Research Associate Professor, Lab of Antibody Design
Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University
Email: xuht@@shanghaitech.edu.cn
Address: Room323, Building 6, No.99 Haike Road, Pudong District, Shanghai, China
Education
2014, Ph. D in Medicinal Chemistry, Shanghai Institute of Materia Medica , Chinese Academy of Sciences, P. R. China
2006, B. S. in Pharmacy, Zhengzhou University, P. R. China
Professional
2014-present, Postdoctoral fellow, Laboratory of Antibody Chemistry, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University
Publications
1. Xu, H., Tang, H., Feng, H., & Li, Y. (2014). Design, Synthesis and Structure–Activity Relationships Studies on the D Ring of the Natural Product Triptolide. ChemMedChem, 9 (2), 290-295.
2.Xu, H., Tang, H., Feng, H., & Li, Y. (2014). Design, synthesis and anticancer activity evaluation of novel C14 heterocycle substituted epi-triptolide. European journal of medicinal chemistry, 73, 46-55.
3. Xu, H., Tang, H., Yang, Z., Feng, H., & Li, Y. (2014). Synthesis and biological evaluation of 20-hydroxytriptonide and its analogues. Tetrahedron,70 (19), 3107-3115.
4. Xu, H., Tang, H., Feng, H., & Li, Y. (2014). Divergent Total Synthesis of Triptolide, Triptonide, Tripdiolide, 16-Hydroxytriptolide, and Their Analogues. The Journal of organic chemistry, 79 (21), 10110-10122.
5. Xu, H., Tang, H., Feng, H., & Li, Y. (2014). Metal-mediate reactions based formal synthesis of triptonide and triptolide. Tetrahedron Letters, 55 (51), 7118-7120.
6. Xu, H., Chen, Y., Tang, H., Feng, H., & Li, Y. (2014). Semisynthesis of triptolide analogues: Effect of B-ring substituents on cytotoxic activities. Bioorganic & medicinal chemistry letters, 24(24), 5671-5674.