 activate the Wnt/beta-catenin signaling to promote triple negative breast cancer.
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SIAIS Laboratory of ADC Chemistry Publish a Volume for Zinc Finger Proteins on Methods in Molecular Biology

Author£ºSIAIS Date£º2018-10-10

Research Associate Professor Jia Liu from Prof. Biao Jiang¡¯s Laboratory of ADC Chemistry in SIAIS has completed editing the 1867 volume of Methods in Molecular Biology (MiMB) with a volume title of Zinc Finger Proteins: Methods and Protocols. This volume of MiMB has been available from Springer, Amazon and other booksellers.  
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Laboratory of T Cell Engineering at SIAIS and collaborators report new technology for genome editing in CAR T cell

Author£ºSIAIS Date£º2018-10-10

Recently, Research Associate Professor Xuekai Zhu from T Cell Engineering Laboratory at SIAIS, and Professor Xingxu Huang from SLST have developed a new technology for the preparation of genome-edited chimeric antigen receptor (CAR) T cells based on non-viral vectors. The researchers used the CRISPR/Cas9 system to achieve efficient knockout of the PD-1 gene in human T cells, while stably integrating and expressing CD133-specific CAR via the transposon system. The study was published in the journal Human Gene Therapy titled with Nucleofection with Plasmid DNA for CRISPR/Cas9-Mediated Inactivation of Programmed Cell Death Protein 1 in CD133-Specific CAR T Cells.
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From the Phenotypic Screening group of Guang Yang, a hope for the treatment of a rare disease

Author£º Date£º2017-9-21

Keracthitis ¨C Ichtyosis ¨C Deafness (KID) Syndrome, is a rare genetic disease, caused by mutations of GJB2 gene, which produce severe phenotypes in skin and inner ear. Connexin 26 (Cx26) proteins, encoded by GJB2, olygomerize to form gap junction channels, which allow direct communication between two cells, or connexin hemichannels, which function as regular membrane channels. Connexin hemichannels are normally close in physiological condition, but can open in response to a variety of electrochemical stimuli. Several point mutations of Cx26 that lead to KID syndrome have been shown to produce hemichannels which do not correctly close in physiological conditions (hyperactive hemichannels).
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Laboratory of ADC Chemistry at SIAIS reports acid-labile molecular container for controlled drug release

Author£º Date£º2017-9-14

Research Associate Professor Jia Liu from SIAIS and Professor Da Ma from Fudan University has developed an acid-labile acyclic cucurbit[n]uril (CB[n]) molecular containers for controlled drug release. This study has been published on Angewandte Chemie International Edition.
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ShanghaiTech-SIAIS BioForum 2018


Advances and Perspectives in Integrative Biology of Cellular Processes  Read more

Selection of an ASIC1a blocking combinatorial antibody that protects cells from ischemic death by Dr. Min Qiang

Author£ºDr. Min Qiang
Date£º3:30 pm, Oct. 12th(Friday), 2018

Acid sensing ion channels(ASICs) have emerged as important albeit challenging therapeutic targets for pain, stroke, etc...Read more

Role of Ca2+ signaling in cell function and diseases by Katsuhiko Mikoshiba

Author£ºKatsuhiko Mikoshiba
Date£º10:00-11:00 Oct 11, 2018

Ca2+ plays an essential role in cell function. It conveys signals to the most important cell process but the detailed ...Read more

SIAIS Special Seminar by The Scripps Research Institute

Author£ºProf. Dennis Wolan

Prof. Dennis Wolan: A secreted protease from a commensal bacterium degrades human antimicrobial peptidesRead more

SIAIS Special Seminar by Dr. Wenjun Ma: Understanding of 2009 pandemic H1N1 virius

Author£ºDr. Wenjun Ma

Understanding of 2009 pandemic H1N1 virius by Dr. Wenjun Ma  Read more


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