2022

1、mRNA based vaccines provide broad protection against different SARS-CoV-2 variants of concern.Wang, Haomeng(1,3,4);Chen, Zhao(2);Wang, Zhenghua(1,3,4);Li, Jin(1,3,4);Yan, Zhihong(1,3,4);Yuan, Jinbo(1,3,4);Zhu, Airu(2);Chen, Lan(2);Liu, Ye(1,3,4);Hu, Chenlong(1,3,4);Zhu, Ali(1);Li, Guowei(1,3,4);Li, Yuehu(1,3,4);Deng, Jie(3);Ma, Liqiao(3);Sui, Xiuwen(3);Miao, Wei(3);Li, Junqiang(3);Zheng, Xiuyu(3);Piao, Jinhua(3);Yao, Yanfeng(8);Rao, Juhong(9);Shan, Chao(9,10);Yuan, Zhiming(8);Zhao, Jincun(2,5,6,7);Zhu, Tao(1,3,4).2022-12-31.EMERGING MICROBES & INFECTIONS

2、Structures of adenosine receptor A(2B)R bound to endogenous and synthetic agonists.Cai, Hongmin(1);Xu, Youwei(1);Guo, Shimeng(2);He, Xinheng(1,3);Sun, Jun(2,3);Li, Xin(2,3);Li, Changyao(1,3);Yin, Wanchao(1,3,4);Cheng, Xi(1,3,5);Jiang, Hualiang(1,3,5,6,7);Xu, H. Eric(1,3,6,8);Xie, Xin(2,3,5,6,8);Jiang, Yi(6,7).2022-12-28.CELL DISCOVERY

3、Insights into divalent cation regulation and G(13)-coupling of orphan receptor GPR35.Duan, Jia(1,2);Liu, Qiufeng(1);Yuan, Qingning(1);Ji, Yujie(1,2);Zhu, Shengnan(3);Tan, Yangxia(1);He, Xinheng(1,2);Xu, Youwei(1);Shi, Jingjing(1);Cheng, Xi(1,2,4);Jiang, Hualiang(1,2,4,5,6);Eric Xu, H.(1,2,5,6);Jiang, Yi(1,2,5,7).2022-12-21.CELL DISCOVERY

4、Discovery and characterization of novel potent BCR-ABL degraders by conjugating allosteric inhibitor.Liu, Haixia(1,3,5);Mi, Qianglong(1,2);Ding, Xinyu(1,2,5);Lin, Chencen(1,3,5);Liu, Linyi(4);Ren, Chaowei(1,2,5);Shen, Shu Ting(1,2,5);Shao, Yu Bao(6);Chen, Jinju(1);Zhou, Yongqi(1);Ji, Liting(1);Zhang, Heqiao(1);Bai, Fang(1);Yang, Xiaobao(1,8);Yin, Qianqian(1);Jiang, Biao(1,7).2022-12-15.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

5、Professor Ernesto Carafoli: a Personal Appreciation.Mikoshiba, Katsuhiko(1,2,3).2022-12-10.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

6、An armed oncolytic virus enhances the efficacy of tumor-infiltrating lymphocyte therapy by converting tumors to artificial antigen-presenting cells in situ.Ye, Kai(1,3,5);Li, Fan(1,3,5);Wang, Ruikun(1,3,5);Cen, Tianyi(1,3,5);Liu, Shiyu(1,3,5);Zhao, Zhuoqian(1,3,5);Li, Ruonan(1,3,5);Xu, Lili(1,3,5);Zhang, Guanmeng(2);Xu, Zhaoyuan(2);Deng, Li(3,4);Li, Lili(3,4);Wang, Wei(6);Stepanov, Alexey(7);Wan, Yajuan(1);Guo, Yu(1,3,5);Li, Yuanke(1,3,5);Wang, Yuan(1,3,5);Tian, Yujie(3,5);Gabibov, Alexander G.(7);Yan, Yingbin(2);Zhang, Hongkai(1,3,5).2022-12-07.MOLECULAR THERAPY

7、GIT1 protects against breast cancer growth through negative regulation of Notch.Zhang, Songbai(1);Miyakawa, Ayako(1,2);Wickström, Malin(3);Dyberg, Cecilia(3);Louhivuori, Lauri(1);Varas-Godoy, Manuel(1,4);Kemppainen, Kati(5,6);Kanatani, Shigeaki(1);Kaczynska, Dagmara(1);Ellström, Ivar Dehnisch(1);Elfman, Lotta(3);Kronqvist, Pauliina(7);Repo, Heli(7);Mikoshiba, Katsuhiko(8,9,10);Sahlgren, Cecilia(5,6,11);Johnsen, John Inge(3);Uhlén, Per(1).2022-12-01.NATURE COMMUNICATIONS

8、Virus spread on a scale-free network reproduces the Gompertz growth observed in isolated COVID-19 outbreaks.Zonta, Francesco(2);Levitt, Michael(1).2022-12-01.ADVANCES IN BIOLOGICAL REGULATION

9、PanGu Drug Model: learn a molecule like a human.Lin, Xinyuan(1);Xu, Chi(1);Xiong, Zhaoping(1);Zhang, Xinfeng(1);Ni, Ningxi(1);Ni, Bolin(1);Chang, Jianlong(1);Pan, Ruiqing(1);Wang, Zidong(1);Yu, Fan(1);Tian, Qi(1);Jiang, Hualiang(2,3,4);Zheng, Mingyue(4);Qiao, Nan(1).2022-12-01.SCIENCE CHINA-LIFE SCIENCES

10、Synthesis of maleimide-braced peptide macrocycles and their potential anti-SARS-CoV-2 mechanisms.Li, Jian(1,2);Sun, Jina(2,3);Zhang, Xianglei(4,5);Zhang, Ruxue(6);Wang, Qian(1,2);Wang, Lin(4,5);Zhang, Leike(6);Xie, Xiong(2,3);Li, Chunpu(2,3);Zhou, Yu(2,3);Wang, Jiang(2,3);Xiao, Gengfu(6);Bai, Fang(4,5);Liu, Hong(1,2,3).2022-12-01.CHEMICAL COMMUNICATIONS

11、Chromosome-length genome assemblies of six legume species provide insights into genome organization, evolution, and agronomic traits for crop improvement.Garg, Vanika(1);Dudchenko, Olga(2,3);Wang, Jinpeng(4);Khan, Aamir W.(1);Gupta, Saurabh(5);Kaur, Parwinder(6);Han, Kai(7);Saxena, Rachit K.(1);Kale, Sandip M.(8);Pham, Melanie(2);Yu, Jigao(4);Chitikineni, Annapurna(1);Zhang, Zhikang(4);Fan, Guangyi(7,9);Lui, Christopher(2);Valluri, Vinodkumar(1);Meng, Fanbo(4);Bhandari, Aditi(1);Liu, Xiaochuan(7);Yang, Tao(10);Chen, Hua(11);Valliyodan, Babu(12);Roorkiwal, Manish(1);Shi, Chengcheng(7);Bin Yang, Hong(13);Durand, Neva C.(2,3);Pandey, Manish K.(1,14);Li, Guowei(15);Barmukh, Rutwik(1);Wang, Xingjun(15);Chen, Xiaoping(13);Lam, Hon-Ming(16,17);Jiang, Huifang(18);Zong, Xuxiao(10);Liang, Xuanqiang(13);Liu, Xin(7,9,19);Liao, Boshou(18);Guo, Baozhu(20);Jackson, Scott(21);Nguyen, Henry T.(22,23);Zhuang, Weijian(11);Shubo, Wan(15);Wang, Xiyin(4);Aiden, Erez Lieberman(2,3,6,24,25);Bennetzen, Jeffrey L.(26);Varshney, Rajeev K.(1,11,14,27,28).2022-12-01.JOURNAL OF ADVANCED RESEARCH

12、Biodegradation of highly crystallized poly(ethylene terephthalate) through cell surface codisplay of bacterial PETase and hydrophobin.Chen, Zhuozhi(1);Duan, Rongdi(1);Xiao, Yunjie(1);Wei, Yi(1);Zhang, Hanxiao(1);Sun, Xinzhao(1);Wang, Shen(1);Cheng, Yingying(1);Wang, Xue(1);Tong, Shanwei(1);Yao, Yunxiao(1);Zhu, Cheng(1);Yang, Haitao(1,2,3);Wang, Yanyan(1);Wang, Zefang(1,2).2022-11-21.NATURE COMMUNICATIONS

13、DeepPROTACs is a deep learning-based targeted degradation predictor for PROTACs.Li, Fenglei(1,2);Hu, Qiaoyu(1);Zhang, Xianglei(1);Sun, Renhong(3);Liu, Zhuanghua(2);Wu, Sanan(1);Tian, Siyuan(1,4);Ma, Xinyue(1,2);Dai, Zhizhuo(4);Yang, Xiaobao(3);Gao, Shenghua(2);Bai, Fang(1,2,4,5).2022-11-21.NATURE COMMUNICATIONS

14、Utilization of macrocyclic peptides to target protein-protein interactions in cancer.Yang, Jiawen(1,2,3);Zhu, Qiaoliang(1);Wu, Yifan(2,4,5);Qu, Xiaojuan(2,4,5);Liu, Haixia(2,5,6);Jiang, Biao(2,7);Ge, Di(1);Song, Xiaoling(2).2022-11-17.FRONT. ONCOL.

15、A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors.Yan, Liming(1);Huang, Yucen(1,3);Ge, Ji(1,2);Liu, Zhenyu(1,4,5);Lu, Pengchi(6);Huang, Bo(7);Gao, Shan(1);Wang, Junbo(1);Tan, Liping(1);Ye, Sihan(1);Yu, Fengxi(3);Lan, Weiqi(4,5);Xu, Shiya(1);Zhou, Feng(7);Shi, Lei(7);Guddat, Luke W.(8);Gao, Yan(4,5);Rao, Zihe(1,2,4,5,9,10,11);Lou, Zhiyong(1).2022-11-10.CELL

16、Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.Zhuang, Youwen(1);Wang, Yue(1,2);He, Bingqing(2,3,4);He, Xinheng(1,2);Zhou, X. Edward(5);Guo, Shimeng(2,3,6);Rao, Qidi(4);Yang, Jiaqi(1);Liu, Jinyu(6);Zhou, Qingtong(7);Wang, Xiaoxi(1);Liu, Mingliang(1);Liu, Weiyi(1,2);Jiang, Xiangrui(1,2);Yang, Dehua(1,2,3);Jiang, Hualiang(1,2,4);Shen, Jingshan(1,2);Melcher, Karsten(5);Chen, Hong(8,9);Jiang, Yi(1,2);Cheng, Xi(1,2);Wang, Ming-Wei(1,2,3,4,7);Xie, Xin(1,2,3,4,6,10);Xu, H. Eric(1,2).2022-11-10.CELL

17、Comparative phylogenomic analyses and co-expression gene network reveal insights in flowering time and aborted meiosis in woody bamboo, Bambusa oldhamii 'Xia Zao' ZSX.Zhao, Wanqi(1);Guo, Chunce(2);Yao, Wenjing(1);Zhang, Li(1);Ding, Yulong(1);Yang, Zhenzhen(3);Lin, Shuyan(1).2022-11-09.FRONTIERS IN PLANT SCIENCE

18、Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir.Iketani, Sho(1,2);Mohri, Hiroshi(1,2);Culbertson, Bruce(3,4);Hong, Seo Jung(5);Duan, Yinkai(6,7);Luck, Maria, I(1,2);Annavajhala, Medini K.(2);Guo, Yicheng(1,2);Sheng, Zizhang(1,2);Uhlemann, Anne-Catrin(2);Goff, Stephen P.(1,8,9);Sabo, Yosef(1,2);Yang, Haitao(6,7);Chavez, Alejandro(5);Ho, David D.(1,2,8).2022-11-09.NATURE

19、Antigenic mapping reveals sites of vulnerability on alpha-HCoV spike protein.Xiang, Jiangchao(1,2,3);Su, Jie(1);Lan, Qiaoshuai(4);Zhao, Wenwen(1);Zhou, Yu(1);Xu, Youwei(1);Niu, Jun(1);Xia, Shuai(4);Qi, Qilian(1);Sidhu, Sachdev(5);Lu, Lu(4);Miersch, Shane(5);Yang, Bei(1,6).2022-11-04.COMMUNICATIONS BIOLOGY

20、Transcriptional and functional consequences of alterations to MEF2C and its topological organization in neuronal models.Mohajeri, Kiana(1,2,3,4,5,6);Yadav, Rachita(1,2,3,4,5);D'haene, Eva(7);Boone, Philip M.(1,2,3,8);Erdin, Serkan(1,2);Gao, Dadi(1,2,3,4,5);Moyses-Oliveira, Mariana(1,2,3,4,5);Bhavsar, Riya(1,2,3);Currall, Benjamin B.(1,2,3);O'Keefe, Kathryn(1,2,3);Burt, Nicholas D.(1,2,3);Lowther, Chelsea(1,2,3,4,5);Lucente, Diane(1,4,5);Salani, Monica(1,2,3);Larson, Mathew(1);Redin, Claire(1,16);Dudchenko, Olga(9,10,11);Aiden, Erez Lieberman(9,10,11,12,13,14);Menten, Bjorn(7);Tai, Derek J. C.(1,2,3,4,5);Gusella, James F.(1,3,6,15);Vergult, Sarah(7);Talkowski, Michael E.(1,2,3,4,5,6).2022-11-03.AMERICAN JOURNAL OF HUMAN GENETICS

21、PPI-Miner: A Structure and Sequence Motif Co-Driven Protein-Protein Interaction Mining and Modeling Computational Method.Wang, Lin(1);Li, Feng-lei(1);Ma, Xin-yue(1);Cang, Yong(2);Bai, Fang(1,3).2022-11-01.JOURNAL OF CHEMICAL INFORMATION AND MODELING

22、A chromosome-length genome assembly and annotation of blackberry (Rubus argutus, cv. Hillquist).Bruna, Tomas(1);Aryal, Rishi(2);Dudchenko, Olga(3,4,5);Sargent, Daniel James(6,7);Mead, Daniel(8,9);Buti, Matteo(10);Cavallini, Andrea(11);Hytonen, Timo(12);Andres, Javier(12);Pham, Melanie(13);Weisz, David(13);Mascagni, Flavia(11);Usai, Gabriele(11);Natali, Lucia(11);Bassil, Nahla(14);Fernandez, Gina E.(2);Lomsadze, Alexandre(15);Armour, Mitchell(16);Olukolu, Bode(17);Poorten, Thomas(18);Britton, Caitlin(18);Davik, Jahn(19);Ashrafi, Hamid(20);Aiden, Erez Lieberman(4,5,13,21,22,23);Borodovsky, Mark(24);Worthington, Margaret(16).2022-11-01.G3-GENES GENOMES GENETICS

23、Microvesicle-inspired oxygen-delivering nanosystem potentiates radiotherapy-mediated modulation of tumor stroma and antitumor immunity.Gong, Xiang(1);Li, Jie(1);Xu, Xiaoxuan(1);Wu, Yao(1,2);Lei, Ying(3);Liu, Huanzhen(3);Qian, Xindi(1);Li, Yaping(1);Zhang, Zhiwen(1,2).2022-11.BIOMATERIALS

24、ROS-Responsive Nanocomplex of aPD-L1 and Cabazitaxel Improves Intratumor Delivery and Potentiates Radiation-Mediated Antitumor Immunity.Wang, Jiaoying(1,2);Li, Jie(2);Wu, Yao(4);Xu, Xiaoxuan(2);Qian, Xindi(2);Lei, Ying(5);Liu, Huanzhen(5);Zhang, Zhiwen(4);Li, Yaping(1,2,3).2022-10-26.NANO LETTERS

25、Structure-based design of anti-mycobacterial drug leads that target the mycolic acid transporter MmpL3.Hu, Tianyu(1,2,7,8);Yang, Xiaolin(1,2);Liu, Fengjiang(3);Sun, Shan(1,2);Xiong, Zhiqi(4);Liang, Jingxi(5);Yang, Xiaobao(1,2);Wang, Haofeng(1,2);Yang, Xiuna(1,2,9);Guddat, Luke W.(6);Yang, Haitao(1,2,9);Rao, Zihe(1,2,3,4,5,9);Zhang, Bing(1,2,9).2022-10-06.STRUCTURE

26、Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease.Song, Jia(1,2);Yang, Rui-rui(2,3,4,5);Chang, Jie(2);Liu, Ya-dan(6);Lu, Cheng-hao(6);Chen, Li-fan(2,3);Guo, Hao(2,3);Zhang, Ying-hui(2,3);Fan, Zi-sheng(2,6);Zhou, Jing-yi(2,6);Zhou, Gui-zhen(2,6);Zhang, Ke-ke(2,6);Luo, Xiao-min(2,3,6);Chen, Kai-xian(2,3,6);Jiang, Hua-liang(1,2,3,4,5,6);Zhang, Su-lin(2,6);Zheng, Ming-yue(2,3,6).2022-10.ACTA PHARMACOLOGICA SINICA

27、Global Transcriptional and Epigenetic Reconfiguration during Chemical Reprogramming of Human Retinal Pigment Epithelial Cells into Photoreceptor-like Cells.Deng, Xiaoqian(1,2);Lee, Ryan(2);Lim, Sin Yee(2);Zhong, Zheng(3);Wang, Jing(2);Liu, Yizhi(1);Fan, Guoping(2,4).2022-10.CELLS

28、Comparison of pandemic excess mortality in 2020-2021 across different empirical calculations.Levitt, Michael(1);Zonta, Francesco(2);Ioannidis, John P. A.(3,4,5,6,7,8).2022-10.ENVIRONMENTAL RESEARCH

29、Toward an accurate mechanistic understanding of Wolbachia-induced cytoplasmic incompatibility (Invited Review).Wang, Wei(1);Cui, Wen(1);Yang, Haitao(2,3,4).2022-10.ENVIRONMENTAL MICROBIOLOGY

30、Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma.Han, Qi-lei(1);Zhang, Xiang-lei(2);Ren, Peng-xuan(2,3);Mei, Liang-he(4);Lin, Wei-hong(1);Wang, Lin(2,3);Cao, Yu(2,3);Li, Kai(1);Bai, Fang(2,3,5,6).2022-10.ACTA PHARMACOLOGICA SINICA

31、Structural basis for strychnine activation of human bitter taste receptor TAS2R46.Xu, Weixiu(1,2);Wu, Lijie(1);Liu, Shenhui(1,2);Liu, Xiao(1,2);Cao, Xiaoling(1,2);Zhou, Cui(1,2);Zhang, Jinyi(1,2);Fu, You(1,2);Guo, Yu(1);Wu, Yiran(1);Tan, Qiwen(1);Wang, Ling(1);Liu, Junlin(1);Jiang, Longquan(1,2);Fan, Zhongbo(1,2);Pei, Yuan(1);Yu, Jingyi(3);Cheng, Jianjun(1,2);Zhao, Suwen(1,2);Hao, Xiaojiang(4);Liu, Zhi-Jie(1,2);Hua, Tian(1,2).2022-09-16.SCIENCE

32、PiLSL: pairwise interaction learning-based graph neural network for synthetic lethality prediction in human cancers.Liu, Xin(1);Yu, Jiale(1);Tao, Siyu(1);Yang, Beiyuan(1);Wang, Shike(1);Wang, Lin(2,3);Bai, Fang(1,2,3);Zheng, Jie(1,4).2022-09-16.BIOINFORMATICS

33、Metal-Free and Open-Air Arylation Reactions of Diaryliodonium Salts for DNA-Encoded Library Synthesis.Xu, Hongtao(1);Tan, Tingting(1);Zhang, Yiyuan(1);Wang, Yan(1);Pan, Kangyin(1);Yao, Ying(1);Zhang, Shuning(1);Gu, Yuang(1);Chen, Wanting(1);Li, Jie(1);Dong, Hewei(2);Meng, Yu(2);Ma, Peixiang(1,3);Hou, Wei(2);Yang, Guang(1).2022-09-15.ADVANCED SCIENCE

34、Construction of a Deep Neural Network Energy Function for Protein Physics.Yang, Huan(1);Xiong, Zhaoping(1);Zonta, Francesco(1).2022-09-13.JOURNAL OF CHEMICAL THEORY AND COMPUTATION

35、ADSCs stimulated by VEGF-C alleviate intestinal inflammation via dual mechanisms of enhancing lymphatic drainage by a VEGF-C/VEGFR-3-dependent mechanism and inhibiting the NF-κB pathway by the secretome.Zhang, Lei(1);Ye, Chen(2);Li, Peng(3);Li, Chuanding(1);Shu, Weigang(1);Zhao, Yujie(1);Wang, Xiaolei(1).2022-09-05.STEM CELL RESEARCH AND THERAPY

36、Clickable Selenylation - a Paradigm for Seleno-Medicinal Chemistry.Hou, Wei(1,2);Dong, Hewei(1,2);Yao, Ying(3);Pan, Kangyin(3);Yang, Guang(3);Ma, Peixiang(3,4);Xu, Hongtao(3).2022-09-05.CHEMMEDCHEM

37、Pathogenesis, therapeutic strategies and biomarker development based on omics analysis related to microglia in Alzheimer's disease.Gao, Chao(1);Shen, Xin(1);Tan, Yuyan(1);Chen, Shengdi(1,2).2022-09-04.JOURNAL OF NEUROINFLAMMATION

38、A History of the Origin and Development of Japanese Society for Neurochemistry: International Cooperation to Overcome Dementia and Mental Illness.Mikoshiba, Katsuhiko(1,2,3,4).2022-09.NEUROCHEMICAL RESEARCH

39、Structural insights into ligand binding and activation of the human thyrotropin-releasing hormone receptor.Xu, Youwei(1,5);Cai, Hongmin(1,5);You, Chongzhao(1,2);He, Xinheng(1,2);Yuan, Qingning(1);Jiang, Hualiang(1,2,3,4);Cheng, Xi(1,4);Jiang, Yi(1);Xu, H. Eric(1,2,3).2022-09.CELL RESEARCH

40、In Silico Maturation of a Nanomolar Antibody against the Human CXCR2.Buratto, Damiano(1,2);Wan, Yue(1,3);Shi, Xiaojie(1);Yang, Guang(1);Zonta, Francesco(1).2022-09.BIOMOLECULES

41、Computationally Elucidating the Binding Kinetics for Different AChE Inhibitors to Access the Rationale for Improving the Drug Efficacy.Bai, Fang(3,4);Jiang, Hualiang(1,2).2022-09.JOURNAL OF PHYSICAL CHEMISTRY B

42、Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer.Wang, Ya-fang(1,2);Yu, Lei(1,3);Hu, Zong-long(1);Fang, Yan-fen(1);Shen, Yan-yan(1);Song, Min-fang(4);Chen, Yi(1,3).2022-08-29.CELL DEATH & DISEASE

43、Selenylation Chemistry Suitable for On-Plate Parallel and On-DNA Library Synthesis Enabling High-Throughput Medicinal Chemistry.Xu, Hongtao(1);Wang, Yan(1);Dong, Hewei(2,3);Zhang, Yiyuan(1);Gu, Yuang(1);Zhang, Shuning(1);Meng, Yu(2,3);Li, Jie(1);Shi, Xiao Jie(1);Ji, Qun(1);Liu, Lili(1);Ma, Peixiang(1,4,5);Ma, Fei(1);Yang, Guang(1);Hou, Wei(2,3).2022-08-26.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

44、Reactive oxygen species-responsive Pre-PROTAC for tumor-specific protein degradation.Liu, Haixia(1,2);Ren, Chaowei(1,3);Sun, Renhong(1);Wang, Huihui(1,3);Zhan, Yuexiong(1);Yang, Xiaobao(1,4);Jiang, Biao(1,2,3,5);Chen, Hongli(1).2022-08-12.CHEMICAL COMMUNICATIONS

45、Specific gut microbiota alterations in essential tremor and its difference from Parkinson’s disease.Zhang, Pingchen(1);Huang, Pei(1);Du, Juanjuan(1);He, Yixi(1);Liu, Jin(1);He, Guiying(1);Cui, Shishuang(1);Zhang, Weishan(1);Li, Gen(1);Chen, Shengdi(1,2).2022-08-05.NPJ PARKINSON'S DISEASE

46、Discovery and characterization of novel potent BCR-ABL degraders by  conjugating allosteric inhibitor.Liu,Haixia(1,3,5);Mi,Qianglong(1,2);Ding,xinyu(1,2,5);Lin,Chencen(1,3,5);Liu,Linyi(4);Ren,Chaowei(1,2,5);Shen,Shuting(1,2,5);Shao,Yubao(6);Chen,jinju(1);Zhou,yongqi(1);Ji,Liting(1);Zhang,Heqiao(1);Bai,Fang(1);Yang,Xiaobao(1,8);Yin,Qianqian(1);Jiang,Biao(1,7).2022-08-04.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

47、A Chromosome-Length Reference Genome for the Endangered Pacific Pocket Mouse Reveals Recent Inbreeding in a Historically Large Population.Wilder, Aryn P.(1);Dudchenko, Olga(2,3,4);Curry, Caitlin(1);Korody, Marisa(1);Turbek, Sheela P.(1,5);Daly, Mark(6);Misuraca, Ann(1);Wang, Gaojianyong(7);Khan, Ruqayya(2);Weisz, David(2);Fronczek, Julie(1);Aiden, Erez Lieberman(2,3,4,8,9,10);Houck, Marlys L.(1);Shier, Debra M.(11);Ryder, Oliver A.(1);Steiner, Cynthia C.(1).2022-08-03.GENOME BIOLOGY AND EVOLUTION

48、BCL-2 inhibitor synergizes with PI3Kδ inhibitor and overcomes FLT3 inhibitor resistance in acute myeloid leukaemia.Ming-Yue Yao(1,2,3);Ya-Fang Wang(3);Yu Zhao(3,4);Li-Jun Ling(3,4);Ye He(2);Jie Wen(6);Ming-Yue Zheng(2,5);Hua-Liang Jiang(1,2,3,4,5);Cheng-Ying Xie(2,5,7).2022-08.AMERICAN JOURNAL OF CANCER RESEARCH

49、Hormone- and antibody-mediated activation of the thyrotropin receptor.Duan, Jia(1,2);Xu, Peiyu(1,11);Luan, Xiaodong(3,4,5,6);Ji, Yujie(1,2);He, Xinheng(1,2,7);Song, Ning(2,8);Yuan, Qingning(1);Jin, Ye(3,4);Cheng, Xi(7);Jiang, Hualiang(2,7,9);Zheng, Jie(8);Zhang, Shuyang(3,4,5,6);Jiang, Yi(9,10);Xu, H. Eric(1,2,9).2022-08-01.NATURE

50、A pan-genome and chromosome-length reference genome of narrow-leafed lupin (Lupinus angustifolius) reveals genomic diversity and insights into key industry and biological traits.Garg, Gagan(1);Kamphuis, Lars G.(1,2,3);Bayer, Philipp E.(4);Kaur, Parwinder(5);Dudchenko, Olga(6,7);Taylor, Candy M.(2,5);Frick, Karen M.(1,8,9);Foley, Rhonda C.(1);Gao, Ling-Ling(1);Aiden, Erez Lieberman(5,6,7,10,11);Edwards, David(2,4);Singh, Karam B.(1,2,3).2022-08-01.PLANT JOURNAL

51、Answer for questions of repeated measurements of variance analysis and distribution test of data - Authors' reply.Wang, Dao Wen(1,2);Ni, Li(1,2);Jiang, Hualiang(3,4,5).2022-08.FRONTIERS OF MEDICINE

52、Selenium as an emerging versatile player in heterocycles and natural products modification.Hou, Wei(1);Dong, Hewei(1);Zhang, Xiang(2);Wang, Yan(3);Su, Lin(4);Xu, Hongtao(3).2022-08.DRUG DISCOVERY TODAY

53、Extracellular phosphoprotein regulation is affected by culture system scale-down.Rui, Xue(1,2);Cui, Meihua(1);Martewicz, Sebastian(1);Gagliano, Onelia(3,4);Elvassore, Nicola(1,3,4,5);Luni, Camilla(1,6,7).2022-08.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

54、Generation of two iPSC cell lines (SIAISi020-A and SIAISi019-A) from an 82-year-old mild cognitive impairment (MCI) and her unaffected child from Chinese Han population.Ding, Yanfei(1,2,3);Chen, Haijuan(1,2,3);Zhao, Jian(4,5);Wang, Ying(4,5);Deng, Yulei(1,2,3).2022-08-01.STEM CELL RESEARCH

55、Establishment of SIAISi021-A, an induced pluripotent stem cell (iPSC) line from a 71-year-old Chinese Han male with Alzheimer?s Disease (AD) having two copies of APOE4/4 allele.Ding, Yanfei(1,2,3);Chen, Haijuan(1,2,3);Zhao, Jian(4,5);Wang, Ying(4,5);Deng, Yulei(1,2,3).2022-08-01.STEM CELL RESEARCH

56、CAR-T Therapy in Clinical Practice: Technical Advances and Current Challenges.Ren, Ping(1);Zhang, Chuyue(1);Li, Wenping(1);Wang, Xian(1);Liang, Aibing(2);Yang, Guang(1);Xu, Hongtao(1);Ma, Peixiang(3,4).2022-08.ADVANCED BIOLOGY

57、Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119.Xu, Peiyu(1,8);Huang, Sijie(1,9);Guo, Shimeng(1);Yun, Ying(2);Cheng, Xi(1);He, Xinheng(1,3);Cai, Pengjun(1);Lan, Yuan(4);Zhou, Hu(1);Jiang, Hualiang(1,2,3,5,6);Jiang, Yi(5,6);Xie, Xin(1,2,5,7);Xu, H. Eric(1,3,5,7).2022-08-01.NATURE STRUCTURAL & MOLECULAR BIOLOGY

58、A Small Molecule Selected from a DNA-Encoded Library of Natural Products That Binds to TNF-alpha and Attenuates Inflammation In Vivo.Wang, Shuyue(1,2,3,4);Shi, Xiaojie(1);Li, Jie(1);Huang, Qianping(1,2,3,4);Ji, Qun(1);Yao, Ying(1,2,3,4);Wang, Tao(1,2,3,4);Liu, Lili(1);Ye, Min(5);Deng, Yun(6);Ma, Peixiang(1,7);Xu, Hongtao(1);Yang, Guang(1).2022-07-25.ADVANCED SCIENCE

59、Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer.Taromi, Sanaz(1,2);Firat, Elke(3);Simonis, Alexander(4,5);Braun, Lukas M.(1);Apostolova, Petya(1);Elze, Mirjam(6);Passlick, Bernward(6);Schumacher, Alicia(1);Lagies, Simon(7,8,16);Frey, Anna(9);Schmitt-Graeff, Annette(9);Burger, Meike(1,2);Schmittlutz, Katrin(1);Follo, Marie(1);von Elverfeldt, Dominik(10);Zhu, Xuekai(11);Kammerer, Bernd(7,8,12,16);Diederichs, Sven(6,13);Duyster, Justus(1,13);Manz, Markus G.(4,5);Niedermann, Gabriele(3,13);Zeiser, Robert(1,13,14,15).2022-07-10.CANCER LETTERS

60、A Chromosome-Length Assembly of the Hawaiian Monk Seal (Neomonachus schauinslandi): A History of Genetic Purging and Genomic Stability.Mohr, David W.(1);Gaughran, Stephen J.(2);Paschall, Justin(1);Naguib, Ahmed(3);Pang, Andy Wing Chun(3);Dudchenko, Olga(4,5);Aiden, Erez Lieberman(4,5,6,7,8);Church, Deanna M.(9);Scott, Alan F.(1).2022-07-01.GENES

61、Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer (vol 520, pg 385, 2021) (Retraction of Vol 520, Pg 385, 2021).Taromi, Sanaz(1,2);Firat, Elke(3);Simonis, Alexander(4,5);Braun, Lukas M.(1);Apostolova, Petya(1);Elze, Mirjam(6);Passlick, Bernward(6);Schumacher, Alicia(1);Lagies, Simon(7,8,9);Frey, Anna(10);Schmitt-Graeff, Annette(10);Burger, Meike(1,2);Schmittlutz, Katrin(1);Follo, Marie(1);Von Elverfeldt, Dominik(11);Zhu, Xuekai(12);Kammerer, Bernd(7,8,9);Diederichs, Sven(14,15);Duyster, Justus(14,15);Manz, Markus G.(1,4,5);Niedermann, Gabriele(13,14,15);Zeiser, Robert(1,13,16,17).2022-07-01.CANCER LETTERS

62、A Quantitative Assay for Ca2+ Uptake through Normal and Pathological Hemichannels.Nardin, Chiara(1,5);Tettey-Matey, Abraham(1);Donati, Viola(1);Marazziti, Daniela(1);Di Pietro, Chiara(1);Peres, Chiara(1);Raspa, Marcello(1);Zonta, Francesco(2);Yang, Guang(2);Gorelik, Maryna(3);Singh, Serena(3);Cardarelli, Lia(3);Sidhu, Sachdev S.(3);Mammano, Fabio(1,4).2022-07.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

63、Micropillar-based phenotypic screening platform uncovers involvement of HDAC2 in nuclear deformability.Martewicz, Sebastian(1);Zhu, Xi(1,2);Qu, Siqi(1,2);Cui, Meihua(1);Grespan, Eleonora(3);Luni, Camilla(4);Jiang, Biao(1);Yang, Guang(1);Elvassore, Nicola(1,5,6,7).2022-07.BIOMATERIALS

64、The nature of proton-coupled electron transfer in a blue light using flavin domain.Zhou, Zhongneng(1);Chen, Zijing(1);Kang, Xiu-Wen(1);Zhou, Yalin(1);Wang, Bingyao(1);Tang, Siwei(1);Zou, Shuhua(1);Zhang, Yifei(1);Hu, Qiaoyu(2,3);Bai, Fang(2,3);Ding, Bei(1);Zhong, Dongping(1,4,5,6,7,8).2022-06-28.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

65、The Anti-Glioma Effect of Juglone Derivatives through ROS Generation.Zhang, Jinsen(1,2,3,4,5);Fu, Minjie(1,2,3,4,5);Wu, Jinfeng(6);Fan, Fengfeng(1,2,3,4,5);Zhang, Xin(1,2,3,4,5);Li, Chunjie(1);Yang, Hui(1,2,3,4,5);Wu, Yonghe(7);Yin, Yiming(8);Hua, Wei(1,2,3,4,5).2022-06-14.FRONTIERS IN PHARMACOLOGY

66、SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2(ZYG)(11)(B) activity.Wang, Liying(1,4);Liu, Chao(1,4);Yang, Bo(5);Zhang, Haotian(2);Jiao, Jian(9,10);Zhang, Ruidan(4);Liu, Shujun(3);Xiao, Sai(4);Chen, Yinghong(1,4);Liu, Bo(4);Ma, Yanjie(1,4);Duan, Xuefeng(6);Guo, Yueshuai(2);Guo, Mengmeng(1,4);Wu, Bingbing(1,4);Wang, Xiangdong(9,10);Huang, Xingxu(8);Yang, Haitao(7,8);Gui, Yaoting(5);Fang, Min(6);Zhang, Luo(9,10);Duo, Shuguang(3);Guo, Xuejiang(2);Li, Wei(1,4).2022-06-08.JOURNAL OF CELL BIOLOGY

67、Dual-acting antitumor agents targeting the A 2A adenosine receptor and histone deacetylases: Design and synthesis of 4-(furan-2-yl)-1H- pyrazolo[3,4-d]pyrimidin-6-amine derivatives.Zhang, Jinfeng(1,3);Luo, Ziwei(2,3);Duan, Wenwen(1);Yang, Kexin(2,3);Ling, Lijun(2);Yan, Wenzhong(1);Liu, Ruiquan(1);Wuthrich, Kurt(1,6);Jiang, Hualiang(2,3,4);Xie, Chengying(4,5);Cheng, Jianjun(1).2022-06-05.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

68、Harnessing coronavirus spike proteins' binding affinity to ACE2 receptor through a novel baculovirus surface display system.Wang, Lin(1,2,3,4);Zhao, Lixia(1);Li, Yu(1);Ma, Peixiang(1);Kornberg, Roger D.(1,5);Nie, Yan(1).2022-05-28.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

69、Structural Insight into Molecular Inhibitory Mechanism of InsP(6) on African Swine Fever Virus mRNA-Decapping Enzyme g5Rp.Yang, Yan(1,2,3);Zhang, Changhui(1,2,3);Li, Xuehui(1,2,3);Li, Li(1,2,3);Chen, Yanjuan(1,2,3);Yang, Xin(4);Zhao, Yao(5,6);Chen, Cheng(7);Wang, Wei(4);Zhong, Zhihui(1,2,3);Yang, Cheng(1,2,3);Huang, Zhen(8);Su, Dan(1,2,3,9).2022-05-25.JOURNAL OF VIROLOGY

70、An inductive graph neural network model for compound-protein interaction prediction based on a homogeneous graph.Wan, Xiaozhe(1,2,3);Wu, Xiaolong(1,2,4);Wang, Dingyan(1,2,3);Tan, Xiaoqin(5);Liu, Xiaohong(6);Fu, Zunyun(1,2);Jiang, Hualiang(2,3,7);Zheng, Mingyue(1,2,3);Li, Xutong(1,2,3).2022-05-13.BRIEFINGS IN BIOINFORMATICS

71、Dual functions of microRNA-17 in maintaining cartilage homeostasis and protection against osteoarthritis.Zhang, Yun(1);Li, Shuaijun(2);Jin, Peisheng(3);Shang, Ting(4);Sun, Ruizhu(2);Lu, Laiya(1);Guo, Kaijin(5);Liu, Jiping(1);Tong, Yongjuan(4);Wang, Junbang(6);Liu, Sanhong(7);Wang, Chen(7);Kang, Yubin(4);Zhu, Wenmin(1);Wang, Qian(2);Zhang, Xiaoren(8);Yin, Feng(1);Sun, Yi Eve(1);Cui, Lei(1,2,4).2022-05-04.NATURE COMMUNICATIONS

72、Structures of Omicron Spike complexes and implications for neutralizing antibody development.Hangtian Guo(1,2);Yan Gao(2,3);Tinghan Li(1);Tingting Li(4,5);Yuchi Lu(6);Le Zheng(1);Yue Liu(1);Tingting Yang(1);Feiyang Luo(4,5);Shuyi Song(4,5);Wei Wang(6);Xiuna Yang(2,3);Henry C. Nguyen(7);Hongkai Zhang(2,8);Ailong Huang(9);Aishun Jin(4,5);Haitao Yang(2,3);Zihe Rao(2,10);Xiaoyun Ji(1,6).2022-05-03.CELL REPORTS

73、Discovery of ARF1-targeting inhibitor demethylzeylasteral as a potential agent against breast cancer.Chang, Jie(1,2);Yang, Ruirui(2,3,4,5);Chen, Lifan(2,3);Fan, Zisheng(1,2);Zhou, Jingyi(1,2);Guo, Hao(2,3);Zhang, Yinghui(2,3);Liu, Yadan(1,2);Zhou, Guizhen(1,2);Zhang, Keke(1,2);Chen, Kaixian(1,2,3);Jiang, Hualiang(1,2,3,5);Zheng, Mingyue(1,2,3);Zhang, Sulin(1,2,3).2022-05.ACTA PHARMACEUTICA SINICA B

74、Essential role of Cp190 in physical and regulatory boundary formation.Kaushal, Anjali(1);Dorier, Julien(2);Wang, Bihan(1);Mohana, Giriram(1);Taschner, Michael(3);Cousin, Pascal(1);Waridel, Patrice(4);Iseli, Christian(2);Semenova, Anastasiia(1);Restrepo, Simon(5);Guex, Nicolas(2);Aiden, Erez Lieberman(6,7,8,9);Gambetta, Maria Cristina(1).2022-05.SCIENCE ADVANCES

75、Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway.Jiang, Bin(1,2,3);Wang, Dongdong(1,2,3);Hu, Yunfu(1);Li, Wenxuan(1);Liu, Fengjiang(3);Zhu, Xudong(1);Li, Xiaoyu(1);Zhang, Hanwen(1);Bai, Hui(1);Yang, Qing(1);Yang, Xiuna(2);Ben, Jingjing(1);Chen, Qi(1).2022-05.MOLECULAR METABOLISM

76、Neuropilin-1-Mediated SARS-CoV-2 Infection in Bone Marrow-Derived Macrophages Inhibits Osteoclast Differentiation.Gao, Junjie(1);Mei, Hong(2,3);Sun, Jing(4);Li, Hao(1);Huang, Yuege(2,3,5,6,7);Tang, Yanhong(4);Duan, Linwei(4);Liu, Delin(8);Pang, Yidan(1);Wang, Qiyang(1);Gao, Youshui(1);Song, Ke(2,3);Zhao, Jincun(4);Zhang, Changqing(1);Liu, Jia(2,3,5,6).2022-05.ADVANCED BIOLOGY

77、PPARγ phase separates with RXRα at PPREs to regulate target gene expression.Li, Zhean(1,2);Luo, Lingling(3);Yu, Wenxia(1);Li, Ping(4);Ou, Danfeng(5);Liu, Jia(2);Ma, Hanhui(1);Sun, Qinhu(6);Liang, Aibin(4);Huang, Cheng(3);Chi, Tian(1);Huang, Xingxu(1,7);Zhang, Yu(1).2022-04-26.CELL DISCOVERY

78、Genetically based demographic reconstructions require careful consideration of generation time Response.Robinson, Jacqueline A.(1);Bowie, Rauri C. K.(2,3);Dudchenko, Olga(4,5);Aiden, Erez Lieberman(4,5,6);Hendrickson, Sher L.(7,8,9);Steiner, Cynthia C.(10);Ryder, Oliver A.(11);Mindell, David P.(3);Wall, Jeffrey D..2022-04-25.CURRENT BIOLOGY

79、Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.Yao Zhao(1,2);Yan Zhu(1,2,3);Xiang Liu(4,5);Zhenming Jin(1,2);Yinkai Duan(1,2);Qi Zhang(1,2);Chengyao Wu(1,2);Lu Feng(1,2);Xiaoyu Du(1,2);Jinyi Zhao(1,2);Maolin Shao(1,2);Bing Zhang(1,2);Xiuna Yang(1,2);Lijie Wu(6);Xiaoyun Ji(7);Luke W. Guddat(8);Kailin Yang(9);Zihe Rao(1,2,4,5,10,11);Haitao Yang(1,2,12).2022-04-19.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

80、A functional SNP rs895819 on pre-miR-27a is associated with bipolar disorder by targeting NCAM1.Yang, Yifeng(1);Lu, Wenwen(2);Ning, Mei(3,4);Zhou, Xianhao(1);Wan, Xinyao(1);Mi, Qianglong(1);Yang, Xiaoyan(2);Zhang, Di(3,4);Zhang, Yuanyuan(1);Jiang, Biao(1);He, Lin(3,4);Liu, Jia(1,2,5);Zou, Yan(2).2022-04-04.COMMUNICATIONS BIOLOGY

81、A non-canonical role for pyruvate kinase M2 as a functional modulator of Ca2+ signalling through IP3 receptors.Lavik, Andrew R.(1);McColl, Karen S.(1);Lemos, Fernanda O.(2,3);Kerkhofs, Martijn(2,3);Zhong, Fei(1);Harr, Michael(1);Schlatzer, Daniela(4);Hamada, Kozo(5);Mikoshiba, Katsuhiko(5);Crea, Francesco;Bultynck, Geert;Bootman, Martin D.(6);Parys, Jan B.(2,3);Distelhorst, Clark W.(1,7,8).2022-04.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

82、Establishment of SIAISi018-A, an induced pluripotent stem cell (iPSC) line from a healthy 45-year-old Chinese Han.Zhang, Yi(1,2,3,4);Shou, Jiajun(1,2,3,4);Gu, Wentao(1,2,3,4);Di, Weihao(5,6,7,8);Zhao, Jian(5,6,7,8);Wang, Ying(5,6,7,8);Gu, Shixin(1,2,3,4).2022-04.STEM CELL RESEARCH

83、Drug target inference by mining transcriptional data using a novel graph convolutional network framework.Zhong, Feisheng(1,2);Wu, Xiaolong(1,3);Yang, Ruirui(1,2,5,6);Li, Xutong(1,2);Wang, Dingyan(1,2);Fu, Zunyun(1,4);Liu, Xiaohong(1,5,6);Wan, XiaoZhe(1,2);Yang, Tianbiao(1,2);Fan, Zisheng(1,4);Zhang, Yinghui(1,2);Luo, Xiaomin(1,2);Chen, Kaixian(1,2);Zhang, Sulin(1,2);Jiang, Hualiang(1,2,3,5,6);Zheng, Mingyue(1,2,4).2022-04.PROTEIN & CELL

84、Graph neural network approaches for drug-target interactions.Zhang, Zehong(1,2);Chen, Lifan(1,2);Zhong, Feisheng(1,2);Wang, Dingyan(1,2);Jiang, Jiaxin(1);Zhang, Sulin(1,2);Jiang, Hualiang(1,2,3);Zheng, Mingyue(1,2);Li, Xutong(1,2).2022-04.CURRENT OPINION IN STRUCTURAL BIOLOGY

85、Establishment of SIAISi017-A, an induced pluripotent stem cell(iPSC)line from a healthy 25-year-old Chinese Hui.Zhang, Yi(1,2,3,4);Shou, Jiajun(1,2,3,4);Gu, Wentao(1,2,3,4);Di, Weihao(5,6,7,8);Zhao, Jian(5,6,7,8);Wang, Ying(5,6,7,8);Gu, Shixin(1,2,3,4).2022-04.STEM CELL RESEARCH

86、Recent advances in predicting protein–protein interactions with the aid of artificial intelligence algorithms.Li, Shiwei(1,2);Wu, Sanan(1,2);Wang, Lin(1,2);Li, Fenglei(1,2,3);Jiang, Hualiang(1,2,4);Bai, Fang(1,2,3).2022-04.CURRENT OPINION IN STRUCTURAL BIOLOGY

87、Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein.Wang, Lin(1,2);Wu, Yan(3);Yao, Sheng(4,5);Ge, Huan(6);Zhu, Ya(7);Chen, Kun(7);Chen, Wen-zhang(1);Zhang, Yi(1);Zhu, Wei(1);Wang, Hong-yang(2);Guo, Yu(8,9);Ma, Pei-xiang(1);Ren, Peng-xuan(1,2);Zhang, Xiang-lei(1,2);Li, Hui-qiong(1,2);Ali, Mohammad A.(10);Xu, Wen-qing(2);Jiang, Hua-liang(1,7);Zhang, Lei-ke(3);Zhu, Li-li(2,6);Ye, Yang(4,5);Shang, Wei-juan(3);Bai, Fang(1,2).2022-04.ACTA PHARMACOLOGICA SINICA

88、The Australian dingo is an early offshoot of modern breed dogs.Field, Matt A.(1,2);Yadav, Sonu(3);Dudchenko, Olga(4,5);Esvaran, Meera(6);Rosen, Benjamin D.(7);Skvortsova, Ksenia(2);Edwards, Richard J.(3);Keilwagen, Jens(8);Cochran, Blake J.(9);Manandhar, Bikash(9);Bustamante, Sonia(10);Rasmussen, Jacob Agerbo(11,12);Melvin, Richard G.(13);Chernoff, Barry(14,15);Omer, Arina(4);Colaric, Zane(4);Chan, Eva K. F.(2,16);Minoche, Andre E.(2);Smith, Timothy P. L.(17);Gilbert, M. Thomas P.(11,18);Bogdanovic, Ozren(2,3);Zammit, Robert A.(19);Thomas, Torsten(6);Aiden, Erez L.(4,5,20,21,22);Ballard, J. William O.(23,24).2022-04.SCIENCE ADVANCES

89、Chromosome-length genome assembly and linkage map of a critically endangered Australian bird: the helmeted honeyeater.Robledo-Ruiz, Diana A.(1);Gan, Han Ming(2,3);Kaur, Parwinder(4);Dudchenko, Olga(5,6,7);Weisz, David(5);Khan, Ruqayya(5);Aiden, Erez Lieberman(4,5,6,7,8,9);Osipova, Ekaterina(10,11,12,13);Hiller, Michael(10,11,12,13);Morales, Hernan E.(14);Magrath, Michael J. L.(15);Clarke, Rohan H.(1);Sunnucks, Paul(1);Pavlova, Alexandra(1).2022-03-29.GIGASCIENCE

90、Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure.Li, Xiaosa(1,2,3);Zhou, Lina(3,4,5,6);Gao, Bao-Qing(7);Li, Guangye(3,4,5);Wang, Xiao(3,4,5);Wang, Ying(7);Wei, Jia(7);Han, Wenyan(3,4,5);Wang, Zixian(3);Li, Jifang(3,4,5);Gao, Runze(3,4,5);Zhu, Junjie(3,4,5);Xu, Wenchao(3,4,5);Wu, Jing(3);Yang, Bei(6,8);Sun, Xiaodong(1,2);Yang, Li(9,10);Chen, Jia(3,4,6).2022-03-29.NATURE COMMUNICATIONS

91、PUMILIO proteins promote colorectal cancer growth via suppressing p21.Gong, Yuanyuan(1,2,3);Liu, Zukai(1);Yuan, Yihang(4);Yang, Zhenzhen(1);Zhang, Jiawei(1);Lu, Qin(4);Wang, Wei(1);Fang, Chao(4,5);Lin, Haifan(6);Liu, Sanhong(1,7).2022-03-25.NATURE COMMUNICATIONS

92、Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue.Wang, Haofeng(1,2,3,4);Xiao, Yunjie(1,2,3,4,5);Chen, Xia(1);Zhang, Mengwen(6,7);Sun, Guangxin(6);Wang, Feng(1);Wang, Lin(2,3,4);Zhang, Hanxiao(1);Zhang, Xiaoyu(1,8,9);Yang, Xin(5);Li, Wenling(1);Wei, Yi(1);Yao, Deqiang(10);Zhang, Bing(2,3);Li, Jun(2,3);Cui, Wen(1,5);Wang, Fenghua(1);Chen, Cheng(1);Shen, Wei(2,3,4);Su, Dan(11,12,13);Bai, Fang(2,3,4);Huang, Jinhai(1);Ye, Sheng(1);Zhang, Lei(1);Ji, Xiaoyun(14);Wang, Wei(5);Wang, Zefang(1,9);Hochstrasser, Mark(6);Yang, Haitao(1,2,3,4,9).2022-03-25.NATURE COMMUNICATIONS

93、Incorporating Selenium into Heterocycles and NaturalProducts-From Chemical Properties to Pharmacological Activities br.Hou, Wei(1,2);Xu, Hongtao(3).2022-03-24.JOURNAL OF MEDICINAL CHEMISTRY

94、KPT330 improves Cas9 precision genome- and base-editing by selectively regulating mRNA nuclear export.Cui, Yan ru(1);Wang, Shao jie(1);Ma, Tiancheng(2);Yu, Peihong(1,3);Chen, Jun(4);Guo, Taijie(2);Meng, Genyi(2);Jiang, Biao(1);Dong, Jiajia(2);Liu, Jia(1,5,6,7).2022-03-17.COMMUNICATIONS BIOLOGY

95、Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors.Duan, Jia(1,2);Shen, Dan Dan(3);Zhao, Tingting(4,5);Guo, Shimeng(4,5);He, Xinheng(1,2);Yin, Wanchao(1);Xu, Peiyu(1);Ji, Yujie(1,2);Chen, Li Nan(3);Liu, Jinyu(4,5);Zhang, Huibing(3);Liu, Qiufeng(1);Shi, Yi(1);Cheng, Xi(1);Jiang, Hualiang(1,2,6);Eric Xu, H.(1,2,6);Zhang, Yan(3,7,8,9);Xie, Xin(1,4,5,10,11);Jiang, Yi(1,6,12).2022-03-15.NATURE COMMUNICATIONS

96、Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody.Yin, Wanchao(1);Xu, Youwei(1);Xu, Peiyu(1);Cao, Xiaodan(2);Wu, Canrong(1);Gu, Chunyin(2);He, Xinheng(1,3);Wang, Xiaoxi(1);Huang, Sijie(1);Yuan, Qingning(4);Wu, Kai(4);Hu, Wen(4);Huang, Zifu(5);Liu, Jia(2);Wang, Zongda(2);Jia, Fangfang(2);Xia, Kaiwen(2);Liu, Peipei(2);Wang, Xueping(2);Song, Bin(6);Zheng, Jie(6);Jiang, Hualiang(3,5,7);Cheng, Xi(3,5);Jiang, Yi(1,3,5);Deng, Su-Jun(2);Xu, H. Eric(1,3,7).2022-03-04.SCIENCE

97、Chromosome size affects sequence divergence between species through the interplay of recombination and selection.Tigano, Anna(1,2,3);Khan, Ruqayya(4);Omer, Arina D.(4);Weisz, David(4);Dudchenko, Olga(4,5);Multani, Asha S.(6);Pathak, Sen(6);Behringer, Richard R.(6);Aiden, Erez L.(4,5,7,8,9);Fisher, Heidi(10);MacManes, Matthew D.(1,2).2022-03-01.EVOLUTION

98、The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals.Wang, Fenghua(1,2,3);Chen, Cheng(1,2);Wang, Zefang(1,2);Han, Xu(1);Shi, Peidian(1);Zhou, Kaixuan(2);Liu, Xiaomei(2);Xiao, Yunjie(1);Cai, Yan(2);Huang, Jinhai(1);Zhang, Lei(1);Yang, Haitao(1,2,4,5).2022-03.VIRUSES-BASEL

99、Facing small and biased data dilemma in drug discovery with enhanced federated learning approaches.Xiong, Zhaoping(1,2,3,4);Cheng, Ziqiang(1,2,5);Lin, Xinyuan(6);Xu, Chi(6);Liu, Xiaohong(1,2,3);Wang, Dingyan(3,4);Luo, Xiaomin(3);Zhang, Yong(6);Jiang, Hualiang(1,2,3);Qiao, Nan(6);Zheng, Mingyue(3).2022-03.SCIENCE CHINA-LIFE SCIENCES

100、Commercially derived versatile optical architecture for two-photon STED, wavelength mixing and label-free microscopy.Peres, Chiara(1,2);Nardin, Chiara(1);Yang, Guang(3);Mammano, Fabio(1,2,3).2022-03-01.BIOMEDICAL OPTICS EXPRESS

101、Cell-Cell Communication Alterations via Intercellular Signaling Pathways in Substantia Nigra of Parkinson's Disease.Huang, Maoxin(1,2);Xu, Liang(3);Liu, Jin(1,2);Huang, Pei(1,2);Tan, Yuyan(1,2);Chen, Shengdi(1,2,4).2022-02-25.FRONTIERS IN AGING NEUROSCIENCE

102、Target-Based Virtual Screening and LC/MS-Guided Isolation Procedure for Identifying Phloroglucinol-Terpenoid Inhibitors of SARS-CoV-2.Hou, Bo(1,2);Zhang, Yu-Min(3);Liao, Han-Yi(4);Fu, Li-Feng(4);Li, De-Dong(4);Zhao, Xin(4);Qi, Jian-Xun(4);Yang, Wei(4);Xiao, Geng-Fu(3);Yang, Lian(1,2);Zuo, Zheng-Yu(1,2);Wang, Lin(5,6);Zhang, Xiang-Lei(5,6);Bai, Fang(5,6);Yang, Liu(1,2);Gao, George F.(4);Song, Hao(4,7);Hu, Jiang-Miao(1,2);Shang, Wei-Juan(3);Zhou, Jun(1,2).2022-02-25.JOURNAL OF NATURAL PRODUCTS

103、Probing the Allosteric Inhibition Mechanism of a Spike Protein Using Molecular Dynamics Simulations and Active Compound Identifications.Wang, Qian(4,5);Wang, Lin(1,2);Zhang, Yumin(3);Zhang, XiangLei(1,2);Zhang, Leike(3);Shang, Weijuan(3);Bai, Fang(1,2).2022-02-24.JOURNAL OF MEDICINAL CHEMISTRY

104、Calcium Homeostasis in the Epididymal Microenvironment: Is Extracellular Calcium a Cofactor for Matrix Gla Protein-Dependent Scavenging Regulated by Vitamins.Shum, Winnie(1,2);Zhang, Bao Li(1,2,3);Cao, Albert Shang(1);Zhou, Xin(1);Shi, Su Meng(1);Zhang, Ze Yang(1);Gu, Lou Yi(1);Shi, Shuo(4).2022-02-17.FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

105、A VDAC1-mediated NEET protein chain transfers [2Fe-2S] clusters between the mitochondria and the cytosol and impacts mitochondrial dynamics.Karmi, Ola(1,2,3);Marjault, Henri-Baptiste(1,2);Bai, Fang(4,5,6,7,8);Roy, Susmita(9);Sohn, Yang-Sung(1,2);Yahana, Merav Darash(1,2);Morcos, Faruck(10,11);Ioannidis, Konstantinos(1,2,12);Nahmias, Yaakov(1,2,12);Jennings, Patricia A.(13);Mittler, Ron(3);Onuchic, Jose N.(4,5,6);Nechushtai, Rachel(1,2).2022-02-15.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

106、Cell-Penetrating Botulinum Neurotoxin Type A With Improved Cellular Uptake and Therapeutic Index.Wei, Xuan(1);Li, Lu(1);Wu, Yiwen(2);Liu, Jia(1,3).2022-02-11.FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY

107、Metal-Catalyzed One-Pot On-DNA Syntheses of Diarylmethane and Thioether Derivatives.Ma, Fei(1,2);Li, Jie(1);Zhang, Shuning(1);Gu, Yuang(1);Tan, Tingting(1);Chen, Wanting(1);Wang, Shuyue(1);Xu, Hongtao(1);Yang, Guang(1);Lerner, Richard A.(3).2022-02-04.ACS CATALYSIS

108、Detection of Pathological Markers of Neurodegenerative Diseases following Microfluidic Direct Conversion of Patient Fibroblasts into Neurons.Mollinari, Cristiana(1,2);De Dominicis, Chiara(1,3);Lupacchini, Leonardo(4);Sansone, Luigi(4);Caprini, Davide(5);Casciola, Carlo Massimo(6);Wang, Ying(7,8);Zhao, Jian(7,8);Fini, Massimo(4);Russo, Matteo(4,9);Garaci, Enrico(4,10);Merlo, Daniela(1).2022-02-01.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

109、Glutamine synthetase licenses APC/C-mediated mitotic progression to drive cell growth.Zhao, Jiang-Sha(1,2,3);Shi, Shuo(4);Qu, Hai-Yan(1,2);Keckesova, Zuzana(5);Cao, Zi-Jian(2);Yang, Li-Xian(2);Yu, Xiaofu(6);Feng, Limin(1,2);Shi, Zhong(7);Krakowiak, Joanna(8);Mao, Ruo-Ying(1,2);Shen, Yi-Tong(2);Fan, Yu-Meng(2);Fu, Tian-Min(9);Ye, Cunqi(10);Xu, Daqian(1,2,3);Gao, Xiaofei(11);You, Jia(11);Li, Wenbo(8,12);Liang, Tingbo(1,2,3);Lu, Zhimin(1,2,3);Feng, Yu-Xiong(1,2,3).2022-02-01.NATURE METABOLISM

110、Chromosome-level genome of Schistosoma haematobium underpins genome-wide explorations of molecular variation.Stroehlein, Andreas J.(1);Korhonen, Pasi K.(1);Lee, V. Vern(2);Ralph, Stuart A.(2);Mentink-Kane, Margaret(3);You, Hong(4);McManus, Donald P.(4);Tchuente, Louis-Albert Tchuem(5,6);Stothard, J. Russell(6);Kaur, Parwinder(7);Dudchenko, Olga(8,9);Aiden, Erez Lieberman(7,8,9,10,11);Yang, Bicheng(12);Yang, Huanming(13,14);Emery, Aidan M.(15,16);Webster, Bonnie L.(15,16);Brindley, Paul J.(17);Rollinson, David(15,16);Chang, Bill C. H.(1);Gasser, Robin B.(1);Young, Neil D.(1).2022-02-01.PLOS PATHOGENS

111、Multi-instance learning of graph neural networks for aqueous pK(a) prediction.Xiong, Jiacheng(1,2);Li, Zhaojun(3);Wang, Guangchao(4);Fu, Zunyun(1);Zhong, Feisheng(1,2);Xu, Tingyang(5);Liu, Xiaomeng(1,2);Huang, Ziming(1,2);Liu, Xiaohong(1,3,6,7);Chen, Kaixian(1,2);Jiang, Hualiang(1,2,6,7);Zheng, Mingyue(1,2).2022-02-01.BIOINFORMATICS

112、Systematic Investigation of the Effects of Multiple SV40 Nuclear Localization Signal Fusion on the Genome Editing Activity of Purified SpCas9.Shui, Sailan(1);Wang, Shaojie(1,2,3);Liu, Jia(1).2022-02.BIOENGINEERING-BASEL

113、Rhodium(III) Catalyzed C(p(3))-H Functionalization.Han Gaoxu(1);Xu Hongtao(2);Hou Wei(1).2022-02.有机化学

114、A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors.Ren, Peng-xuan(1,2);Shang, Wei-juan(3);Yin, Wan-chao(4);Ge, Huan(5);Wang, Lin(1,2);Zhang, Xiang-lei(1,2);Li, Bing-qian(1,2,6);Li, Hong-lin(5);Xu, Ye-chun(4,7);Xu, Eric H.(4,7);Jiang, Hua-liang(1,2,4,7);Zhu, Li-li(5);Zhang, Lei-ke(3);Bai, Fang(1,2).2022-02.ACTA PHARMACOLOGICA SINICA

115、High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases.Xiao, Senhao(1,2,3);Guo, Siqi(1,5);Han, Jie(1);Sun, Yanli(1,6,7);Wang, Mingchen(1,2,3);Chen, Yantao(1);Fang, Xueyu(1,2,3);Yang, Feng(1);Mu, Yajuan(8);Zhang, Liang(8);Ding, Yiluan(3,4);Zhang, Naixia(3,4);Jiang, Hualiang(1,2,3);Chen, Kaixian(1,2,3);Zhao, Kehao(6,7);Luo, Cheng(1,2,3,9);Chen, Shijie(1,3,9,10).2022-01-25.NUCLEIC ACIDS RESEARCH

116、Structural Basis of Zika Virus Helicase in RNA Unwinding and ATP Hydrolysis.Lin, Mengmeng(1,2,3,4);Cui, Wen(1,5);Tian, Hongliang(1);Zhang, Yan(1);Chen, Chen(1);Yang, Xiaoyun(1);Chi, Heng(1);Mu, Zhongyu(1);Chen, Cheng(1);Wang, Zefang(1,6);Ji, Xiaoyun(7);Yang, Haitao(1,2,3,4,6);Lin, Zhi(1).2022-01-14.ACS INFECTIOUS DISEASES

117、Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation.Tan, Xiaoqin(1,2);Li, Chunpu(3,4);Yang, Ruirui(1,5,6,7);Zhao, Sen(3);Li, Fei(8);Li, Xutong(1,5);Chen, Lifan(1,5);Wan, Xiaozhe(1,5);Liu, Xiaohong(1,6,7);Yang, Tianbiao(1,4);Tong, Xiaochu(1,5);Xu, Tingyang(9);Cui, Rongrong(1,10);Jiang, Hualiang(1,4,5,6,7);Zhang, Sulin(1);Liu, Hong(3,4);Zheng, Mingyue(1,4,5).2022-01-13.JOURNAL OF MEDICINAL CHEMISTRY

118、Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1-Nup98 Complex to Compete With mRNA Nuclear Export.Li, Tinghan(1);Wen, Yibo(1);Guo, Hangtian(1);Yang, Tingting(1);Yang, Haitao(2,3,4,5,6);Ji, Xiaoyun(1,7).2022-01-12.FRONTIERS IN MOLECULAR BIOSCIENCES

119、Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.Qiang, Min(1);Ma, Peixiang(1);Li, Yu(1,2,3,4);Liu, Hejun(5);Harding, Adam(6);Min, Chenyu(7);Wang, Fulian(1,2,3,4);Liu, Lili(1);Yuan, Meng(5);Ji, Qun(1);Tao, Pingdong(1,2,3,4);Shi, Xiaojie(1);Li, Zhean(1);Li, Teng(1,2,3,4);Wang, Xian(1,2,3,4);Zhang, Yu(2);Wu, Nicholas C.(5);Lee, Chang-Chun D.(5);Zhu, Xueyong(5);Gilbert-Jaramillo, Javier(6);Zhang, Chuyue(1,2,3,4);Saxena, Abhishek(1);Huang, Xingxu(2);Wang, Hou(8);James, William(6);Dwek, Raymond A.(9);Wilson, Ian A.(5,10);Yang, Guang(1,7);Lerner, Richard A.(11).2022-01-05.ADVANCED SCIENCE

120、Structure of the NuA4 histone acetyltransferase complex.Liting Ji(1);Lixia Zhao(1);Ke Xu(1);Huihan Gao(1);Yang Zhou(1);Roger D. Kornberg(2);Heqiao Zhang(1).2022.PNAS

121、IKZF3 deficiency potentiates chimeric antigen receptor T cells targeting solid tumors.Zou, Yan(1);Liu, Bo(2,3);Li, Long(1);Yin, Qinan(4);Tang, Jiaxing(1);Jing, Zhengyu(2,3);Huang, Xingxu(2);Zhu, Xuekai(1);Chi, Tian(2,5).2022.CANCER LETTERS

122、CD40L-armed oncolytic herpes simplex virus suppresses pancreatic ductal adenocarcinoma by facilitating the tumor microenvironment favorable to cytotoxic T cell response in the syngeneic mouse model.Wang, Ruikun(1,2);Chen, Jingru(1,3);Wang, Wei(4);Zhao, Zhuoqian(1);Wang, Haoran(1);Liu, Shiyu(1,5,6);Li, Fan(1,5,6);Wan, Yajuan(1);Yin, Jie(7);Wang, Rui(1);Li, Yuanke(5,6);Zhang, Cuizhu(1,3);Zhang, Hongkai(1,2,4,5,6,8);Cao, Youjia(1,2,3).2022-01.JOURNAL FOR IMMUNOTHERAPY OF CANCER

123、The Life of SARS-CoV-2 Inside Cells: Replication-Transcription Complex Assembly and Function.Lou, Zhiyong(1);Rao, Zihe(1,2,3,4,5,6,7,8).2022.ANNUAL REVIEW OF BIOCHEMISTRY

124、Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson's Disease: Past, Present, and Future.Tan, Yu-Yan(1,2);Jenner, Peter(3);Chen, Sheng-Di(1,2,4).2022.JOURNAL OF PARKINSONS DISEASE

125、The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while bone.Zhang, Shaoqing(1);Chen, Yue(1);Xu, Zhongli(2);Yang, Jun(1);Sun, Renhong(3);Wang, Juan(1);Sun, Yiming(4);Jiang, Biao(2);Yang, Xiaobao(2,3);Tan, Wenfu(1).2022.THERANOSTICS

126、BCL-2 inhibitor synergizes with PI3K delta inhibitor and overcomes FLT3 inhibitor resistance in acute myeloid leukaemia.Yao, Ming-Yue(1,2,3,4);Wang, Ya-Fang(3);Zhao, Yu(3,4);Ling, Li-Jun(3,4);He, Ye(2);Wen, Jie(6);Zheng, Ming-Yue(2,5);Jiang, Hua-Liang(1,2,3,4,5);Xie, Cheng-Ying(2,5,7).2022.AMERICAN JOURNAL OF CANCER RESEARCH

127、Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway.Li, Qian(1);Tan, Jia-Xin(1);He, Yong(2);Bai, Fang(3,4);Li, Shi-Wei(3,4);Hou, Yi-Wen(1);Ji, Long-Shan(1);Gao, Ya-Ting(1);Zhang, Xin(1);Zhou, Zhen-Hua(5);Yu, Zhuo(5);Fang, Miao(1);Gao, Yue-Qiu(1);Li, Man(1).2022.INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES

128、Self-assembly of X-shaped antibody to combine the activity of IgG and IgA for enhanced tumor killing.Liang, Yuexi(1,2,3);Li, Xin(1,2,3);Peng, Fengping(5);Ye, Xiaohan(1,2,3);Wang, Wei(4);Cen, Tianyi(1,2,3);Li, Fan(1,2,3);Lu, Yue(1,2);Liu, Zhaoyun(5);Liu, Hui(5);Ding, Kai(5);Ye, Kai(1,2,3);Yu, Yang(1,2,3);Ma, Tianyu(1,2,3);Zhang, Sihe(6);Huang, Yi(7);Wang, Yuan(1,2,3);Yang, Xue(1,2);Fu, Rong(5);Zhang, Hongkai(1,2,3,4).2022.THERANOSTICS

129、Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB.Shan Sun(1,6,7);Yan Gao(1);Xiaolin Yang(1);Xiuna Yang(1,8);Tianyu Hu(1);Jingxi Liang(2);Zhiqi Xiong(3);Yuting Ran(1);Pengxuan Ren(1);Fang Bai(1);Luke W. Guddat(5);Haitao Yang(1,8);Zihe Rao(1,2,3,4,8);Bing Zhang(1,8).2022.PROTEIN & CELL

130、Hinge region mediates signal transmission of luteinizing hormone and chorionic gonadotropin receptor.He, Xinheng(1,2);Duan, Jia(1,2);Ji, Yujie(1,2);Zhao, Lifen(1);Jiang, Hualiang(1,2,3,4,5);Jiang, Yi(4,5);Eric Xu, H.(1,2);Cheng, Xi(1,2,3).2022-01.COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL

131、Metabolic adaptation to the chronic loss of Ca2+ signaling induced by KO of IP3 receptors or the mitochondrial Ca2+ uniporter.Young, Michael P.(1);Schug, Zachary T.(2);Booth, David M.(1);Yule, David, I(3);Mikoshiba, Katsuhiko(4,5);Hajnoczky, Gyorgy(1);Joseph, Suresh K.(1).2022.JOURNAL OF BIOLOGICAL CHEMISTRY

132、Full-length TprK of Treponema pallidum subsp. pallidum in lipid nanodiscs is a monomeric porin.Lian, Tingting(1);Zhang, Bing(2,3);Giacani, Lorenzo(4,5);Kou, Caixia(1);Yang, Xiuna(2,3);Zhang, Ruili(6);Wang, Qianqiu(1).2022-01.ENZYME AND MICROBIAL TECHNOLOGY

133、CRISPR-surfaceome: An online tool for designing highly efficient sgRNAs targeting cell surface proteins.Mei, Hong(1);Gu, Qian(1,2,3);Wang, Wei(1);Meng, Yu(1,2,3);Jiang, Lichun(1);Liu, Jia(1,2,3,4,5).2022-01.COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL

134、Loss of inhibitory function from the zeta subunit of the F1FO-ATPase of Sinorhizobium meliloti a symbiotic alpha-proteobacteria.Mendoza-Hoffmann, Francisco(1);Yang, Lingyun(2);Buratto, Damiano(3);Garcia-Trejo, Jose J.(4).2022-09-01.BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

135、A history of the origin and development of Japanese Society for Neurochemistry and international cooperation and contribution.Mikoshiba, Katsuhiko(1,2).2022-08-01.JOURNAL OF NEUROCHEMISTRY

2021

1. A Novel AKR1C3   Specific Prodrug TH3424 With Potent Antitumor Activity in Liver Cancer. He,   Ping(1,2);Wang, Chunnian(3);Wang, Yanlan(1,2);Wang, Caiyan(4);Zhou,   Changhua(1,2);Cao, Donglin(5);Li, Jiang(6);Bushnell, David A.(7);Li,   Qing(1,2);Kornberg, Roger D.(2,7);Xie, Wei(2,8);Wang, Zhong(1,2). 2021-07.   CLINICAL PHARMACOLOGY & THERAPEUTICS10.1002/cpt.2171·

2. A Peptide Binder of E3 Ligase Adaptor   SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells.   Wang, Zhen(1,2);Zhang, Hao(2,3);Chen, Baoen(2);Ouyang, Sisheng(2);Zheng,   Tong(2);Zhou, Ran(2,3);Dong, Ze(2);Huang, Yue(2,4);Zhang, Tao(2);Jiang,   Hualiang(2,3,4,5);Gan, Jianhua(6);Luo, Cheng(1,2,3,4);Yang,   Cai-Guang(1,2,3,4). 2021-02. CHINESE JOURNAL OF   CHEMISTRY10.1002/cjoc.202000462

3. Active Learning for Drug Design: A Case   Study on the Plasma Exposure of Orally Administered Drugs. Ding,   Xiaoyu(1,2);Cui, Rongrong(3);Yu, Jie(1,2);Liu, Tiantian(1,2);Zhu,   Tingfei(1,2);Wang, Dingyan(1,2);Chang, Jie(3);Fan, Zisheng(3);Liu,   Xiaomeng(1,2);Chen, Kaixian(1,2,3);Jiang, Hualiang(1,2,3,4);Li,   Xutong(1,2);Luo, Xiaomin(1,2);Zheng, Mingyue(1,2,3). 2021-11-25. JOURNAL OF   MEDICINAL CHEMISTRY10.1021/acs.jmedchem.1c01683

4. Antivirals with common targets against   highly pathogenic viruses. Lu Lu;Su Shan;Yang Haitao;Jiang Shibo. 2021-03-18.   CELL10.1016/j.cell.2021.02.013

5. Architecture of the mycobacterial   succinate dehydrogenase with a membrane-embedded Rieske FeS cluster. Zhou,   Xiaoting;Gao, Yan;Wang, Weiwei;Yang, Xiaolin;Yang, Xiuna;Liu, Fengjiang;Tang,   Yanting;Lam, Sin Man;Shui, Guanghou;Yu, Lu;Tian, Changlin;Guddat, Luke   W.;Wang, Quan;Rao, Zihe;Gong, Hongri. 2021-04-05. PROCEEDINGS OF THE NATIONAL   ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA10.1073/pnas.2022308118

6. Astrocytic IP(3)Rs: Beyond IP(3)R2.   Sherwood, Mark W.(1);Arizono, Misa(2);Panatier, Aude(1);Mikoshiba,   Katsuhiko(3,4,5);Oliet, Stephane H. R.(1). 2021-07-30. FRONTIERS IN CELLULAR   NEUROSCIENCE10.3389/fncel.2021.695817

7. Astrocytic STAT3 activation and chronic   itch require IP3R1/TRPC-dependent Ca21 signals in mice. Shiratori-Hayashi,   Miho(1);Yamaguchi, Chiharu(1);Eguchi, Kazushi(1);Shiraishi, Yuto(1);Kohno,   Keita(1);Mikoshiba, Katsuhiko(4,5,6);Inoue, Kazuhide(2);Nishida,   Motohiro(3,7,8);Tsuda, Makoto(1). 2021-04. JOURNAL OF ALLERGY AND CLINICAL   IMMUNOLOGY10.1016/j.jaci.2020.06.039

8. Bcl-xL acts as an inhibitor of IP3R   channels, thereby antagonizing Ca2+-driven apoptosis. Rosa,   Nicolas(1,2);Ivanova, Hristina(1,2);Wagner, Larry E.(3);Kale, Justin(4);La   Rovere, Rita(1,2);Welkenhuyzen, Kirsten(1,2);Louros, Nikolaos(5,6);Karamanou,   Spyridoula(7);Shabardina, Victoria(8);Lemmens, Irma(9,10);Vandermarliere,   Elien(11);Hamada, Kozo(12);Ando, Hideaki(13);Rousseau,   Frederic(5,6);Schymkowitz, Joost(5,6);Tavernier, Jan(9,10);Mikoshiba,   Katsuhiko(12,14);Economou, Anastassios(7);Andrews, David W.(4);Parys, Jan   B.(1,2);Yule, David, I(3);Bultynck, Geert(1,2). 2021. CELL DEATH AND   DIFFERENTIATION10.1038/s41418-021-00894-w

9. Both IRBIT and long-IRBIT bind to and   coordinately regulate Cl-/HCO3- exchanger AE2 activity through modulating the   lysosomal degradation of AE2. Itoh, Ryo(1);Hatano, Naoya(2);Murakami,   Momoko(1);Mitsumori, Kosuke(1);Kawasaki, Satoko(1);Wakagi, Tomoka(1);Kanzaki,   Yoshino(1);Kojima, Hiroyuki(1);Kawaai, Katsuhiro(3);Mikoshiba,   Katsuhiko(4);Hamada, Koichi(1);Mizutani, Akihiro(1). 2021-03-16. SCIENTIFIC   REPORTS10.1038/s41598-021-85499-6

10. Characterization of a New Impurity in   Metaraminol Bitartrate for Injec-tion by 2D HPLC-Q/TOF-MS, Chemical Synthesis   and NMR. Luo, Wenyan(1,2);Zhang, Hanzhi(2);Sun, Ning(3);Qin, Feng(2,4,5);Liu,   Hao(2). 2021. CURRENT PHARMACEUTICAL ANALYSIS10.2174/1573412917999201102211507

11. Circulating miR-221/222 reduces CD4(+) T   cells by inhibiting CD4 expression in colorectal cancer. Hu, Jiajia(1);Zhang,   Jiawei(2);Yu, Meng(3);Liu, Zukai(2);Zou, Yan(2);Hong, Liwen(4);Zhang,   Tianyu(4);Sun, Jing(5);Zheng, Minhua(5);Zhu, Xuekai(2);Wang, Zhengting(4);Liu,   Sanhong(6). 2021-10. ACTA BIOCHIMICA ET BIOPHYSICA SINICA10.1093/abbs/gmab106

12. CKB inhibits epithelial-mesenchymal   transition and prostate cancer progression by sequestering and inhibiting AKT   activation. Wang, Zheng(1);Hulsurkar, Mohit(1,2);Zhuo, Lijuan(1,3);Xu,   Jinbang(1,4);Yang, Han(1);Naderinezhad, Samira(1,2);Wang, Lin(5);Zhang,   Guoliang(1,6);Ai, Nanping(1);Li, Linna(1);Chang, Jeffrey T.(7);Zhang,   Songlin(8);Fazli, Ladan(9,10);Creighton, Chad J.(11,12);Bai, Fang(5);Ittmann,   Michael M.(13,14);Gleave, Martin E.(9,10);Li, Wenliang(1,2). 2021.   NEOPLASIA10.1016/j.neo.2021.09.005

13. Combination of Derivatization-HPLC-MS   and Enzymatic Hydrolysis-Edman Degradation for Amino Acid Sequence and   Configuration of Polymyxin B Components. Zhang, Hanzhi(1,2);Li, Feng(3);Dun,   Junling(4);Sun, Ning(5);Liu, Hao(1);Chen, Guiliang(6). 2021-11. CHROMATOGRAPHIA10.1007/s10337-021-04091-2

14. Connexin Hemichannel Activation by   S-Nitrosoglutathione Synergizes Strongly with Photodynamic Therapy   Potentiating Anti-Tumor Bystander Killing. Nardin, Chiara(1);Peres,   Chiara(1);Putti, Sabrina(1);Orsini, Tiziana(1);Colussi,   Claudia(2,3);Mazzarda, Flavia(1,4);Raspa, Marcello(1);Scavizzi,   Ferdinando(1);Salvatore, Anna Maria(1);Chiani, Francesco(1);Tettey-Matey,   Abraham(1);Kuang, Yuanyuan(5);Yang, Guang(5);Retamal, Mauricio A.(6);Mammano,   Fabio(1,7). 2021. CANCERS10.3390/cancers13205062

15. CRISPR/Cas12a-assisted rapid   identification of key beer spoilage bacteria. Meng, Qingzhou(1);Yang,   Hongmei(2);Zhang, Guiquan(3,4);Sun, Wenjun(5);Ma, Peixiang(6);Liu,   Xinyi(7);Dang, Lu(8);Li, Guanglei(5);Huang, Xingxu(5);Wang, Xinjie(9);Liu,   Jianghuai(3,4);Leng, Qibin(1). 2021-12. INNOVATIVE FOOD SCIENCE &   EMERGING TECHNOLOGIES10.1016/j.ifset.2021.102854

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19. Discovery of a Potent and Selective FLT3   Inhibitor   (Z)-N-(5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-4-methyl-1H-pyrrol-3-yl)-3-(pyrrolidin-1-yl)propanamide   with Improved Drug-like Properties and Superior Efficacy in FLT3-ITD-Positive   Acute Myeloid Leukemia. Wang, Junwei(1);Pan, Xiang(1);Song, Yi(1);Liu,   Jian(1);Ma, Fei(2);Wang, Ping(1);Liu, Yan(1);Zhao, Lin(1);Kang, Di(1);Hu,   Lihong(1). 2021-04-22. JOURNAL OF MEDICINAL   CHEMISTRY10.1021/acs.jmedchem.0c02247

20. Diversified strategy for the synthesis   of DNA-encoded oxindole libraries. Wang, Xuan(1,2);Liu, Jiaxiang(1);Yan,   Ziqin(1);Liu, Xiaohong(3,4,5);Liu, Sixiu(1);Suo, Yanrui(1);Lu, Weiwei(1);Yue,   Jinfeng(1);Chen, Kaixian(3,4,5);Jiang, Hualiang(3,4,5);Zhao, Yujun(1);Zheng,   Mingyue(4,5);Dai, Dongcheng(2);Lu, Xiaojie(1). 2021-02-28. CHEMICAL   SCIENCE10.1039/d0sc06696f

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23. Gem-Difluorocyclopropenes as Versatile   β-Monofluorinated Three-sp2Carbon Sources for Cp*Rh(III)-Catalyzed [4 + 3]   Annulation: Experimental Development and Mechanistic Insight. Xu,   Huiying(1,2,3);Chen, Weijie(1,2,3);Bian, Mengyao(1,2,3);Xu, Hongtao(4,5);Gao,   Hui(1,2,3);Wang, Ting(1,2,3);Zhou, Zhi(1,2,3);Yi, Wei(1,2,3). 2021-12-03. ACS   CATALYSIS10.1021/acscatal.1c04508

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51. Accurate Retention Time Prediction Based   on Monolinked Peptide Information to Confidently Identify Cross-Linked   Peptides. Huang, Rong(1,2);Zhu, Wei(1);Xu, Zili(1);Chen, Jiakang(1);Jiang,   Biao(1);Chen, Hongli(1);Chen, Wenzhang(1). 2021-09-01. JOURNAL OF THE   AMERICAN SOCIETY FOR MASS SPECTROMETRY10.1021/jasms.1c00120

52. Assessing SIRAH's Capability to Simulate   Intrinsically Disordered Proteins and Peptides. Klein,   Florencia(1,2);Barrera, Exequiel E.(1,3);Pantano, Sergio(1,4). 2021-02-09.   JOURNAL OF CHEMICAL THEORY AND COMPUTATION10.1021/acs.jctc.0c00948

53. Avidity-Based Selection of   Tissue-Specific CAR-T Cells from a Combinatorial Cellular Library of CARs.   Ma, Peixiang(1);Ren, Ping(1);Zhang, Chuyue(1,2,3,4);Tang,   Jiaxing(1,2,3,4);Yu, Zheng(1);Zhu, Xuekai(1);Fan, Kun(1,2,3,4);Li,   Guanglei(2);Zhu, Wei(1);Sang, Wei(5);Min, Chenyu(6);Chen, Wenzhang(1);Huang,   Xingxu(2);Yang, Guang(1);Lerner, Richard A.(7). 2021-03. ADVANCED   SCIENCE10.1002/advs.202003091

54. BAY 60-6583 Enhances the Antitumor   Function of Chimeric Antigen Receptor-Modified T Cells Independent of the   Adenosine A2b Receptor. Tang, Jiaxing(1,2,3,4);Zou, Yan(1);Li, Long(1);Lu,   Fengping(1);Xu, Hongtao(1);Ren, Pengxuan(1);Bai, Fang(1);Niedermann, Gabriele(5,6,7);Zhu,   Xuekai(1). 2021-03-12. FRONTIERS IN PHARMACOLOGY10.3389/fphar.2021.619800

55. Characterizing disease progression of   nonalcoholic steatohepatitis in Leptin-deficient rats by integrated   transcriptome analysis. Lu, Ping(1,2);Yang, Guang(3);Jiang, Lichun(4);He,   Wen(1,2);Wu, Wanwan(5);Qi, Lingbin(1,2);Shen, Shijun(3);Rao, Junhua(6);Zhang,   Peng(5);Xue, Zhigang(1,2);Jiang, Cizhong(3,7);Fan, Guoping(4,8);Zhu,   Xianmin(4,5). 2021-03. EXPERIMENTAL BIOLOGY AND   MEDICINE10.1177/1535370220976530

56. Chromosome-length genome assembly and   structural variations of the primal Basenji dog (Canis lupus familiaris)   genome. Edwards, Richard J.(1);Field, Matt A.(2,3);Ferguson, James   M.(4);Dudchenko, Olga(5,6,7);Keilwagen, Jens(8);Rosen, Benjamin D.(9);Johnson,   Gary S.(10);Rice, Edward S.(11);Hillier, La Deanna(12);Hammond, Jillian   M.(4);Towarnicki, Samuel G.(1);Omer, Arina(5,6);Khan,   Ruqayya(5,6);Skvortsova, Ksenia(13,14);Bogdanovic, Ozren(1,13);Zammit, Robert   A.(15);Aiden, Erez Lieberman(5,6,7,16,17);Warren, Wesley C.(18);Ballard, J.   William O.(19,20). 2021. BMC GENOMICS10.1186/s12864-021-07493-6

57. Click Chemistry in Natural Product   Modification. Zhang, Xiang(1);Zhang, Shuning(2);Zhao, Songfeng(1);Wang,   Xuan(3);Liu, Bo(3);Xu, Hongtao(2). 2021-11-17. FRONTIERS IN   CHEMISTRY10.3389/fchem.2021.774977

58. Combretastatin A4-derived payloads for   antibody-drug conjugates. Huang Rong(1,2);Shen, Yao(1);Xu, Zili(1,2);Wei,   Ding(1,2,3);Song, Xiaoling(1);Jiang, Biao(1);Chen, Hongli(1). 2021-04-15.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY10.1016/j.ejmech.2021.113355

59. Construction of an IMiD-based azide   library as a kit for PROTAC research. Liu, Haixia(1,2,3);Sun, Renhong(1);Ren,   Chaowei(1,3,4);Qiu, Xing(5);Yang, Xiaobao(1);Jiang, Biao(1,5). 2021-01-07.   ORGANIC & BIOMOLECULAR CHEMISTRY10.1039/d0ob02120b

60. Cryo-EM Structure of an Extended   SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate   State in Cap Synthesis. Yan, Liming(1);Ge, Ji(2);Zheng, Litao(2);Zhang,   Ying(1);Gao, Yan(1,3);Wang, Tao(1);Huang, Yucen(1);Yang, Yunxiang(1);Gao, Shan(1);Li,   Mingyu(1);Liu, Zhenyu(1);Wang, Haofeng(3);Li, Yingjian(4);Chen, Yu(4);Guddat,   Luke W.(5);Wang, Quan(3);Rao, Zihe(1,2,3);Lou, Zhiyong(1). 2021-01-07.   CELL10.1016/j.cell.2020.11.016

61. CUTie2: The Attack of the Cyclic   Nucleotide Sensor Clones. Klein, Florencia(1,2);Sardi, Florencia(3);Machado,   Matias R.(1);Ortega, Claudia(4);Comini, Marcelo A.(3);Pantano, Sergio(1,5).   2021-03-11. FRONTIERS IN MOLECULAR BIOSCIENCES10.3389/fmolb.2021.629773

62. Discovery of novel BCR-ABL PROTACs based   on the cereblon E3 ligase design, synthesis, and biological evaluation. Liu   HX(刘海霞)(1,3,5);Ding XY(丁欣雨)(1,3,5);Liu LY(刘林义)(4);Mi QL(米强龙)(1,2);Zhao   QJ(赵全菊)(1);Shao YB(邵玉宝)(6);Ren CW(任超伟)(1,2);Chen JJ(陈金聚)(1);Kong Y(孔莹)(1);Chou   X(仇星)(7);Elvassore Nicola(1);Yang XB(杨小宝)(1);Yin QQ(阴倩倩)(1);Jiang B(姜标)(1,7).   2021-11-05. EUROPEAN JOURNAL OF MEDICINAL   CHEMISTRY10.1016/j.ejmech.2021.113645

63. Dissecting the role of glutamine in   seeding peptide aggregation. Barrera, Exequiel E.(1,3);Zonta,   Francesco(2);Pantano, Sergio(2,3). 2021. COMPUTATIONAL AND STRUCTURAL   BIOTECHNOLOGY JOURNAL10.1016/j.csbj.2021.02.014

64. DNA-Encoded Libraries: Hydrazide as a   Pluripotent Precursor for On-DNA Synthesis of Various Azole Derivatives. Ma,   Fei(1);Li, Jie(1);Zhang, Shuning(1);Gu, Yuang(1);Tan, Tingting(1);Chen,   Wanting(1);Wang, Shuyue(1);Ma, Peixiang(1);Xu, Hongtao(1);Yang, Guang(1);Lerner,   Richard A.(2). 2021-06-01. CHEMISTRY-A EUROPEAN JOURNAL10.1002/chem.202100850

65. Effective degradation of   EGFR(L858R+T790M) mutant proteins by CRBN-based PROTACs through both   proteosome and autophagy/lysosome degradation systems. Qu,   Xiaojuan(1,2,6);Liu, Haixia(1,3,6);Song, Xiaoling(1);Sun, Ning(1);Zhong,   Hui(1,4);Qiu, Xing(1,5);Yang, Xiaobao(1);Jiang, Biao(1,5). 2021-06-05.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY10.1016/j.ejmech.2021.113328

66. gem-Difluoromethylene Alkyne-Enabled   Diverse C-H Functionalization and Application to the on-DNA Synthesis of   Difluorinated Isocoumarins. Gao, Hui(3,4,5);Lin, Shuang(3,4,5);Zhang,   Shuning(1,2);Chen, Weijie(3,4,5);Liu, Xiamen(3,4,5);Yang, Guang(1);Richard A.   Lerner(6);Xu, Hongtao(1);Zhou, Zhi(3,4,5);Yi, Wei(3,4,5). 2021-01-25.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION10.1002/anie.202013052

67. Generation of a human induced   pluripotent stem cell line (SIAISi011-A) from a 61-year-old Chinese Han   healthy female donor. Zhang, Wenxin(1,2);Hua, Yishi(1);Di, Weihao(1,2);Guo,   Jinghui(1,2);Dai, Qiuting(1,2);Zhao, Jian(1,2);Zhang, Bei(3);Wang, Ying(1). 2021-03.   STEM CELL RESEARCH10.1016/j.scr.2021.102173

68. Generation of a human-derived induced   pluripotent stem cell line (SIAISi012-A) from an 82-year-old healthy Chinese   Han male. Guo, Jinghui(1,2);Fang, Fang(3);Dai, Qiuting(1,2);Zhang,   Wenxin(1,2);Di, Weihao(1,2);Hu, Jiaan(3);Zhao, Jian(1,2);Cao, Jiumei(3);Wang,   Ying(1). 2021-04. STEM CELL RESEARCH10.1016/j.scr.2021.102186

69. Generation of a SIAISi004-A hiPSC line   from PBMCs of a 74 year-old Alzheimer's disease woman by non-integrating   sendai virus mediated reprogramming. Zhang, Wenxin(1,2);Di, Weihao(1,2);Zhao,   Jian(1,2);Zhang, Bei(3);Wang, Ying(1). 2021-08. STEM CELL RESEARCH10.1016/j.scr.2021.102501

70. Generation of an induced pluripotent   stem cell line (SIAISi009-A) from a 60-year-old Chinese Han female with mild   cognitive impairment (MCI) having two copies of APOE4/4 allele. Guo,   Jinghui(1,2);Di, Weihao(1,2);Zhang, Wenxin(1,2);Dai, Qiuting(1,2);Zhao,   Jian(1,2);Deng, Yulei(3);Wang, Ying(1). 2021-03. STEM CELL   RESEARCH10.1016/j.scr.2021.102198

71. Generation of three iPSC cell lines   (SIAISi006-A, SIAISi007-A and SIAISi008-A) from a 66-year-old Alzheimer's   disease (AD) patient and her two unaffected children from Chinese Han   population. Zhang, Wenxin(1,2);Dai, Qiuting(1,2);Hua, Yishi(1);Di, Weihao(1,2);Guo,   Jinghui(1,2);Zhao, Jian(1,2);Deng, Yulei(3);Wang, Ying(1). 2021-03. STEM CELL   RESEARCH10.1016/j.scr.2021.102172

72. Harnessing the therapeutic potential of   antibodies targeting connexin hemichannels. Buratto, Damiano(1);Donati,   Viola(2);Zonta, Francesco(1);Mammano, Fabio(1,2,3). 2021-04-01. BIOCHIMICA ET   BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE10.1016/j.bbadis.2020.166047

73. High-throughput functional screening for   next-generation cancer immunotherapy using droplet-based microfluidics. Wang,   Yuan(1,2);Jin, Ruina(1,2);Shen, Bingqing(3);Li, Na(1,2);Zhou, He(3);Wang,   Wei(4);Zhao, Yingjie(5,6);Huang, Mengshi(3);Fang, Pan(3);Wang,   Shanshan(3);Mary, Pascaline(3);Wang, Ruikun(1,2);Ma, Peixiang(4);Li,   Ruonan(1,2);Tian, Yujie(1,2);Cao, Youjia(1,2);Li, Fubin(5,6);Schweizer,   Liang(3);Zhang, Hongkai(1,2,4). 2021-06. SCIENCE   ADVANCES10.1126/sciadv.abe3839

74. Inhibition of mitochondrial complex III   induces differentiation in acute myeloid leukemia. Zhang, Youping(1);Luo,   Ting(2);Ding, Xinyu(3);Chang, YungTing(4);Liu, Chuanxu(1);Zhang,   Yongqiang(2);Hao, Siguo(1);Yin, Qianqian(3);Jiang, Biao(3,5). 2021-04-02. BIOCHEMICAL   AND BIOPHYSICAL RESEARCH COMMUNICATIONS10.1016/j.bbrc.2021.02.027·

75. Mediator structure and conformation   change. Zhang, Heqiao(1,2);Chen, Dong-Hua(2);Mattoo, Rayees U.   H.(2);Bushnell, David A.(2);Wang, Yannan(1);Yuan, Chao(1);Wang, Lin(1);Wang,   Chunnian(1);Davis, Ralph E.(2);Nie, Yan(1);Kornberg, Roger D.(1,2).   2021-04-15. MOLECULAR CELL10.1016/j.molcel.2021.01.022

76. Molecular deconvolution of the   neutralizing antibodies induced by an inactivated SARS-CoV-2 virus vaccine.   Zhou, Xingdong(1,2,4);Wang, Hui(3);Ji, Qun(4);Du, Mingjuan(4);Liang,   Yuexia(1,2);Li, Huanhuan(1,2);Li, Fan(1,2);Shang, Hang(1,2);Zhu,   Xiujuan(3);Wang, Wei(4);Jiang, Lichun(4);Stepanov, Alexey V.(5);Ma,   Tianyu(1,2);Gong, Nanxin(1,2);Jia, Xiaodong(6);Gabibov, Alexander G.(5);Lou,   Zhiyong(7,8);Lu, Yinying(6);Guo, Yu(1,2);Zhang, Hongkai(1,2,4);Yang,   Xiaoming(3). 2021-10. PROTEIN & CELL10.1007/s13238-021-00840-z

77. Multiscale Co-reconstruction of Lung   Architectures and Inhalable Materials Spatial Distribution. Sun,   Xian(1,2,3);Zhang, Xiaochuan(4,5);Ren, Xiaohong(2);Sun, Hongyu(2);Wu,   Li(2);Wang, Caifen(2);Ye, Xiaohui(6,7);York, Peter(8);Gao, Zhaobing(5);Jiang,   Hualiang(4,5,6,7);Zhang, Jiwen(2,3,9);Yin, Xianzhen(1,5). 2021-02. ADVANCED   SCIENCE10.1002/advs.202003941

78. Neutralizing antibodies targeting   SARS-CoV-2 spike protein. Shi Xiaojie(1);Li Yu(1);Yan Lei(1);Yang   Guang(1);Qiang Min(1). 2021-01. STEM CELL RESEARCH10.1016/j.scr.2020.102125

79. Novel strategies to target EGFR proteins   for degradation and their applications in    non-small cell lung cancer. Xiaoling Song(1);Xiaojuan Qu(1,2);Siqi   Qu(1,2);Biao Jiang(1,3). 2021-12. CHINESE JOURNAL OF NATUREDOI: 10.3969/j.issn.0253-9608.2021.06.002

80. Palladium-catalyzed one-pot   phosphorylation of phenols mediated by sulfuryl fluoride dagger. Zhang,   Yiyuan(1,2,3,4);Chen, Wanting(1,2,3,4);Tan, Tingting(1,2,3,4);Gu,   Yuang(1,2,3,4);Zhang, Shuning(1,2,3,4);Li, Jie(1);Wang, Yan(1,2,3,4);Hou,   Wei(5,6);Yang, Guang(1);Ma, Peixiang(1);Xu, Hongtao(1). 2021-05-07. CHEMICAL   COMMUNICATIONS10.1039/d1cc00769f

81. Pomalidomide improves the function of   CD133-or HER2-specific CAR T cells. Wang, Zhixiong(1,2);Risu, Na(2);Fu,   Jiayu(2);Liu, Hui(3);Zhou, Guomin(3);Liu, Qian(3);Zou, Yan(4);Tang,   Jiaxing(4);Li, Long(4);Zhu, Xuekai(4). 2021. BIOCELL10.32604/biocell.2021.010261

82. Potent SARS-CoV-2 neutralizing   antibodies with protective efficacy against newly emerged mutational variants. Li Tingting(1,2,12);Han Xiaojian(1,2,12);Gu Chenjian(3,12);Guo   Hangtian(4,5,12);Zhang Huajun(6,12);Wang Yingming(1,2,12);Hu Chao(1,2);Wang   Kai(7);Liu Fengjiang(4);Luo Feiyang(1,2);Zhang Yanan(8,9);Hu Jie(7);Wang   Wang(1,2);Li Shenglong(1,2);Hao Yanan(1,2);Shen Meiying(10);Huang   Jingjing(1,2);Long Yingyi(1,2);Song Shuyi(1,2);Wu Ruixin(1,2);Mu   Song(1,2);Chen Qian(1,2);Gao Fengxia(1,2);Wang Jianwei(1,2);Long   Shunhua(1,2);Li Luo(1,2);Wu Yang(3);Gao Yan(4);Xu Wei(3);Cai Xia(3);Qu   Di(3);Zhang Zherui(8,9);Zhang Hongqing(8,9);Li Na(8,9);Gao Qingzhu(7);Zhang   Guiji(7);He Changlong(7);Wang Wei(11);Ji Xiaoyun(5,11);Tang Ni(7);Yuan   Zhenghong(3);Xie Youhua(3);Yang Haitao(4);Zhang Bo(8);Huang Ailong(7);Jin   Aishun(1,2). 2021-11-02. NATURE COMMUNICATIONS10.1038/s41467-021-26539-7

83. Rapid Assessment of Binding Affinity of   SARS-COV-2 Spike Protein to the Human Angiotensin-Converting Enzyme 2   Receptor and to Neutralizing Biomolecules Based on Computer Simulations.   Buratto, Damiano(1);Saxena, Abhishek(1);Ji, Qun(1);Yang, Guang(1);Pantano,   Sergio(1,2);Zonta, Francesco(1). 2021-11-11. FRONTIERS IN   IMMUNOLOGY10.3389/fimmu.2021.730099

84. Reshaping the Immune Microenvironment by   Oncolytic Herpes Simplex Virus in Murine Pancreatic Ductal Adenocarcinoma.   Zhang, Liming(1,2,3);Wang, Wei(4);Wang, Ruikun(1,2,3);Zhang,   Nianchao(3);Shang, Hang(1,2);Bi, Yang(1,2);Chen, Da(1,2);Zhang, Cuizhu(1,2,3);Li,   Long(5,6);Yin, Jie(5,6);Zhang, Hongkai(1,2,4);Cao, Youjia(1,2,3). 2021-02-03.   MOLECULAR THERAPY10.1016/j.ymthe.2020.10.027

85. SARS-CoV-2 infection and replication in   human gastric organoids. Giobbe, Giovanni Giuseppe(1);Bonfante,   Francesco(2);Jones, Brendan C.(1);Gagliano, Onelia(3);Luni,   Camilla(4);Zambaiti, Elisa(1,3,5);Perin, Silvia(1);Laterza,   Cecilia(3);Busslinger, Georg(6,7);Stuart, Hannah(3);Pagliari,   Matteo(2);Bortolami, Alessio(2);Mazzetto, Eva(2);Manfredi,   Anna(8,9);Colantuono, Chiara(8,9);Di Filippo, Lucio(8,9);Pellegata,   Alessandro Filippo(1);Panzarin, Valentina(2);Thapar, Nikhil(10);Li, Vivian   Sze Wing(11);Eaton, Simon(1);Cacchiarelli, Davide(8,12);Clevers,   Hans(6,7,13);Elvassore, Nicola(1,3,4,14);De Coppi, Paolo(1,15). 2021. NATURE   COMMUNICATIONS10.1038/s41467-021-26762-2

86. Selection of a picomolar antibody that   targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.   Xiaojie Shi(1);Yue Wan(1,2,3,4);Nan Wang(1,2,3,4);Jiangchao   Xiang(1,2,3,4);Tao Wang(1,2,3);Xiaofeng Yang(1);Ju Wang(1);Xuxue   Dong(1,2,3);Liang Dong(1,2);Lei Yan(1);Yu Li(1,2,3);Lili Liu(1);Shinchen   Hou(1);Zhenwei Zhong(1);Ian A. Wilson(6,7);Bei Yang(1);Guang Yang(1);Richard   A. Lerner(1,5). 2021-05-05. NATURE COMMUNICATIONS10.1038/s41467-021-22810-z

87. Single-cell RNA sequencing reveals   heterogeneous tumor and immune cell populations in early-stage lung   adenocarcinomas harboring EGFR mutations. He, Di(1,2);Wang, Di(2);Lu,   Ping(3);Yang, Nan(4);Xue, Zhigang(3);Zhu, Xianmin(1,2);Zhang, Peng(2);Fan,   Guoping(1,5). 2021-01-14. ONCOGENE10.1038/s41388-020-01528-0

88. Site-specific construction of   triptolide-based antibody-drug conjugates. Wei, Ding(1,2,3);Mao,   Yurong(2,3);Xu, Zili(2,3);Chen, Jiakang(2);Li, Jiusheng(1);Jiang,   Biao(2);Chen, Hongli(2). 2021-12-01. BIOORGANIC & MEDICINAL   CHEMISTRY10.1016/j.bmc.2021.116497

89. Structural basis for GTP-induced   dimerization and antiviral functioin of guanylate-binding proteins.   Cui,Wen(1,2,3);Braun,Elisabeth(4);Wang,Wei(3);Tang,Jinhong(1);Zheng,Yanyan(5);Slater,Benjamin(6);Li,Na(7);Chen,Cheng(1);Liu,Qingxiang(5);Wang,Bin(1);Li,Xiu(1);Duan,Yinkai(2);Xiao,Yunjie(1);Ti,Rujiao(1);Hotter,Dominik(4);Ji,Xiaoyun(3,8);Zhang,Lei(1);Cui,Jun(5);Xiong,Yong(6);Sauter,Daniel(4,9);Wang,Zefang(1,10);Kirchhoff,Frank(4);Yang,Haitao(1,2,10).   2021-04-13. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED   STATES OF AMERICA10.1073/pnas.2022269118

90. Structural basis for SARS-CoV-2   neutralizing antibodies with novel binding epitopes. Fu, Dan(1,2);Zhang,   Guangshun(1,2,3,4);Wang, Yuhui(1,2,4);Zhang, Zheng(1,2);Hu,   Hengrui(5,6);Shen, Shu(5,7,8);Wu, Jun(3);Li, Bo(1,2,4);Li, Xin(1,2,4,9);Fang,   Yaohui(7,8);Liu, Jia(5);Wang, Qiao(10);Zhou, Yunjiao(10);Wang, Wei(9);Li,   Yufeng(5);Lu, Zhonghua(3);Wang, Xiaoxiao(3);Nie, Cui(3);Tian,   Yujie(1,2,11);Chen, Da(1,2,4,11);Wang, Yuan(1,2,4,11);Zhou,   Xingdong(1,2,4,11);Wang, Qisheng(12);Yu, Feng(12);Zhang, Chen(1,2);Deng,   Changjing(3);Zhou, Liang(3);Guan, Guangkuo(3);Shao, Na(3);Lou,   Zhiyong(13,14);Deng, Fei(5,7,8);Zhang, Hongkai(1,2,9,11);Chen,   Xinwen(6,15);Wang, Manli(5);Liu, Louis(3);Rao, Zihe(1,2,4,9);Guo,   Yu(1,2,11,15). 2021. PLOS BIOLOGY10.1371/journal.pbio.3001209

91. Structural biology of SARS-CoV-2 and   implications for therapeutic development. Haitao Yang(1);Zihe Rao(1,2,3,4).   2021-11. NATURE REVIEWS MICROBIOLOGY10.1038/s41579-021-00630-8

92. Structure-based discovery of SIAIS001 as   an oral bioavailability ALK degrader constructed from Alectinib. Ren,   Chaowei(1,2,3);Sun, Ning(1);Kong, Ying(7);Qu, Xiaojuan(1,2,3);Liu,   Haixia(1,4);Zhong, Hui(1,6);Song, Xiaoling(1);Yang, Xiaobao(1);Jiang, Biao(1,5).   2021-05-05. EUROPEAN JOURNAL OF MEDICINAL   CHEMISTRY10.1016/j.ejmech.2021.113335

93. Sulfur [18F]Fluoride Exchange Click   Chemistry Enabled Ultrafast Late-Stage Radiosynthesis. Zheng, Qinheng(1);Xu,   Hongtao(2);Wang, Hua(1,3);Du, Wen-Ge Han(4);Wang, Nan(2);Xiong, Huan(2);Gu,   Yuang(2);Noodleman, Louis(4);Sharpless, K. Barry(1);Yang, Guang(2);Wu,   Peng(3). 2021-03-17. JOURNAL OF THE AMERICAN CHEMICAL   SOCIETY10.1021/jacs.0c09306

94. The main protease and RNA-dependent RNA   polymerase are two prime targets for SARS-CoV-2. Jin, Zhenming(1,2,3);Wang,   Haofeng(1,2);Duan, Yinkai(1);Yang, Haitao(1). 2021-01-29. BIOCHEMICAL AND   BIOPHYSICAL RESEARCH COMMUNICATIONS10.1016/j.bbrc.2020.10.091

95. Two novel strategies to overcome the   resistance to ALK tyrosine kinase inhibitor drugs: Macrocyclic inhibitors and   proteolysis‐targeting chimeras. Xiaoling Song(1);Hui Zhong(1,2);Xiaojuan   Qu(1);Linsong Yang(2);Biao Jiang(1,3). 2021-09. MEDCOMM10.1002/mco2.42

96. Beneficial effects exerted by   hydroxychloroquine in treating COVID-19 patients via protecting multiple   organs. Yu, Bo(1,2);Li, Chenze(1,2);Chen, Peng(1,2);Li, Jia(3);Jiang,   Hualiang(3,4,5);Wang, Dao-Wen(1,2). 2021-02. SCIENCE CHINA-LIFE   SCIENCES10.1007/s11427-020-1782-1

97. Conformational Changes in a Macrolide   Antibiotic Binding Protein From Mycobacterium smegmatis Upon ADP Binding.   Zhang, Qingqing(1,2);Liu, Xiang(1);Liu, Huijuan(1);Zhang, Bingjie(3);Yang,   Haitao(4,5);Mi, Kaixia(3);Guddat, Luke W.(6);Rao, Zihe(1,4,5,7,8). 2021-12-09.   FRONTIERS IN MICROBIOLOGY10.3389/fmicb.2021.780954

98. Coupling of N7-methyltransferase and 3   '-5 ' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for   capping and proofreading. Yan, Liming(1,2,3);Yang, Yunxiang(1,5);Li,   Mingyu(1);Zhang, Ying(1);Zheng, Litao(2,3,4);Ge, Ji(4);Huang, Yucen C.(1);Liu,   Zhenyu(1);Wang, Tao(1,2,3);Gao, Shan(1);Zhang, Ran(4);Huang, Yuanyun   Y.(6);Guddat, Luke W.(7);Gao, Yan(2,3);Rao, Zihe(1,2,3,4,8,9,10,11);Lou,   Zhiyong(1,11). 2021-06-24. CELL10.1016/j.cell.2021.05.033

99. CPA-seq reveals small ncRNAs with   methylated nucleosides and diverse termini. Wang, Heming(1,2,3);Huang,   Rong(1,2,3);Li, Ling(1);Zhu, Junjin(1,3);Li, Zhihong(4);Peng, Chao(4);Zhuang,   Xuran(1);Lin, Haifan(5,6);Shi, Shuo(7);Huang, Pengyu(1,3,8). 2021-04-19. CELL   DISCOVERY10.1038/s41421-021-00265-2

100. Cryo-EM structure determination captures   new chemical modification of protein. Jiang, Hualiang(1,2,3). 2021-10.   SCIENCE CHINA-LIFE SCIENCES10.1007/s11427-021-1886-8

101. Cryo-EM structure of mycobacterial   cytochrome bd reveals two oxygen access channels. Wang,   Weiwei(1,2,3,4,5);Gao, Yan(1,2);Tang, Yanting(3);Zhou, Xiaoting(1,2,4,5);Lai,   Yuezheng(3);Zhou, Shan(3);Zhang, Yuying(3);Yang, Xiuna(1,2);Liu,   Fengjiang(1,2,4,5);Guddat, Luke W.(6);Wang, Quan(1,2);Rao,   Zihe(1,2,3,7,8);Gong, Hongri(3). 2021-07-30. NATURE   COMMUNICATIONS10.1038/s41467-021-24924-w

102. Crystal structure of SARS-CoV-2 main   protease in complex with protease inhibitor PF-07321332. Zhao, Yao(1,2);Fang,   Chao(3);Zhang, Qi(1,2,4,5);Zhang, Ruxue(6);Zhao, Xiangbo(3);Duan,   Yinkai(1,2);Wang, Haofeng(1,2);Zhu, Yan(1,2);Feng, Lu(1,2);Zhao, Jinyi(1,2);Shao,   Maolin(1,2);Yang, Xiuna(1,2);Zhang, Leike(6);Peng, Chao(7);Yang,   Kailin(8);Ma, Dawei(3);Rao, Zihe(1,2,9,10,11);Yang, Haitao(1,2). 2021.   PROTEIN & CELL10.1007/s13238-021-00883-2

103. Design, synthesis, and biological   evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent   CDK2 inhibitors. Lin, Tingting(1,2,3,4,5);Li, Jiacheng(3,5);Liu,   Liping(3,5);Li, Yuanqing(3,5);Jiang, Hualiang(1,2,3,5);Chen,   Kaixian(1,2,3,5);Xu, Pan(3);Luo, Cheng(1,2,3,5);Zhou, Bing(4,5). 2021-04-05.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY10.1016/j.ejmech.2021.113281

104. Development of a Broadly Applicable   Cas12a-Linked Beam Unlocking Reaction for Sensitive and Specific Detection o   f Respiratory Pathogens Including SARS-CoV-2. Wang, Yu(1,2);Liu,   Donglan(3);Lin, Huihuang(4,5);Chen, Dingbin(3);Sun, Jing(3);Xie, Yusang(4,5);Wang,   Xinjie(1);Ma, Peixiang(1);Nie, Yan(1);Mei, Hong(1);Zhao, Baihui(6);Huang,   Xingxu(7);Jiang, Ge(1);Jiang, Xianxing(2);Qu, Jieming(4,5);Zhao,   Jincun(3);Liu, Jia(1,3,7). 2021-03-19. ACS CHEMICAL   BIOLOGY10.1021/acschembio.0c00840

105. Effects of Shuanghuanglian oral liquids   on patients with COVID-19: a randomized, open-label, parallel-controlled,   multicenter clinical trial. Ni, Li(1,2);Wen, Zheng(1,2);Hu, Xiaowen(3);Tang,   Wei(4);Wang, Haisheng(5);Zhou, Ling(1,2);Wu, Lujin(1,2);Wang, Hong(1,2);Xu,   Chang(1,2);Xu, Xizhen(1,2);Xiao, Zhichao(1,2);Li, Zongzhe(1,2);Li,   Chene(1,2);Liu, Yujian(1,2);Duan, Jialin(1,2);Chen, Chen(1,2);Li,   Dan(1,2);Zhang, Runhua(1,2);Li, Jinliang(6);Yi, Yongxiang(7,8);Huang,   Wei(1,2,9);Chen, Yanyan(10);Zhao, Jianping(11);Zuo, Jianping(4);Weng,   Jianping(3);Jiang, Hualiang(4,12,13);Wang, Dao Wen(1,2). 2021-10. FRONTIERS   OF MEDICINE10.1007/s11684-021-0853-6

106. Eliminating base-editor-induced   genome-wide and transcriptome-wide off-target mutations. Wang,   Lijie(1,2,3,4);Xue, Wei(5);Zhang, Hongxia(6,7);Gao, Runze(1,2,3,4);Qiu,   Houyuan(6,7);Wei, Jia(5);Zhou, Lina(1,2,3,4);Lei, Yun-Ni(1,5);Wu,   Xiaocheng(6,7);Li, Xiao(8);Liu, Chengfang(1,2,3,4);Wu, Jing(1,2);Chen,   Qiubing(6,7);Ma, Hanhui(1,2);Huang, Xingxu(1,2,3);Cai, Cheguo(8);Zhang,   Ying(9);Yang, Bei(1);Yin, Hao(6,7);Yang, Li(5);Chen, Jia(1,2,3). 2021-05.   NATURE CELL BIOLOGY10.1038/s41556-021-00671-4

107. High-throughput screening identifies   established drugs as SARS-CoV-2 PLpro inhibitors. Zhao, Yao(1,2);Du,   Xiaoyu(3,4);Duan, Yinkai(1,2);Pan, Xiaoyan(5);Sun, Yifang(6,7);You,   Tian(1,2);Han, Lin(6,7);Jin, Zhenming(1,2,3,4);Shang, Weijuan(5);Yu,   Jing(1,2);Guo, Hangtian(1,2);Liu, Qianying(6,7);Wu, Yan(5);Peng,   Chao(8);Wang, Jun(1,2);Zhu, Chenghao(1,2);Yang, Xiuna(1,2);Yang,   Kailin(9);Lei, Ying(1,2);Guddat, Luke W.(10);Xu, Wenqing(1,2,8);Xiao,   Gengfu(5);Sun, Lei(6,7);Zhang, Leike(5);Rao, Zihe(1,2,3,4);Yang, Haitao(1,2).   2021-11. PROTEIN & CELL10.1007/s13238-021-00836-9

108. Identification of Potential Binding   Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein. Li,   Bingqian(1,2,3);Wang, Lin(1,2);Ge, Huan(4);Zhang, Xianglei(1,2);Ren,   Penxuan(1,2);Guo, Yu(5,6);Chen, Wuyan(7);Li, Jie(7);Zhu, Wei(1,2);Chen, Wenzhang(1,2);Zhu,   Lili(4);Bai, Fang(1,2). 2021-07-22. FRONTIERS IN   CHEMISTRY10.3389/fchem.2021.659764

109. Identification of proteasome and caspase   inhibitors targeting SARS-CoV-2 M-pro. Wang, Zhengyuan(1);Zhao,   Yao(2,3);Wang, Qingxing(4);Xing, Yangfei;Feng, Lu(2,3);Kong, Juan(2,3);Peng,   Chao(5);Zhang, Leike(4);Yang, Haitao(2,3);Lu, Min(1). 2021-06-01. SIGNAL   TRANSDUCTION AND TARGETED THERAPY10.1038/s41392-021-00639-8

110. Inhibition mechanism of SARS-CoV-2 main   protease by ebselen and its derivatives. Amporndanai, Kangsa(1);Meng,   Xiaoli(2);Shang, Weijuan(3);Jin, Zhenmig(4,5);Zhao, Yao(4,5);Rao,   Zihe(4,5);Liu, Zhi-Jie(5,7);Yang, Haitao(4,5);Zhang, Leike(3);O'Neill, Paul   M.(6);Hasnain, S. Samar(1);Rogers, Michael(6). 2021-05-24. NATURE   COMMUNICATIONS10.1038/s41467-021-23313-7

111. Remdesivir overcomes the S861 roadblock   in SARS-CoV-2 polymerase elongation complex. Wu, Jiqin(1);Wang,   Haofeng(2);Liu, Qiaojie(1);Li, Rui(1,3);Gao, Yan(4);Fang, Xiang(1,3);Zhong,   Yao(1,3);Wang, Meihua(1,3);Wang, Quan(5,6);Rao, Zihe(4,5,6,7);Gong, Peng(1,8).   2021-10-26. CELL REPORTS10.1016/j.celrep.2021.109882

112. Structural and mechanistic insights into   the complexes formed by Wolbachia cytoplasmic incompatibility factors. Xiao,   Yunjie(1,2,3);Chen, Hongli(4);Wang, Haofeng(1,2,3,5);Zhang,   Mengwen(4,6);Chen, Xia(1);Berk, Jason M.(4);Zhang, Lilin(1);Wei, Yi(1);Li, Wenling(1);Cui,   Wen(1,5);Wang, Fenghua(1);Wang, Qianfan(1);Cui, Can(1);Li, Ting(1);Chen,   Cheng(1);Ye, Sheng(1);Zhang, Lei(1);Ji, Xiaoyun(5,7);Huang, Jinhai(1);Wang,   Wei(5);Wang, Zefang(1,8);Hochstrasser, Mark(4);Yang, Haitao(1,2,3,8).   2021-10-12. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED   STATES OF AMERICA10.1073/pnas.2107699118

113. Structure of Mycobacterium tuberculosis   cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates.   Zhou, Shan(1,2);Wang, Weiwei(3,4);Zhou, Xiaoting(3,4);Zhang, Yuying(2);Lai,   Yuezheng(2);Tang, Yanting(2);Xu, Jinxu(2);Li, Dongmei(1);Lin, Jianping(1);Yang,   Xiaolin(3,4);Ran, Ting(5);Chen, Hongming(5);Guddat, Luke W.(6);Wang,   Quan(3,4);Gao, Yan(3,4);Rao, Zihe(1,2,3,4,7,8);Gong, Hongri(2). 2021-11-25.   ELIFE10.7554/eLife.69418.sa2

114. Surfaceome CRISPR screen identifies   OLFML3 as a rhinovirus-inducible IFN antagonist (vol 22, 297, 2021). Mei,   Hong(1,2);Zha, Zhao(1,2);Wang, Wei(1,2);Xie, Yusang(3,4);Huang,   Yuege(1,2,5);Li, Wenping(1,2,5);Wei, Dong(6);Zhang, Xinxin(6);Qu,   Jieming(3,4);Liu, Jia(1,2,7,8,9,10). 2021-11-15. GENOME   BIOLOGY10.1186/s13059-021-02534-5

115. Structure-Based Design of Dual-Acting   Compounds Targeting Adenosine A(2A) Receptor and Histone Deacetylase as Novel   Tumor Immunotherapeutic Agents. Yan, Wenzhong(1);Ling, Lijun(2,3);Wu,   Yiran(1);Yang, Kexin(2,3);Liu, Ruiquan(1);Zhang, Jinfeng(1,3);Zhao, Simeng(1);Zhong,   Guisheng(1,3);Zhao, Suwen(1,3);Jiang, Hualiang(2,3,4);Xie,   Chengying(4,5);Cheng, Jianjun(1). 2021-11-25. JOURNAL OF MEDICINAL   CHEMISTRY10.1021/acs.jmedchem.1c01155

116. Surfaceome CRISPR screen identifies   OLFML3 as a rhinovirus-inducible IFN antagonist. Mei, Hong(1,2);Zha,   Zhao(1,2);Wang, Wei(1,2);Xie, Yusang(3,4);Huang, Yuege(1,2,5);Li,   Wenping(1,2,5);Wei, Dong(6);Zhang, Xinxin(6);Qu, Jieming(3,4);Liu,   Jia(1,2,7,8,9,10). 2021-10-22. GENOME BIOLOGY10.1186/s13059-021-02513-w

117. Discovery of a Brigatinib Degrader   SIAIS164018 with Destroying Metastasis-Related Oncoproteins and a Reshuffling   Kinome Profile. Ren, Chaowei(1,2,3);Sun, Ning(1,4,5);Liu, Haixia(1,3,6);Kong,   Ying(5,7);Sun, Renhong(1,4);Qiu, Xing(8);Chen, Jinju(7);Li, Yan(7);Zhang,   Jianshui(7);Zhou, Yuedong(7);Zhong, Hui(1,9);Yin, Qianqian(1);Song,   Xiaoling(1);Yang, Xiaobao(1);Jiang, Biao(1,6,8). 2021-07-08. JOURNAL OF   MEDICINAL CHEMISTRY10.1021/acs.jmedchem.1c00373

2020

1. gem-Difluoromethylene Alkyne-Enabled Diverse C-H Functionalization and Application to the on-DNA Synthesis of Difluorinated Isocoumarins. Gao, Hui(3,4,5);Lin, Shuang(3,4,5);Zhang, Shuning(1,2);Chen, Weijie(3,4,5);Liu, Xiamen(3,4,5);Yang, Guang(1);Richard A. Lerner(6);Xu, Hongtao(1);Zhou, Zhi(3,4,5);Yi, Wei(3,4,5). ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2020. DOI:. 10.1002/anie.202013052

2. Coarse-Grained Parameters for Divalent Cations within the SIRAH Force Field. Klein, Florencia(1);Caceres, Daniela(2,3);Carrasco, Monica A.(2);Carlos Tapia, Juan(2);Caballero, Julio(3);Alzate-Morales, Jans(3);Pantano, Sergio(1,4). JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2020. DOI:. 10.1021/acs.jcim.0c00160

3. Efficacy of early prone position for COVID-19 patients with severe hypoxia: a single-center prospective cohort study. Zang, Xuefeng(1);Wang, Qian(2);Zhou, Hua(3);Liu, Sanhong(4,5);Xue, Xinying(6,7). INTENSIVE CARE MEDICINE. 2020. DOI:. 10.1007/s00134-020-06182-4

4. Tripterygium glycoside fraction n2 ameliorates adriamycin-induced nephrotic syndrome in rats by suppressing apoptosis. Wang, Xiao-wan(1);Tian, Rui-min(2);Yang, Yi-qi(1);Wang, Kai(1);Li, En-nian(1);Han, Xiao-dong(1);Bao, Kun(2);Mao, Wei(1);Xu, Hong-tao(3);Liu, Bo(1,4);Xu, Peng(2). JOURNAL OF ETHNOPHARMACOLOGY. 2020. DOI:. 10.1016/j.jep.2020.112789

5. Selection of Small Molecules that Bind to and Activate the Insulin Receptor from a DNA-Encoded Library of Natural Products. Xie, Jia(1);Wang, Shuyue(2,3,4,5);Ma, Peixiang(2);Ma, Fei(1,2,5);Li, Jie(2,3,4);Wang, Wei(2);Lu, Fengping(2);Xiong, Huan(2);Gu, Yuang(2,3,4,5);Zhang, Shuning(2,3,4,5);Xu, Hongtao(2);Yang, Guang(2);Lerner, Richard A.(1). ISCIENCE. 2020. DOI:. 10.1016/j.isci.2020.101197

6. Intravital three-dimensional bioprinting. Urciuolo, Anna(1,2,3);Poli, Ilaria(4);Brandolino, Luca(1,2);Raffa, Paolo(2,3);Scattolini, Valentina(2,3);Laterza, Cecilia(1,2);Giobbe, Giovanni G.(5);Zambaiti, Elisa(3);Selmin, Giulia(5);Magnussen, Michael(5);Brigo, Laura(2);De Coppi, Paolo(5,6);Salmaso, Stefano(7);Giomo, Monica(1);Elvassore, Nicola(1,2,5,8). NATURE BIOMEDICAL ENGINEERING. 2020. DOI:. 10.1038/s41551-020-0568-z

7. Identification of exosomal miRNAs as diagnostic biomarkers for cholangiocarcinoma and gallbladder carcinoma. Xue, Xin-ying(1,2,3);Liu, Yu-xia(4);Wang, Chen(5);Gu, Xin-jin(6);Xue, Zhi-qiang(7);Zang, Xue-lei(8);Ma, Xi-dong(3);Deng, Hui(1);Liu, Rong(6);Pan, Lei(1);Liu, San-hong(5). SIGNAL TRANSDUCTION AND TARGETED THERAPY. 2020. DOI:. 10.1038/s41392-020-0162-6

8. Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity. Zhang, Xiaotian(1,4);Jeong, Mira(1,2);Huang, Xingfan(3,7,8,17);Wang, Xue Qing(4);Wang, Xinyu(5);Zhou, Wanding(4);Shamim, Muhammad S.(3,6,7,8);Gore, Haley(4);Himadewi, Pamela(4);Liu, Yushuai(4);Bochkov, Ivan D.(3,9);Reyes, Jaime(1,2,9);Doty, Madison(10);Huang, Yung-Hsin(1,2,11);Jung, Haiyoung(1,2,12);Heikamp, Emily(1,2,13);Aiden, Aviva Presser(3,11,13);Li, Wei(14,15);Su, Jianzhong(5);Aiden, Erez Lieberman(3,7,8,9,16);Goodell, Margaret A.(1,2,9,13,15). MOLECULAR CELL. 2020. DOI:. 10.1016/j.molcel.2020.04.018

9. Engineering a 3D in vitro model of human skeletal muscle at the single fiber scale. Urciuolo, Anna(1,2,3);Serena, Elena(1,2);Ghua, Rusha(4);Zatti, Susi(1,2);Giomo, Monica(1,2);Mattei, Nicolo(1,2);Vetralla, Massimo(1,2);Selmin, Giulia(1);Luni, Camilla(5);Vitulo, Nicola(6);Valle, Giorgio(4);Vitiello, Libero(4,7);Elvassore, Nicola(1,2,5,8). PLOS ONE. 2020. DOI:. 10.1371/journal.pone.0232081

10. Exosomal piRNA profiling revealed unique circulating piRNA signatures of cholangiocarcinoma and gallbladder carcinoma. Gu, Xinjin(1);Wan, Chen(2);Deng, Hui(3);Qing, Chong(3);Liu, Rong(1);Liu, Sanhong(2);Xue, Xinying(3). ACTA BIOCHIMICA ET BIOPHYSICA SINICA. 2020. DOI:. 10.1093/abbs/gmaa028

11. Establishment of SIAISi002-A, an induced pluripotent stem cell (iPSC) line from 39-year old healthy female donor with a family history of Alzheimer's disease (AD) and two copies of APOE4 gene. Yan, Yi(1,2);Qiu, Yinghui(1,2);Zhao, Aonan(1,2);Zhao, Jian(3,4);Wang, Ying(3);Deng, Yulei(1,2). STEM CELL RESEARCH. 2020. DOI:. 10.1016/j.scr.2020.101792

12. Bcl-3 promotes Wnt signaling by maintaining the acetylation of beta-catenin at lysine 49 in colorectal cancer. Chen, Xi(1);Wang, Chen(1,2);Jiang, Yuhang(1,3);Wang, Qi(1);Tao, Yu(1,3);Zhang, Haohao(1,3);Zhao, Yongxu(1);Hu, Yiming(1,3);Li, Cuifeng(1,3);Ye, Deji(1);Liu, Dandan(1);Jiang, Wenxia(1);Chin, Eugene Y.(1);Chen, Sheng(4);Liu, Yongzhong(5);Wang, Mingliang(6);Liu, Sanhong(1,2);Zhang, Xiaoren(1,3). SIGNAL TRANSDUCTION AND TARGETED THERAPY. 2020. DOI:. 10.1038/s41392-020-0138-6

13. Celastrol: Progresses in structure-modifications, structure-activity relationships, pharmacology and toxicology. Hou, Wei(1,2);Liu, Bo(3,4);Xu, Hongtao(5). EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2020. DOI:. 10.1016/j.ejmech.2020.112081

14. Exosomal miRNA profiling before and after surgery revealed potential diagnostic and prognostic markers for lung adenocarcinoma. Xue, Xinying(1,2);Wang, Chen(3);Xue, Zhiqiang(4);Wen, Jiaxin(4);Han, Jun(5);Ma, Xidong(6);Zang, Xuelei(7);Deng, Hui(2);Guo, Rui(2);Asuquo, Idorenyin Polycarp(8);Qin, Chong(2);Wang, Haijiao(2);Gao, Quansheng(9);Liu, Sanhong(3);Wang, Jianxin(1). ACTA BIOCHIMICA ET BIOPHYSICA SINICA. 2020. DOI:. 10.1093/abbs/gmz164

15. Establishment of SIAISi001-A, an induced pluripotent stem cell (iPSC) line from 66-year old mild cognitive impairment (MCI) with two copies of APOE4 gene. Yan, Yi(1,2);Qiu, Yinghui(1,2);Zhao, Aonan(1,2);Zhao, Jian(3);Wang, Ying(3);Deng, Yulei(1,2). STEM CELL RESEARCH. 2020. DOI:. 10.1016/j.scr.2020.101702

16. ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin(STAG1) from WAPL. Wutz, Gordana(1);Ladurner, Rene(1,15);St Hilaire, Brian Glenn(2,3,4);Stocsits, Roman R.(1);Nagasaka, Kota(1);Pignard, Benoit(1);Sanborn, Adrian(2,5);Tang, Wen(1);Varnai, Csilla(6,7);Ivanov, Miroslav P.(1,16);Schoenfelder, Stefan(6,17);van der Lelij, Petra(1);Huang, Xingfan(2,8,9,10);Duernberger, Gerhard(11,18);Roitinger, Elisabeth(11);Mechtler, Karl(1,11);Davidson, Iain Finley(1);Fraser, Peter(6,12);Lieberman-Aiden, Erez(2,3,4,8,13,14);Peters, Jan-Michael(1). ELIFE. 2020. DOI:. 10.7554/eLife.52091

17. Post-Translational Modifications at the Coarse-Grained Level with the SIRAH Force Field. Garay, Pablo G.(1);Barrera, Exequiel E.(1);Pantano, Sergio(1,2). JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2020. DOI:. 10.1021/acs.jcim.9b00900

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19. Architecture of a SARS-CoV-2 mini replication and transcription complex. Yan, Liming(1);Zhang, Ying(2);Ge, Ji(2);Zheng, Litao(2);Gao, Yan(1,3,4);Wang, Tao(1);Jia, Zhihui(5);Wang, Haofeng(3,4);Huang, Yucen(1);Li, Mingyu(1);Wang, Quan(3,4);Rao, Zihe(1,2,3,4);Lou, Zhiyong(1). NATURE COMMUNICATIONS. 2020. DOI:. 10.1038/s41467-020-19770-1

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2019

1. Zhang B#, Li J#*, Yang X, Wu L, Zhang J, Yang Y, Zhao Y, Zhang L, Yang X, Yang X, Cheng X, Liu Z, Jiang B, Jiang H, Guddat LW, Yang H*, Rao Z*. Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell. 2019 Jan 24. ISSN: 0092-8674;

2. 201. Structural analysis of fungal CENP-H/I/K homologs reveals a conserved assembly mechanism underlying proper chromosome alignment. Nucleic Acids Research. 2019 Jan 10. ISSN:0305-1048;    

3. Lu, Xiaoyun#;  Liu, Yuwan#;  Yang, Yiqun#;  Wang, Shanshan#;  Wang, Qian;  Wang, Xiya;  Yan, Zhihui;  Cheng, Jian;  Liu, Cui;  Yang, Xue;  Luo, Hao;  Yang, Sheng;  Gou, Junran;  Ye, Luzhen;  Lu, Lina;  Zhang, Zhidan;  Guo, Yu;  Nie, Yan;  Lin, Jianping;  Li, Sheng;  Tian, Chaoguang;  Cai, Tao;  Zhuo, Bingzhao;  Ma, Hongwu;  Wang, Wen;  Ma, Yanhe;  Liu, Yongjun*;  Li, Yin*;  Jiang, Huifeng*. Constructing a synthetic pathway for acetylcoenzyme A from one-carbon through enzyme design. Nature Communications. 2019 Mar 26. ISSN:2041-1723;  

4. Wang Xinyu#; Pu Jiahua#; Liu Yi; Ba Fang; Cui Mengkui; Li Ke; Xie Yu; Nie Yan; Mi Qixi; Li Tao; Liu Lingli; Zhu Manzhou; Zhong Chao*. Immobilization of functional nano-objects in living engineered bacterial biofilms for catalytic applications. National Science Review. 2019 Jul 30. ISSN:2053-714X;    

5. Wang, Yannan#;  Zhang, Fan;  Nie, Yan*;  Shang, Guijun*;  Zhang, Heqiao*. Structural analysis of Shigella flexneri bi-functional enzyme HisIE in histidine biosynthesis. Biochemical and Biophysical Research Communications. 2019 Aug 20. ISSN:0006-291X;    

6. El Khattabi, Laila#;  Zhao, Haiyan#;  Kalchschmidt, Jens#;  Young, Natalie#;  Jung, Seolkyoung;  Van Blerkom, Peter;  Kieffer-Kwon, Philippe;  Kieffer-Kwon, Kyong-Rim;  Park, Solji;  Wang, Xiang;  Krebs, Jordan;  Tripathi, Subhash;  Sakabe, Noboru;  Sobreira, Debora R.;  Huang, Su-Chen;  Rao, Suhas S. P.;  Pruett, Nathanael;  Chauss, Daniel;  Sadler, Erica;  Lopez, Andrea;  Nobrega, Marcelo A.;  Aiden, Erez Lieberman;  Asturias, Francisco J.*;  Casellas, Rafael*. A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers. Cell. 2019 Aug 22. ISSN:0092-8674;   

7. Zhang, Yu#; Zhang, Xuefei#; Ba, Zhaoqing; Liang, Zhuoyi; Dring, Edward W.; Hu, Hongli; Lou, Jiangman; Kyritsis, Nia; Zurita, Jeffrey; Shamim, Muhammad S.; Aiden, Aviva Presser; Aiden, Erez Lieberman; Alt, Frederick W*. The fundamental role of chromatin loop extrusion in physiological V(D)J recombination. Nature. 2019 Sep 11. ISSN:0028-0836;  

8. Qiu, Xing#; Sun, Ning#; Kong, Ying; Li, Yan; Yang, Xiaobao*; Jiang, Biao* . Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Organic Letters. 2019 May 8. ISSN:1523-7060;  

9. Zhao, Quanju1#; Ren, Chaowei#; Liu, Linyi#; Chen, Jinju; Shao, Yubao; Sun, Ning; Sun, Renhong; Kong, Ying; Ding, Xinyu; Zhang, Xianfang; Xu, Youwei; Yang, Bei; Yin, Qianqian*; Yang, Xiaobao*; Jiang, Biao*. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. Journal of Medicinal Chemistry. 2019 Oct 2. ISSN:0022-2623;  

10. Rong Huang, Zhihong Li, Jianghui Yu, Hongli Chen,* and Biao Jiang*. H2O‑Regulated Chemoselectivity in Oxa-Versus Aza-Michael Reactions. Organic Letters. 2019 May 16. ISSN:1523-7060 ;  

11. Rong Huang,# Wei Zhu,# Yue Wu,# Jiakang Chen, Jianghui Yu, Biao Jiang,* Hongli Chen * and Wenzhang Chen*. A novel mass spectrometry-cleavable, phosphatebased enrichable and multi-targeting protein cross-linker. Chemical Science. 2019 May 23. ISSN:1452-3981;  

12. Zhenzhen Yang#, Eric K. Wafula, Gunjune Kim, Saima Shahid, Joel R. McNeal, Paula E. Ralph, Prakash R. Timilsena, Wen-bin Yu, Elizabeth A. Kelly, Huiting Zhang, Thomas Nate Person, Naomi S. Altman, Michael J. Axtell, James H. Westwood & Claude W. dePamphilis* . Convergent horizontal gene transfer and cross-talk of mobile nucleic acids in parasitic plants. Nature plants. 2019 Jul 22. ISSN:2055026X;  

13. Gagliano O#, Luni C#, Qin W, Bertin E, Torchio E, Galvanin S, Urciuolo A, Elvassore N*.. Microfluidic reprogramming to pluripotency of human somatic cells. Nat Prot. 2019. ISSN:1745-2473;  

14. Martewicz S#, Luni C#, Serena E, Pavan P, Chen VH-S, Rampazzo A, Elvassore N*.. Transcriptomic characterization of a human in vitro model of arrhythmogenic cardiomyopathy under topological and mechanical stimuli. Ann Biomed Eng. 2019. ISSN:0090-6964 (Print) 1573-9686 (Online);  

15. Giobbe GG#, Crowley C#, Luni C#, Campinoti S, Khedr M, Kretzschmar K, De Santis MM, Zambaiti E, Hu Q, Michielin F, Meran L, Urbani L, Manfredi A, van Son G, Eaton S, Cacchiarelli D, Li VSW, Clevers H, Bonfanti P, Elvassore N*, De Coppi P*. Extracellular matrix hydrogel derived from decellularized tissues enables endoderm organoid culture. Nat Commun. 2019 (in press). ISSN:2041-1723;  

16. Wang Chen#, Yang Zhenzhen, Guo Fanghao, Shi Shuo, Han Xiaoshuai, Zeng An, Lin Haifan*, Jing Qing*. Heat shock protein DNAJA1 stabilizes PIWI proteins to support regeneration and homeostasis of planarian Schmidtea mediterranea. J Biol Chem. 2019 Jun 21. ISSN:0021-9258;  

17. Xinying Xue#, Chen Wang#, Zhiqiang Xue#, Jiaxin Wen,Jun Han, Xidong Ma, Xuelei Zang, Hui Deng, Rui Guo, Idorenyin Polycarp Asuquo, Chong Qin, Haijiao Wang, Quansheng Gao*, Sanhong Liu*, Jianxin Wang*. Exosomal miRNA profiling before and after surgery revealed potential diagnostic and prognostic markers for lung adenocarcinoma. Acta Biochimica et Biophysica Sinica. 2019 Nov 15. ISSN:1672-9145;  

18. Tonon F#, Giobbe GG#, Zambon A, Luni C, Gagliano O, Floreani A, Grassi G, Elvassore N*. In vitro metabolic zonation through oxygen gradient on a chip. Sci Rep. 2019. ISSN:2045-2322;  

19. Zoso A#, Zambon A#, Gagliano O, Giulitti S, Prevedello L, Fadini GP, Luni C, Elvassore N*.. Cross-talk of healthy and impaired human tissues for dissection of disease pathogenesis. Biotechnol Progr. 2019. ISSN:8756-7938 (print) 1520-6033 (Online);  

20. Beninatto R#*, Barbera C, De Lucchi O, Borsato G, Serena E, Guarise C, Pavan M, Luni C, Martewicz S, Galesso D, Elvassore N*. Photocrosslinked hydrogels from coumarin derivatives of hyaluronic acid for tissue engineering applications. Mater Sci Eng C Mater Biol Appl. 2019. ISSN:0928-4931;  

21. Wang M#, Guo X#, Yang X, Zhang B, Ren J, Liu A, Ran Y, Yan B, Chen F, Guddat LW, Hu J*, Li J* and Rao Z. Mycobacterial dynamin-like protein IniA mediates membrane fission. . Nat Commun. 2019 Aug 29. ISSN:2041-1723;

22. Wang S#, Zhou K, Yang X, Zhang B, Zhao Y, Xiao Y, Yang X, Yang H, Guddat LW, Li J, Rao Z. LW, Li J*, Rao Z*. Structural insights into substrate recognition by the type VII secretion system..Protein & Cell. . 2019 Nov 23. ISSN:1674-8018;  

23. Wang N#, Zhao D#, Wang J#, Zhang Y#, Wang M, Gao Y, Li F, Wang J, Bu Z*, Rao Z*, Wang X*. Architecture of African swine fever virus and implications for viral assembly. Science. 2019 Nov 1. ISSN:0033-3131;  

24. Xia S#, Yan L#, Xu W, Agrawal AS, Algaissi A, Tseng CK, Wang Q, Du L, Tan W, Wilson IA*, Jiang S*, Yang B*, Lu L*. A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Science Advances. 2019 Apr 10. ISSN:2375-2548;  

25. Pang X#, Tong Y, Xue W, Yang Y-F, Chen X, Liu J*, Chen D*. Expression and characterization of recombinant human lactoferrin in edible alga Chlamydomonas reinhardtii. Bioscience, Biotechnology, and Biochemistry. 2019 Jan 23. ISSN:0916-8451;  

26. Li B#, Zhou X-H# Yang P-Y, Zhu L, Zhong Y, Cai Z, Jiang B, Cai X, Liu J*, Jiang X*. Photoactivatable Fluorogenic Labeling via Turn-On Click-Like Nitroso-Diene Bioorthogonal Reaction. Advanced Science. 2019 May 2. ISSN:2198-3844;  

27. Pang X#, Tong Y, Li F, Wei X, Chen X*, Liu J*, Chen D*. Expression and characterization of human lactoferrin with tandem zinc finger protein in Chlamydomonas reinhardtii. Algal Research. 2019 Nov. ISSN:2211-9264;  

28. Li L#, Ngo HTT, Hwang E, Wei X, Liu Y, Liu J*, Yi T-H*. Conditioned medium from human adipose-derived mesenchymal stem cell culture prevents UVB-induced skin aging in human keratinocytes and dermal fibroblasts. International Journal of Molecular Sciences. In press. ISSN:1422-0067;  

29. Bian Hu#, Yan Zou, Linlin Zhang, Jiaxing Tang, Gabriele Niedermann, Elke Firat, Xingxu Huang*, and Xuekai Zhu*. Nucleofection with Plasmid DNA for CRISPR/Cas9-Mediated Inactivation of Programmed Cell Death Protein 1 in CD133-Specific CAR T Cells. Human Gene Therapy. 2019 Apr 10. ISSN:1557-7422;   

30. Qinan Yin#, Jiaxing Tang, Xuekai Zhu*. Next-generation sequencing technologies accelerate advances in T-cell therapy for cancer. Briefings in Functional Genomics. 2019 Mar 22. ISSN:2041-2657;  

31. Shi X#, Xiao Z#, Zonta F, Wang W, Wan Y, Li Y, Wang N, Kuang Y, Du M, Dong J, Wang J, Yang G*. Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte. Stem Cells. 2019 Feb 28. ISSN:1066-5099;  

32. Ma P#, Xu H#, Li J#, Lu F, Ma F, Wang S, Xiong H, Wang W, Buratto D, Zonta F, Wang N, Liu K, Hua T, Zhi-jie Liu, Yang G*, Lerner RA*. Functionality independent DNA encoding of complex natural products. Angew Chem Int Ed Engl. 2019 May 22. ISSN:1433-7851;  

33. Liu Y, Zhang J, Wang R, Wu Y, Wang W, Xin X, Du M, Cao Y, Zhang H*. Identification of novel Kv1.3 targeting venom peptides by a single round of autocrine-based selection. Biochem Biophys Res Commun. 2019 Jan 14. ISSN:0006-291X;  

34. Yang YQ, Liang J, Han XD, Tian RM, Liu XS, Mao W, Xu HT*, Liu B*, Xu P*. Dual-function of triptriolide in podocytes injury: inhibiting of apoptosis and restoring of survival. Biomed Pharmacother. 2019 Jan 14. ISSN:0753-3322;  

35. Lu Y, Yan JS, Xia L, Qin K, Yin QQ, Xu HT, Gao MQ, Qu XN, Sun YT, Chen GQ. 2-Bromopalmitate targets retinoic acid receptor alpha and overcomes all-trans retinoic acid resistance of acute promyelocytic leukemia. Haematologica. 2019 Aug 3. ISSN:0390-6078;  

36. Ziraldo G, Buratto D, Kuang Y, Xu L, Carrer A, Nardin C, Chiani F, Salvatore AM, Paludetti G, Lerner RA, Yang G, Zonta F, Mammano F*. A human-derived monoclonal antibody targeting extracellular connexin domain selectively modulates hemichannel function. Frontiers in Physiology. 2019 Jun 11. ISSN:1664-042X;  

37. H. Xu*, B. Liu*. Triptolide-targeted delivery methods. Eur. J. Med. Chem. 2019 Feb 15. ISSN:0223-5234;  

38. W. Hou, G. Zhang, Z. Luo, L. Su*, H. Xu*. Click chemistry‐based synthesis and cytotoxic activity evaluation of 4α‐triazole acetate podophyllotoxin derivatives. Chem. Biol. Drug Des. 2019 Nov 28. ISSN:1747-0277;  

39. Yang Z, Wan Y, Tao P, Qiang M, Dong X, Lin CW, Yang G, Zheng T*, Lerner RA*. A cell-cell interaction format for selection of high-affinity antibodies to membrane proteins. Proc Natl Acad Sci U S A. 2019 Jul 23. ISSN:0027-8424;  

40. Xu H#.Ma F#.Wang N.Hou W.Xiong H.Lu F, Li J.Wang S.Ma P.Yang G*.Lerner RA*.. DNA-Encoded Libraries: Aryl Fluorosulfonates as Versatile Electrophiles Enabling Facile On-DNA Suzuki, Sonogashira, and Buchwald Reactions. Advance Science. 2019 Sep 30. ISSN:2198-3844;  

41. Zhang S, Xiong H, Lu F, Ma F, Gu Y, Ma P*, Xu H*, Yang G*. Synthesis of N-Acyl Sulfamates from Fluorosulfonates and Potassium Trimethylsilyloxyl Imidates. J Org Chem. 2019 Nov 12. ISSN:0022-3263;  

42. W. Hou, B. Liu*, H. Xu*. Triptolide: medicinal chemistry, chemical biology and clinical progress. Eur. J. Med. Chem. 2019 May 13. ISSN:0223-5234;  

43. W. Hou, H. Xiong, R. Bai, Z. Xiao, L. Su, B.H. Ruan*, H. Xu*. Synthesis of Indazolo[2,1-a]Cinnolines via Rhodium (III)-Catalyzed C–H activation/annulation under mild conditions. Tetrahedron. 2019 Jun 24. ISSN:0040-4020;  

44. X. Wang, R. Tian, Y. Yang, Z.-Y. Lu, X. Han, X. Liu, W. Mao, P. Xu*, H. Xu*, B. Liu*. Triptriolide antagonizes triptolide-induced nephrocyte apoptosis via inhibiting oxidative stress in vitro and in vivo. Biomed Pharmacother. 2019 Jul 15. ISSN:0753-3322;  

45. Nielsen BS#, Zonta F, T Farkas, T Litman, MS Nielsen, N MacAulay*. Structural determinants underlying permeant discrimination of the Cx43 hemichannel. Journal of Biological Chemistry. 2019 Nov 08. ISSN:1083-351X;  

46. Yang Zhang#, Xiaodan Sun#, Yangyang Qian, Hongfei Yi, Ke Song, Huanhu Zhu, Francesco Zonta, Weizhong Chen, Quanjiang Ji, Shane Miersch, Sachdev S Sidhu*, Donghui Wu*. A potent anti-SpuE antibody allosterically inhibits type III secretion system and attenuates virulence of Pseudomonas aeruginosa, Journal of molecular biology. 2019 Nov 02. ISSN:0022-2836;  

47. Gaia Ziraldo#, Damiano Buratto#, Yuanyuan Kuang, Liang Xu, Andrea Carrer, Chiara Nardin, Francesco Chiani, Anna Maria Salvatore, Gaetano Paludetti, Richard A Lerner, Guang Yang*, Francesco Zonta*, Fabio Mammano*. A human-derived monoclonal antibody targeting extracellular connexin domain selectively modulates hemichannel function. Frontiers in physiology. 2019 Jun 11. ISSN:1664-042X

48. Nielsen BS#, Zonta F, T Farkas, T Litman, MS Nielsen, N MacAulay*. Structural determinants underlying permeant discrimination of the Cx43 hemichannel. Journal of Biological Chemistry, 2019, 294 (45), 16789-16803

49. Yang Zhang#, Xiaodan Sun#, Yangyang Qian, Hongfei Yi, Ke Song, Huanhu Zhu, Francesco Zonta, Weizhong Chen, Quanjiang Ji, Shane Miersch, Sachdev S Sidhu*, Donghui Wu*. A potent anti-SpuE antibody allosterically inhibits type III secretion system and attenuates virulence of Pseudomonas aeruginosa. Journal of molecular biology, Volume 431, Issue 24, 6 December 2019, Pages 4882-4896