为了推进科研院所、企业界和投资界在PROTAC药物研发领域内的交流与合作，5月16日，由免疫化学研究所主办的首届PROTAC药物发现与开发前沿论坛（Symposium on Frontier in PROTAC Drug Discovery and Development）在我校会议中心成功举办。 查看详细
近期，上海科技大学免疫化学所抗体化学实验室与分析化学平台合作，开发出新型交联剂（cross-linker），用于化学交联质谱（XL-MS）分析。该研究成果以“A novel mass spectrometry-cleavable, phosphate-based enrichable and multi-targeting protein cross-linker”为题，于2019年5月23日在英国皇家化学会旗舰期刊《chemical science》上以Edge Article的形式在线发表，并入选年度热点论文（HOT Article Collection）。查看详细
近日，上海科技大学免疫化学研究所Richard Lerner教授和杨光教授研究团队合作，研制出富含天然产物的新一代DNA编码化合物库（DNA-Encoded Library, DEL），以《Functionality-Independent DNA Encoding of Complex Natural Products》为题发表在国际顶级化学期刊Angewandte Chemie International Edition。查看详细
近日，来自免疫化学研究所特聘教授Nicola Elvassore课题组的研究人员以Microfluidic reprogramming to pluripotency of human somatic cells为题，在国际著名学术期刊《Nature Protocols》上发表了最新研究成果。 查看详细
信息来源：Invited and hosted by Prof. Biao Jiang
时间：2:00 pm, June. 21st (Friday), 2019
Dr. Luo started his independent laboratory at Memorial Sloan Kettering Cancer Center and at Weill Medical School of Cornell University in 2008. At the interface of chemistry and biology, the long-term goal of the Luo laboratory is to combine chemical and biological approaches to define, perturb and manipulate functions of diverse epigenetic modulators for disease diagnosis and therapy.查看详细
信息来源：Dr. Camilla Luni
时间：3:30 pm, May. 24th (Friday), 2019
Somatic cell reprogramming to pluripotency is the process of conversion of adult cells to a pluripotent embryonic-like state, called induced pluripotency. The discovery that pluripotency could be re-acquired by adult cells by exogenous expression of few transcription factors ...查看详细
Connexin (Cx) channels and hemichannels play numerous essential roles in virtually every organ by mediating solute exchange between adjacent cells, or between cytoplasm and extracellular environment. A number of single point pathological mutations impart a “leaky” character to the affected hemichannels, ......查看详细
DNA
encoded
chemical libraries (DELs) link the power of genetics and chemical synthesis via
combinatorial optimization. DELs comprising millions or even billions of
DNA-tagged drug
like molecules
can be ......查看详细
