Damiano Burratto Ph.D.


  Damiano Burratto Ph.D.


Lab of Computational Biology

Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University

Email:  damiano.buratto@gmail.com  personal, dburatto@shanghaitech.edu.cn  ShanghaiTech University

Mobile: +86 18616746512 / +39 3208818126



September 2020 - now Postdoctoral position.Lab of Computational Biology (Prof. Michael Levitt), Shanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University (Shanghai, China)

December 2017 - September 2020 Postdoctoral position. Lab of Phenotypic Screening (Prof. Yang Guang), Shanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University (Shanghai, China)

September 2017 – November 2017 assignment collaboration N. 03/2017. Department of biomedical sciences, University of Padua (Italy)

April 2017 – July 2017 assignment collaboration N. 02/2017. Istituto di Biologia Cellulare e Neurobiologia (IBCN) del CNR (Italy)

January 2014 – April 2017 Ph.D. in Physics, Curriculum: Biophysics. Department of Physics and Astronomy, University of Padua (Italy)

October 2008 – October 2013 B.Sc. / M.Sc. in Physics. Department of Physics and Astronomy, University of Padua (Italy)


Buratto D.; Donati V.; Zonta F.; Mammano F. Harnessing the Therapeutic Potential of Antibodies Targeting Connexin Hemichannels.BBA - Molecular Basis of Disease, accepted manuscript.


Martewicz, S.; Luni, C.; Zhu, X.; Cui, M.; Hu, M.; Qu, S.; Buratto, D.; Yang, G.; Grespan, E.; Elvassore, N. Nuclear Morphological Remodeling in Human Granulocytes Is Linked to Prenylation Independently from Cytoskeleton.Cells. Nov2020, 9, 2509.


Kuang Y.*, Zorzi V.*, Buratto D., Ziraldo G., Mazzarda F., Peres C., Nardin C., Salvatore A.M., Chiani F., Schiavizzi F., Qiang M., Chu Y., Shi X., Li Y., Liu L., Zonta F., Yang G., Lerner R.A., Mammano F., A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice. EBioMedicine. 2020 Jun 12;102825. doi: 10.1016/j.ebiom.2020.102825.


Ma P., Xu H., Li J., Lu F., Ma F., Wang S., Xiong H., Wang W., Buratto D., Zonta F., Wang N., Liu K., Hua T., Yang G., Lerner  R.A., Functionality-Independent DNA Encoding of Complex Natural ProductsAngew Chem Int Ed Engl. 2019 Jul 1;58(27):9254-9261.


Buratto D.*, Ziraldo G.*, Kuang Y., Liang X., Carrer A., Nardin C., Chiani F., Salvatore A.M., Lerner R.A., Yang G., Zonta F., Mammano F., A Human-Derived Monoclonal Antibody Targeting Extracellular Connexin Domain Selectively Modulates Hemichannel Function. Front Physiol. 2019 Jun11, 10: 392. (*co-first author)


Zonta F., Buratto D., Crispino G., Carrer A., Bruno F., Yang G., Mammano F., Pantano S., Cues to opening mechanisms from in silico electric field excitation of Cx26 hemichannel and in vitro mutagenesis studies in HeLa transfectans. Frontiers in molecular neuroscience. 2018; 11:170.


Qiang M.*Dong X.*Zha Z.Zuo X.K.,Song X.L.Zhao L., Yuan C., Huang C., Tao P., Hu Q., Li W.G., Hu W., Li J., Nie Y.,Buratto D., … , Yang G., and Lerner R.A.Selection of an ASIC1a-blocking combinatorial antibody that protects cells from ischemic deathProceedings of the National Academy of Sciences. 2018 Aug 7; 115(32):E7469-77.


Xu L.*, Carrer A.*, Zonta F.*, Ma P., Qu Z., Li S., Buratto D., Ceriani F., Crispino G., Zorzi V., Ziraldo G., Bruno F., Nardin C., Peres C., Mazzarda F., Salvatore A.M., Raspa M.,  Scavizzi F., Chu Y., Xie S., Liao J., Liu X., Wang W., Wang S., Guang Y., Lerner R.A., Mammano F., Design and characterization of a human monoclonal antibody that modulates mutant connexin 26 hemichannels implicated in deafness and skin disorders. Frontiers in Molecular Neuroscience Vol 10, Article 298, 2017.


Zonta F., Girotto G., Buratto D., Crispino G., Morgan A., Abdulhadi K., Alkowari M., Badii R., Gasparini P., Mammano F., The p.Cys169Tyr variant of connexin 26 is not a polymorphismHuman Molecular Genetics 24(9): 2641-2648, 2015.


Zonta F., Buratto D., Cassini C., Bortolozzi M., Mammano F., Molecular dynamics simulations highlight structural and functional alterations in deafness-related M34T mutation of connexin26, (invited research article; cover articleFrontiers in Physiology,  Vol 5, Article 85, pages 1-9, 2014.