Research Assistant Professor
E-mail: dongyx@@shanghaitech.edu.cn Phone: 021-20684480  Research Interests: Elucidating the mechanisms of how matrix mechanics program stem cells in a 3D microenvironment and affect tumor metastasis; Synthetic and natural multi-functional biomaterials for stem cell therapy and tissue regeneration; 3D bio-printing and organoid on a chip.
Biography: 11/2017-Present: Research Assistant Professor at SIAIS, ShanghaiTech University,China
01/2015-12/2016: Postdoctoral Research Fellow (Visiting Scholar) at Department of Surgery, School of Medicine, Stanford University, Stanford, CA, United States
02/2014-09/2017: Postdoctoral Research Fellow at Charles Institute of Dermatology, University College Dublin, Ireland
09/2013-02/2014: Postdoctoral Researcher at Network of Excellence for Functional Biomaterials, National University of Ireland Galway, Ireland 2013 Ph.D. in Mechanical and Biomedical Engineering, National University of Ireland Galway, Ireland
2009 M.Sc. in Biomedical Science, National University of Ireland Galway, Ireland
2001 B.Sc. in Microbiology, Nanjing Agriculture University, China
Representative Publications:
(*Corresponding author; # Contributed equally) 15. Qian S. #; Dong Y. #*; Qu J; Wang X; Zhang W.; Chen J.; Xu F.; Cui M.; Giomo M.; Liao C.; Hu M.; Xu J.; Hu G.; Zheng J.; Zhu X.; Urciuolo A.*; Fan G.*; Elvassore N.*. ‘Tunable hydrogel confinement via on-chip 3D printing for studying cancer cell migration.’ ACS Materials Letters, 2023, DOI: 10.1021/acsmaterialslett.3c00853. 14. Urciuolo A. #*; Giobbe G. #; Dong Y. #; Michielin F.; Brandolino L.; Magnussen M.; Gagliano O.; Selmin G.; Scattolini V.; Raffa P.; Caccin P.; Shibuya S.; Scaglioni D.; Wang X.; Qu J.; Nikolic M.; Montagner M.; Galea G.; Clevers H.; Giomo M.; De Coppi P.; Elvassore N.* ‘Hydrogel-in-hydrogel live bioprinting for guidance and control of organoids and organotypic cultures’. Nature Communications, 2023,14:3128. 13. Dong, Y.*; Cui, M.; Qu, J.; Wang, X.; Kwon, S.H.; Barrera, J.; Elvassore, N.; Gurtner, C.G. ‘Conformable hyaluronic acid hydrogel delivers adipose-derived stem cells and promotes regeneration of burn injury’ Acta Biomaterialia, 2020, 108:55-56. 12. Dong, Y.*; Rodrigues, M.; Kwon, S.H.; Li, X.; A, S.; Brett, E.A.; Elvassore, N.; Wang, W.; Gurtner, C.G. ‘Acceleration of diabetic wound regeneration using an in-situ-formed stem cell-based skin substitute’. Advanced Healthcare Materials, 2018, 201800432. 11. Dong, Y.*; A, S.; Rodrigues, M.; Li, X.; Kwon, S.H.; Kosaric, N.; Khong, S.; Gao, Y.; Wang, W.; Gurtner, C.G. ‘Injectable and tunable gelatin hydrogels enhance stem cell retention and improve cutaneous wound healing’. Advanced Functional Materials, 2017, 1606619. 10. Cao, H.; Dong, Y.; Bre, L.; Tapeinos, C.; Wang, W.; Pandit, A. ‘An acetal-based polymeric crosslinker with controlled pH-sensitivity’. RSC Advances, 2016, 6: 9604-9611. 9. Dong, Y.*; Qin, Y.; Dubaa M.; Killion, J; Gao, Y.; Zhao, T.; Zhou, D.; Duscher, D.; Geever, L.; Gurtner, C.G.; Wang, W. ‘A rapid crosslinking injectable hydrogel for stem cell delivery, from multifunctional hyperbranched polymers via RAFT homopolymerization of PEGDA'. Polymer Chemistry, 2015, 6: 6182-6192. 8. Cao, H.; Dong, Y.; Aied, A.; Zhao, T.; Chen, X.; Wang, W.; Pandit, A. ‘Acetal-linked branched poly(dimethyl-aminoethyl methacrylat) as an acid cleavable gene vector with reduced cytotoxicity.’ Chemical Communications, 2014, 50: 15565-15568. 7. Dong, Y.; Hassan, W.; Kennedy, R.; Greiser, U.; Pandit, A.; Garcia, Y.; Wang, W. ‘Performance of an in-situ formed bioactive hydrogel dressing from a PEG-based hyperbranched multi-functional copolymer.’ Acta Biomaterialia, 2014, 10: 2076-2085. 6. Dong, Y.; Aied, A.; Li, J.; Wang, Q.; Hu, X.; Wang, W. ‘An in vitro approach for production of non-scar minicircle DNA vectors.’ Journal of Biotechnology, 2013, 166: 84-87. 5. Hassan, W#, Dong, Y.# and Wang, W. ‘Encapsulation and 3D culture of human adipose-derived stem cells in an in-situ crosslinked hybrid hydrogel composed of PEG-based hyperbranched copolymer and hyaluronic acid’. Stem Cell Research & Therapy. 2013, 4:32. 4. Dong, Y.; Hassan, W.; Zheng, Y.; Saeed, A.O.; Cao, H.; Tai, H.; Pandit, A.; Wang, W. 'Thermoresponsive hyperbranched copolymer with multi acrylate functionality for in situ cross-linkable hyaluronic acid composite semi-IPN hydrogel', Journal of Materials Science: Materials in Medicine, 2012, 23 (1), 25-35. 3. Dong, Y.; Saeed, A.O.; Hassan, W.; Keigher, C.; Zheng, Y.; Tai, H.; Pandit, A.; Wang, W. 'One-step preparation of thiol-ene clickable PEG based thermoresponsive hyperbranched copolymer for in situ crosslinking hybrid hydrogel', Macromolecular Rapid Communications, 2012, 33, 120-136. 2. Cao, H.; Dong, Y.; O’Rorke, S.; Wang, W.; Pandit, A. ‘PEG based hyperbranched polymeric hollow nanospheres’ Nanotechnology, 2011, 22, 065604 1. Dong, Y.; Gunning, P.; Cao, H.; Mathew, A.; Newland, B. E.; Saeed, A. O.; Magnusson, J. P.; Alexander, C.; Tai, H.; Pandit, A.; Wang, W. ‘Dual stimuli responsive PEG based hyperbranched polymers’ Polymer Chemistry, 2010, 1, 827-830. |
