Wei Wang, Ph.D.


  Wei Wang, Ph.D.

Engineer, Biomedical Big Data Platform

Email: wangwei@@shanghaitech.edu.cn


11.2014 - Present Engineer, Biomedical Big Data Platform, SIAIS, Shanghaitech University, Shanghai, China

6.2012 - 9.2014 Postdoctoral Fellow, in Bioinformatics, Institute of Biochemistry, Zhejiang University, Hangzhou, China

9.2007 - 6.2012 Ph.D. in Bioinformatics, College of Life Science, Zhejiang University, Hangzhou, China

9.2003 - 6.2007 B.S. in Bioinformatics, College of Life Science, Zhejiang University, Hangzhou, China

Representative publication:

1.   Yang, Z., M. Du, W. Wang, X. Xin, P. Ma, H. Zhang and R. A. Lerner. Affinity Maturation of an Tpor Targeting Antibody in Full-Length Igg Form for Enhanced Agonist Activity. Protein Eng Des Sel,  (2018).

2.   Fang, L., S. Y. Qi, Z. Y. Xu, W. Wang, J. He, X. Chen and J. H. Liu. De Novo Transcriptomic Profiling of Dunaliella Salina Reveals Concordant Flows of Glycerol Metabolic Pathways Upon Reciprocal Salinity Changes. Algal Research-Biomass Biofuels and Bioproducts 23,  (2017): 135-149.

3.   Piao, Z., W. Wang, Y. Wei, F. Zonta, C. Wan, J. Bai, S. Wu, X. Wang and J. Fang. Characterization of an Acetohydroxy Acid Synthase Mutant Conferring Tolerance to Imidazolinone Herbicides in Rice (Oryza Sativa). Planta,  (2017).

4.   Xu, L., A. Carrer, F. Zonta, Z. Qu, P. Ma, S. Li, F. Ceriani, D. Buratto, G. Crispino, V. Zorzi, G. Ziraldo, F. Bruno, C. Nardin, C. Peres, F. Mazzarda, A. M. Salvatore, M. Raspa, F. Scavizzi, Y. Chu, S. Xie, X. Yang, J. Liao, X. Liu, W. Wang, S. Wang, G. Yang, R. A. Lerner and F. Mammano. Design and Characterization of a Human Monoclonal Antibody That Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders. Front Mol Neurosci 10,  (2017): 298.

5.   Dou, W., J. Zhu, T. Wang, W. Wang, H. Li, X. Chen and W. Guan. Mutations of Charged Amino Acids at the Cytoplasmic End of Transmembrane Helix 2 Affect Transport Activity of the Budding Yeast Multidrug Resistance Protein Pdr5p. FEMS Yeast Res 16, no. 4 (2016).

6.   Zhu, J., W. Wang and X. Chen. Methods to Profile the Macromolecular Targets of Small Compounds. Curr Top Med Chem 16, no. 30 (2016): 3657-3667.

7.   Zhang, H., M. Du, J. Xie, X. Liu, J. Sun, W. Wang, X. Xin, L. D. Possani, K. Yea and R. A. Lerner. Autocrine-Based Selection of Drugs That Target Ion Channels from Combinatorial Venom Peptide Libraries. Angew Chem Int Ed Engl 55, no. 32 (2016): 9306-10.

8.   Chen, Z., J. Li, W. Wang, X. Guo, Y. Li, X. Mao, X. Chen and W. Guan. Mutations Adjacent to the End of Transmembrane Helices 6 and 7 Independently Affect Drug Efflux Capacity of Yeast Abc Transporter Pdr5p. Biochim Biophys Acta 1838, no. 3 (2014): 932-9.

9.   Wang, W., W. He, X. Zhou and X. Chen. Optimization of Molecular Docking Scores with Support Vector Rank Regression. Proteins 81, no. 8 (2013): 1386-98.

10. Wang, W., X. Zhou, W. He, Y. Fan, Y. Chen and X. Chen. The Interprotein Scoring Noises in Glide Docking Scores. Proteins 80, no. 1 (2012): 169-83.

11.  Xu, H., H. Xu, M. Lin, W. Wang, Z. Li, J. Huang, Y. Chen and X. Chen. Learning the Drug Target-Likeness of a Protein. Proteomics 7, no. 23 (2007): 4255-63.