Research Associate Professor
Email: zhuxm@@shanghaitech.edu.cn
Laboratory: Lab of Stem Cells and Epigenetics 
Selected Publications:
Jing Zhang, Haiping Zhang, Lele Zhang, Dianke Li, Mengfan Qi, Liping Zhang, Huansha Yu, Di Wang, Gening Jiang, Xujun Wang*, Xianmin Zhu*, Peng Zhang*. Single-cell transcriptome identifies drug-resistance signature and immunosuppressive microenvironment in metastatic small cell lung cancer. Adv Genet. 2022, 3: 2100060.
Youjin Hu, Kevin Huang, Qiao Zeng, Yun Feng, Qiong Ke, Qin An, Lian-Ju Qin, YuGui Cui, Ying Guo, Dicheng Zhao, Yu Peng, Di Tian, Kun Xia, Yong Chen, Bin Ni, Jinmei Wang, Xianmin Zhu, Lai Wei, Yizhi Liu, Peng Xiang, Jia-Yin Liu*, Zhigang Xue*, Guoping Fan*. Single-cell analysis of nonhuman primate preimplantation development in comparison to humans and mice. Dev Dyn. 2021, 250(7):974-985.
Di He, Di Wang, Ping Lu, Nan Yang, Zhigang Xue, Xianmin Zhu*, Peng Zhang*, Guoping Fan*. Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations. Oncogene. 2021; 40(2):355-368. Ping Lu, Guang Yang, Lichun Jiang, Wen He, Wanwan Wu, Lingbin Qi, Shijun Shen, Junhua Rao, Peng Zhang, Zhigang Xue, Cizhong Jiang, Guoping Fan*, Xianmin Zhu*. Characterizing disease progression of nonalcoholic steatohepatitis in Leptin deficient rats by integrated transcriptome analysis. Experimental Biology and Medicine. 2021; 246(6):678-687. Di He, Junhui Zhang, Wanwan Wu, Ning Yi, Wen He, Ping Lu, Bin Li, Nan Yang, Di Wang, Zhigang Xue, Peng Zhang, Guoping Fan*, Xianmin Zhu*. A novel immunodeficient rat model supports human lung cancer xenografts. FASEB J. 2019, 33(1):140-150. Ganlu Hu, Kevin Huang, Youjin Hu, Guizhen Du, Zhigang Xue, Xianmin Zhu*, and Guoping Fan*. Single-cell RNA-seq reveals distinct injury responses in different types of DRG sensory neurons. Sci Rep. 2016, 6: 31851. Shuyang Xu#, Xianmin Zhu#,Hong Li#, Youtian Hu, Jinping Zhou, Di He, Yun Feng, Lina Lu, Guizhen Du, Youjin Hu, Tiancheng Liu, Zhen Wang, Guohui Ding, Jiayu Chen, Shaorong Gao, Fang Wu, Zhigang Xue, Yixue Li, and Guoping Fan*. The 14th Ile residue is essential for Leptin function in regulating energy homeostasis in rat. Sci Rep. 2016, 6: 28508. Youjin Hu, Kevin Huang, Qin An, Guizhen Du, Ganlu Hu, Jinfeng Xue, Xianmin Zhu, Cun-Yu Wang, Zhigang Xue* and Guoping Fan*. Simultaneous profiling of transcriptome and DNA methylome from a single cell. Genome Biol. 2016, 5;17(1):88. Stephen S. Gisselbrecht, Luis Barrera, Martin Porsch, Preston W. Estep, Anastasia Vedenko, Anton Aboukhalil, Alexandre Palagi, Yongsok Kim, Xianmin Zhu, Brian Busser, Caitlin E. Gamble, Antonina Iagovitina, Alan M. Michelson, Martha L. Bulyk*. Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos. Nature Methods. 2013, 10(8): 774-80. Xianmin Zhu, Shaad M. Ahmad, Anton Aboukhalil, Brian W. Busser, Yongsok Kim, Terese R. Tansey, Adrian Haimovich, Neal Jeffries, Martha L. Bulyk and Alan M. Michelson*. Differential regulation of mesodermal gene expression by Drosophila cell type- specific Forkhead transcription factors. Development. 2012, 139(8): 1457-66. Xianmin Zhu, Neetu Singh, Christopher Donnelly, Pamela Boimel and Felice Elefant*. The cloning and characterization of histone acetyltransferase human homolog Dmel\TIP60 in Drosophila melanogaster: Dmel\TIP60 is essential for multicellular development. Genetics. 2007, 175(3): 1229-40.
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