2020

1. Thierry Lonhienne#*, Yu Shang Low#, Mario D. Garcia, Tristan Croll, Yan Gao, Quan Wang, Lou Brillault, Craig M. Williams, James A. Fraser, Ross P. McGeary, Nicholas.P.West, Michael J. Landsberg, Zihe Rao, Gerhard Schnek and Luke W. Guddat*. Structures of fungal and plant acetohydroxyacid synthases. Nature (2020). https://doi.org/10.1038/s41586-020-2514-3

2. Xu, Hongtao#, Gu, Yuang#, Zhang, Shuning, Xiong, Huan, Ma, Fei, Lu, Fengping; Ji, Qun, Liu, Lili, Ma, Peixiang, Hou, Wei*, Yang, Guang*, Lerner, Richard A.* (2020).A Chemistry for Incorporation of Selenium into DNA-Encoded Libraries. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.

3. Wang Q#*, Wu J#, Wang H#, Gao Y#, Liu Q#, Mu A, Ji W, Yan L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F, Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B, Guddat LW, Gong P*, Rao Z* (2020). Structural basis for RNA replication by the SARS-CoV-2 polymerase. Cell. doi: https://doi.org/10.1016/j.cell.2020.05.034.
   

4. Zhang L#, Zhao Y#, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q*, Li J*, Besra GS*, Rao Z* (2020). Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science. DOI: 10.1126/science.aba9102       

5. Dai W#, Zhang B#, Jiang X#, , Su H#, Li J, Zhao Y, Xie X, Jin Z, Liu F, Li C, Li Y, Bai F, Wang H, Cheng X, Cen X, Hu S, Yang X, Wang J, Liu X, Xiao G, Jiang H, Rao Z, Zhang LK*, Xu Y*, Yang H*, Liu H* (2020). Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. Science. DOI: 10.1126/science.abb4489

6. Zhenming Jin#, Yao Zhao#, Yuan Sun#, Bing Zhang, Haofeng Wang, Yan Wu, Yan Zhu, Chen Zhu, Tianyu Hu, Xiaoyu Du, Yinkai Duan, Jing Yu, Xiaobao Yang, Xiuna Yang, Kailin Yang, Xiang Liu, Luke W. Guddat, Gengfu Xiao, Leike Zhang*, Haitao Yang* & Zihe Rao. Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur. Nat Struct Mol Biol (2020). https://doi.org/10.1038/s41594-020-0440-6

7. Yan Gao#, Liming Yan#, Yucen Huang#, Fengjiang Liu#, Yao Zhao, Lin Cao, Tao Wang, Qianqian Sun, Zhenhua Ming, Lianqi Zhang, Ji Ge, Litao Zheng, Ying Zhang, Haofeng Wang, Yan Zhu, Chen Zhu, Tianyu Hu, Tian Hua, Bing Zhang, Xiuna Yang, Jun Li, Haitao Yang, Zhijie Liu, Wenqing Xu, Luke W. Guddat, Quan Wang*, Zhiyong Lou*, Zihe Rao*. Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science  10 Apr 2020:DOI: 10.1126/science.abb7498

8. Zhenming Jin#, Xiaoyu Du#, Yechun Xu#, Yongqiang Deng#, Meiqin Liu#, Yao Zhao, Bing Zhang, Xiaofeng Li, Leike Zhang, Chao Peng, Yinkai Duan, Jing Yu, Lin Wang, Kailin Yang, Fengjiang Liu, Rendi Jiang, Xinglou Yang, Tian You, Xiaoce Liu, Xiuna Yang, Fang Bai, Hong Liu, Xiang Liu, Luke W. Guddat, Wenqing Xu, Gengfu Xiao, Chengfeng Qin, Zhengli Shi, Hualiang Jiang*, Zihe Rao*, Haitao Yang*. Structure of Mpro from COVID-19 virus and discovery of its inhibitors. Nature (2020) Published: 09 April 2020

9. Uyhazi, Katherine E.#, Yang, Yiying#, Liu, Na, Qi, Hongying, Huang, Xiao, Mak, Winifred, Weatherbee, Scott D., de Prisco, Nicola, Gennarino, Vincenzo A., Song, Xiaoling, Lin, Haifan *(2020). Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,117(14),7851-7862.

10. Yan-ru Cui#, Shao-jie Wang#, Jun Chen, Jie Li, Wenzhang Chen, Shuyue Wang, Bing Meng, Wei Zhu, Zhuhong Zhang, Bei Yang, Biao Jiang, Guang Yang , Peixiang Ma*, Jia Liu*. Allosteric inhibition of CRISPR-Cas9 by bacteriophage-derived peptides. Genome Biology volume 21, Article number: 51 (2020)

11. Liu S, Miersch S, Li P, Bai B, Liu C, Qin W, Su J, Huang H, Pan J, Sidhu SS, Wu D.（2020）A Synthetic Human Antibody Antagonizes IL-18Rβ Signaling Through an Allosteric Mechanism. J Mol Biol. 2020 Jan 15. pii: S0022-2836(20)30042-5. doi: 10.1016/j.jmb.2020.01.012. [Epub ahead of print]

12. Huang R, Sheng Y, Wei D, Yu J, Chen H, Jiang B.（2020）Bis(vinylsulfonyl)piperazines as efficient linkers for highly homogeneous antibody-drug conjugates. Eur J Med Chem. 2020 Jan 22;190:112080. doi: 10.1016/j.ejmech.2020.112080. [Epub ahead of print]

13. Hou W, Liu B, Xu H.（2020）Celastrol: Progresses in structure-modifications, structure-activity relationships, pharmacology and toxicology. Eur J Med Chem. 2020 Mar 1;189:112081. doi: 10.1016/j.ejmech.2020.112081. Epub 2020 Jan 20. Review

14. Wang L#, Wu J#, Li J#, Yang H, Tang T, Liang H, Zuo M, Wang J, Liu H, Liu F, Chen J, Liu Z, Wang Y, Peng C, Wu X, Zheng R, Huang X, Ran Y, Rao Z*, Ge B* (2020) Host-mediated ubiquitination of a mycobacterial protein suppresses immunity. Nature. 2020 Jan;577(7792):682-688. doi: 10.1038/s41586-019-1915-7. Epub 2020 Jan 15.

2019

1. Zhang B#, Li J#*, Yang X, Wu L, Zhang J, Yang Y, Zhao Y, Zhang L, Yang X, Yang X, Cheng X, Liu Z, Jiang B, Jiang H, Guddat LW, Yang H*, Rao Z*. Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell. 2019 Jan 24. ISSN: 0092-8674;

2. 201. Structural analysis of fungal CENP-H/I/K homologs reveals a conserved assembly mechanism underlying proper chromosome alignment. Nucleic Acids Research. 2019 Jan 10. ISSN:0305-1048;    

3. Lu, Xiaoyun#;  Liu, Yuwan#;  Yang, Yiqun#;  Wang, Shanshan#;  Wang, Qian;  Wang, Xiya;  Yan, Zhihui;  Cheng, Jian;  Liu, Cui;  Yang, Xue;  Luo, Hao;  Yang, Sheng;  Gou, Junran;  Ye, Luzhen;  Lu, Lina;  Zhang, Zhidan;  Guo, Yu;  Nie, Yan;  Lin, Jianping;  Li, Sheng;  Tian, Chaoguang;  Cai, Tao;  Zhuo, Bingzhao;  Ma, Hongwu;  Wang, Wen;  Ma, Yanhe;  Liu, Yongjun*;  Li, Yin*;  Jiang, Huifeng*. Constructing a synthetic pathway for acetylcoenzyme A from one-carbon through enzyme design. Nature Communications. 2019 Mar 26. ISSN:2041-1723;  

4. Wang Xinyu#; Pu Jiahua#; Liu Yi; Ba Fang; Cui Mengkui; Li Ke; Xie Yu; Nie Yan; Mi Qixi; Li Tao; Liu Lingli; Zhu Manzhou; Zhong Chao*. Immobilization of functional nano-objects in living engineered bacterial biofilms for catalytic applications. National Science Review. 2019 Jul 30. ISSN:2053-714X;    

5. Wang, Yannan#;  Zhang, Fan;  Nie, Yan*;  Shang, Guijun*;  Zhang, Heqiao*. Structural analysis of Shigella flexneri bi-functional enzyme HisIE in histidine biosynthesis. Biochemical and Biophysical Research Communications. 2019 Aug 20. ISSN:0006-291X;    

6. El Khattabi, Laila#;  Zhao, Haiyan#;  Kalchschmidt, Jens#;  Young, Natalie#;  Jung, Seolkyoung;  Van Blerkom, Peter;  Kieffer-Kwon, Philippe;  Kieffer-Kwon, Kyong-Rim;  Park, Solji;  Wang, Xiang;  Krebs, Jordan;  Tripathi, Subhash;  Sakabe, Noboru;  Sobreira, Debora R.;  Huang, Su-Chen;  Rao, Suhas S. P.;  Pruett, Nathanael;  Chauss, Daniel;  Sadler, Erica;  Lopez, Andrea;  Nobrega, Marcelo A.;  Aiden, Erez Lieberman;  Asturias, Francisco J.*;  Casellas, Rafael*. A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers. Cell. 2019 Aug 22. ISSN:0092-8674;   

7. Zhang, Yu#; Zhang, Xuefei#; Ba, Zhaoqing; Liang, Zhuoyi; Dring, Edward W.; Hu, Hongli; Lou, Jiangman; Kyritsis, Nia; Zurita, Jeffrey; Shamim, Muhammad S.; Aiden, Aviva Presser; Aiden, Erez Lieberman; Alt, Frederick W*. The fundamental role of chromatin loop extrusion in physiological V(D)J recombination. Nature. 2019 Sep 11. ISSN:0028-0836;  

8. Qiu, Xing#; Sun, Ning#; Kong, Ying; Li, Yan; Yang, Xiaobao*; Jiang, Biao* . Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Organic Letters. 2019 May 8. ISSN:1523-7060;  

9. Zhao, Quanju1#; Ren, Chaowei#; Liu, Linyi#; Chen, Jinju; Shao, Yubao; Sun, Ning; Sun, Renhong; Kong, Ying; Ding, Xinyu; Zhang, Xianfang; Xu, Youwei; Yang, Bei; Yin, Qianqian*; Yang, Xiaobao*; Jiang, Biao*. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. Journal of Medicinal Chemistry. 2019 Oct 2. ISSN:0022-2623;  

10. Rong Huang, Zhihong Li, Jianghui Yu, Hongli Chen,* and Biao Jiang*. H2O‑Regulated Chemoselectivity in Oxa-Versus Aza-Michael Reactions. Organic Letters. 2019 May 16. ISSN:1523-7060 ;  

11. Rong Huang,# Wei Zhu,# Yue Wu,# Jiakang Chen, Jianghui Yu, Biao Jiang,* Hongli Chen * and Wenzhang Chen*. A novel mass spectrometry-cleavable, phosphatebased enrichable and multi-targeting protein cross-linker. Chemical Science. 2019 May 23. ISSN:1452-3981;  

12. Zhenzhen Yang#, Eric K. Wafula, Gunjune Kim, Saima Shahid, Joel R. McNeal, Paula E. Ralph, Prakash R. Timilsena, Wen-bin Yu, Elizabeth A. Kelly, Huiting Zhang, Thomas Nate Person, Naomi S. Altman, Michael J. Axtell, James H. Westwood & Claude W. dePamphilis* . Convergent horizontal gene transfer and cross-talk of mobile nucleic acids in parasitic plants. Nature plants. 2019 Jul 22. ISSN:2055026X;  

13. Gagliano O#, Luni C#, Qin W, Bertin E, Torchio E, Galvanin S, Urciuolo A, Elvassore N*.. Microfluidic reprogramming to pluripotency of human somatic cells. Nat Prot. 2019. ISSN:1745-2473;  

14. Martewicz S#, Luni C#, Serena E, Pavan P, Chen VH-S, Rampazzo A, Elvassore N*.. Transcriptomic characterization of a human in vitro model of arrhythmogenic cardiomyopathy under topological and mechanical stimuli. Ann Biomed Eng. 2019. ISSN:0090-6964 (Print) 1573-9686 (Online);  

15. Giobbe GG#, Crowley C#, Luni C#, Campinoti S, Khedr M, Kretzschmar K, De Santis MM, Zambaiti E, Hu Q, Michielin F, Meran L, Urbani L, Manfredi A, van Son G, Eaton S, Cacchiarelli D, Li VSW, Clevers H, Bonfanti P, Elvassore N*, De Coppi P*. Extracellular matrix hydrogel derived from decellularized tissues enables endoderm organoid culture. Nat Commun. 2019 (in press). ISSN:2041-1723;  

16. Wang Chen#, Yang Zhenzhen, Guo Fanghao, Shi Shuo, Han Xiaoshuai, Zeng An, Lin Haifan*, Jing Qing*. Heat shock protein DNAJA1 stabilizes PIWI proteins to support regeneration and homeostasis of planarian Schmidtea mediterranea. J Biol Chem. 2019 Jun 21. ISSN:0021-9258;  

17. Xinying Xue#, Chen Wang#, Zhiqiang Xue#, Jiaxin Wen,Jun Han, Xidong Ma, Xuelei Zang, Hui Deng, Rui Guo, Idorenyin Polycarp Asuquo, Chong Qin, Haijiao Wang, Quansheng Gao*, Sanhong Liu*, Jianxin Wang*. Exosomal miRNA profiling before and after surgery revealed potential diagnostic and prognostic markers for lung adenocarcinoma. Acta Biochimica et Biophysica Sinica. 2019 Nov 15. ISSN:1672-9145;  

18. Tonon F#, Giobbe GG#, Zambon A, Luni C, Gagliano O, Floreani A, Grassi G, Elvassore N*. In vitro metabolic zonation through oxygen gradient on a chip. Sci Rep. 2019. ISSN:2045-2322;  

19. Zoso A#, Zambon A#, Gagliano O, Giulitti S, Prevedello L, Fadini GP, Luni C, Elvassore N*.. Cross-talk of healthy and impaired human tissues for dissection of disease pathogenesis. Biotechnol Progr. 2019. ISSN:8756-7938 (print) 1520-6033 (Online);  

20. Beninatto R#*, Barbera C, De Lucchi O, Borsato G, Serena E, Guarise C, Pavan M, Luni C, Martewicz S, Galesso D, Elvassore N*. Photocrosslinked hydrogels from coumarin derivatives of hyaluronic acid for tissue engineering applications. Mater Sci Eng C Mater Biol Appl. 2019. ISSN:0928-4931;  

21. Wang M#, Guo X#, Yang X, Zhang B, Ren J, Liu A, Ran Y, Yan B, Chen F, Guddat LW, Hu J*, Li J* and Rao Z. Mycobacterial dynamin-like protein IniA mediates membrane fission. . Nat Commun. 2019 Aug 29. ISSN:2041-1723;

22. Wang S#, Zhou K, Yang X, Zhang B, Zhao Y, Xiao Y, Yang X, Yang H, Guddat LW, Li J, Rao Z. LW, Li J*, Rao Z*. Structural insights into substrate recognition by the type VII secretion system..Protein & Cell. . 2019 Nov 23. ISSN:1674-8018;  

23. Wang N#, Zhao D#, Wang J#, Zhang Y#, Wang M, Gao Y, Li F, Wang J, Bu Z*, Rao Z*, Wang X*. Architecture of African swine fever virus and implications for viral assembly. Science. 2019 Nov 1. ISSN:0033-3131;  

24. Xia S#, Yan L#, Xu W, Agrawal AS, Algaissi A, Tseng CK, Wang Q, Du L, Tan W, Wilson IA*, Jiang S*, Yang B*, Lu L*. A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Science Advances. 2019 Apr 10. ISSN:2375-2548;  

25. Pang X#, Tong Y, Xue W, Yang Y-F, Chen X, Liu J*, Chen D*. Expression and characterization of recombinant human lactoferrin in edible alga Chlamydomonas reinhardtii. Bioscience, Biotechnology, and Biochemistry. 2019 Jan 23. ISSN:0916-8451;  

26. Li B#, Zhou X-H# Yang P-Y, Zhu L, Zhong Y, Cai Z, Jiang B, Cai X, Liu J*, Jiang X*. Photoactivatable Fluorogenic Labeling via Turn-On Click-Like Nitroso-Diene Bioorthogonal Reaction. Advanced Science. 2019 May 2. ISSN:2198-3844;  

27. Pang X#, Tong Y, Li F, Wei X, Chen X*, Liu J*, Chen D*. Expression and characterization of human lactoferrin with tandem zinc finger protein in Chlamydomonas reinhardtii. Algal Research. 2019 Nov. ISSN:2211-9264;  

28. Li L#, Ngo HTT, Hwang E, Wei X, Liu Y, Liu J*, Yi T-H*. Conditioned medium from human adipose-derived mesenchymal stem cell culture prevents UVB-induced skin aging in human keratinocytes and dermal fibroblasts. International Journal of Molecular Sciences. In press. ISSN:1422-0067;  

29. Bian Hu#, Yan Zou, Linlin Zhang, Jiaxing Tang, Gabriele Niedermann, Elke Firat, Xingxu Huang*, and Xuekai Zhu*. Nucleofection with Plasmid DNA for CRISPR/Cas9-Mediated Inactivation of Programmed Cell Death Protein 1 in CD133-Specific CAR T Cells. Human Gene Therapy. 2019 Apr 10. ISSN:1557-7422;   

30. Qinan Yin#, Jiaxing Tang, Xuekai Zhu*. Next-generation sequencing technologies accelerate advances in T-cell therapy for cancer. Briefings in Functional Genomics. 2019 Mar 22. ISSN:2041-2657;  

31. Shi X#, Xiao Z#, Zonta F, Wang W, Wan Y, Li Y, Wang N, Kuang Y, Du M, Dong J, Wang J, Yang G*. Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte. Stem Cells. 2019 Feb 28. ISSN:1066-5099;  

32. Ma P#, Xu H#, Li J#, Lu F, Ma F, Wang S, Xiong H, Wang W, Buratto D, Zonta F, Wang N, Liu K, Hua T, Zhi-jie Liu, Yang G*, Lerner RA*. Functionality independent DNA encoding of complex natural products. Angew Chem Int Ed Engl. 2019 May 22. ISSN:1433-7851;  

33. Liu Y, Zhang J, Wang R, Wu Y, Wang W, Xin X, Du M, Cao Y, Zhang H*. Identification of novel Kv1.3 targeting venom peptides by a single round of autocrine-based selection. Biochem Biophys Res Commun. 2019 Jan 14. ISSN:0006-291X;  

34. Yang YQ, Liang J, Han XD, Tian RM, Liu XS, Mao W, Xu HT*, Liu B*, Xu P*. Dual-function of triptriolide in podocytes injury: inhibiting of apoptosis and restoring of survival. Biomed Pharmacother. 2019 Jan 14. ISSN:0753-3322;  

35. Lu Y, Yan JS, Xia L, Qin K, Yin QQ, Xu HT, Gao MQ, Qu XN, Sun YT, Chen GQ. 2-Bromopalmitate targets retinoic acid receptor alpha and overcomes all-trans retinoic acid resistance of acute promyelocytic leukemia. Haematologica. 2019 Aug 3. ISSN:0390-6078;  

36. Ziraldo G, Buratto D, Kuang Y, Xu L, Carrer A, Nardin C, Chiani F, Salvatore AM, Paludetti G, Lerner RA, Yang G, Zonta F, Mammano F*. A human-derived monoclonal antibody targeting extracellular connexin domain selectively modulates hemichannel function. Frontiers in Physiology. 2019 Jun 11. ISSN:1664-042X;  

37. H. Xu*, B. Liu*. Triptolide-targeted delivery methods. Eur. J. Med. Chem. 2019 Feb 15. ISSN:0223-5234;  

38. W. Hou, G. Zhang, Z. Luo, L. Su*, H. Xu*. Click chemistry‐based synthesis and cytotoxic activity evaluation of 4α‐triazole acetate podophyllotoxin derivatives. Chem. Biol. Drug Des. 2019 Nov 28. ISSN:1747-0277;  

39. Yang Z, Wan Y, Tao P, Qiang M, Dong X, Lin CW, Yang G, Zheng T*, Lerner RA*. A cell-cell interaction format for selection of high-affinity antibodies to membrane proteins. Proc Natl Acad Sci U S A. 2019 Jul 23. ISSN:0027-8424;  

40. Xu H#.Ma F#.Wang N.Hou W.Xiong H.Lu F, Li J.Wang S.Ma P.Yang G*.Lerner RA*.. DNA-Encoded Libraries: Aryl Fluorosulfonates as Versatile Electrophiles Enabling Facile On-DNA Suzuki, Sonogashira, and Buchwald Reactions. Advance Science. 2019 Sep 30. ISSN:2198-3844;  

41. Zhang S, Xiong H, Lu F, Ma F, Gu Y, Ma P*, Xu H*, Yang G*. Synthesis of N-Acyl Sulfamates from Fluorosulfonates and Potassium Trimethylsilyloxyl Imidates. J Org Chem. 2019 Nov 12. ISSN:0022-3263;  

42. W. Hou, B. Liu*, H. Xu*. Triptolide: medicinal chemistry, chemical biology and clinical progress. Eur. J. Med. Chem. 2019 May 13. ISSN:0223-5234;  

43. W. Hou, H. Xiong, R. Bai, Z. Xiao, L. Su, B.H. Ruan*, H. Xu*. Synthesis of Indazolo[2,1-a]Cinnolines via Rhodium (III)-Catalyzed C–H activation/annulation under mild conditions. Tetrahedron. 2019 Jun 24. ISSN:0040-4020;  

44. X. Wang, R. Tian, Y. Yang, Z.-Y. Lu, X. Han, X. Liu, W. Mao, P. Xu*, H. Xu*, B. Liu*. Triptriolide antagonizes triptolide-induced nephrocyte apoptosis via inhibiting oxidative stress in vitro and in vivo. Biomed Pharmacother. 2019 Jul 15. ISSN:0753-3322;  

45. Nielsen BS#, Zonta F, T Farkas, T Litman, MS Nielsen, N MacAulay*. Structural determinants underlying permeant discrimination of the Cx43 hemichannel. Journal of Biological Chemistry. 2019 Nov 08. ISSN:1083-351X;  

46. Yang Zhang#, Xiaodan Sun#, Yangyang Qian, Hongfei Yi, Ke Song, Huanhu Zhu, Francesco Zonta, Weizhong Chen, Quanjiang Ji, Shane Miersch, Sachdev S Sidhu*, Donghui Wu*. A potent anti-SpuE antibody allosterically inhibits type III secretion system and attenuates virulence of Pseudomonas aeruginosa, Journal of molecular biology. 2019 Nov 02. ISSN:0022-2836;  

47. Gaia Ziraldo#, Damiano Buratto#, Yuanyuan Kuang, Liang Xu, Andrea Carrer, Chiara Nardin, Francesco Chiani, Anna Maria Salvatore, Gaetano Paludetti, Richard A Lerner, Guang Yang*, Francesco Zonta*, Fabio Mammano*. A human-derived monoclonal antibody targeting extracellular connexin domain selectively modulates hemichannel function. Frontiers in physiology. 2019 Jun 11. ISSN:1664-042X

48. Nielsen BS#, Zonta F, T Farkas, T Litman, MS Nielsen, N MacAulay*. Structural determinants underlying permeant discrimination of the Cx43 hemichannel. Journal of Biological Chemistry, 2019, 294 (45), 16789-16803

49. Yang Zhang#, Xiaodan Sun#, Yangyang Qian, Hongfei Yi, Ke Song, Huanhu Zhu, Francesco Zonta, Weizhong Chen, Quanjiang Ji, Shane Miersch, Sachdev S Sidhu*, Donghui Wu*. A potent anti-SpuE antibody allosterically inhibits type III secretion system and attenuates virulence of Pseudomonas aeruginosa. Journal of molecular biology, Volume 431, Issue 24, 6 December 2019, Pages 4882-4896

Giulitti S, Pellegrini M, Zorzan I, Martini P, Gagliano O, Mutarelli M, Ziller MJ, Cacchiarelli D, Romualdi C, Elvassore N, Martello G. 2018. Direct generation of human naive induced pluripotent stem cells from somatic cells in microfluidics. Nat Cell Biol. doi: 10.1038/s41556-018-0254-5.

Zoso A., Zambon A., Gagliano O., Giulitti S., Prevedello L., Fadini G.P., Luni C.,Elvassore N. (2018) Cross-talk of healthy and impaired human tissues for dissection of disease pathogenesis. Biotechnol Progr. doi: 10.1002/btpr.2766.

Martewicz S.*, Luni C.*, Serena E., Pavan P., Chen V. H.-S., Rampazzo A., Elvassore N. (2018) Transcriptomic characterization of a human in vitro model of arrhythmogenic cardiomyopathy under topological and mechanical stimuli. Ann Biomed Eng. doi: 10.1007/s10439-018-02134-8.

Prevedello L., Michielin F., Balcon M., Savio E., Pavan P., Elvassore N. (2018) A novel microfluidic platform for biomechano-stimulations on a chip. Ann Biomed Eng.<.em> doi: 10.1007/s10439-018-02121-z.

Dong, Y.; Rodrigues, M.; Kwon, S.H.; Li, X.; A, S.; Brett, E.A.; Elvassore, N.; Wang, W.; Gurtner, C.G.(2018) ‘Acceleration of diabetic wound regeneration using an in-situ-formed stem cell-based skin substitute’. Advanced Healthcare Materials, 7(17):e1800432. doi: 10.1002/adhm.201800432.

Hu Q., Luni C., Elvassore N. (2018) Microfluidics for secretome analysis under enhanced endogenous signaling. Biochem Bioph Res Co 497(2):480-484 doi: 10.1016/j.bbrc.2018.02.025.

Liu J*, Li J, Li J, Zhu L, Wang S-J, Wei X, Ma P-X* (2018) Delivery of superoxide dismutase using Cys2-His2 zinc-finger proteins. in Methods Mol Biol (Liu J Eds., Humana Press, Totowa) 1867, 113-123.

Liu J*, Liang Y-J, Ren P-L, Gaj T (2018) Manufacturing and delivering genome-editing proteins. in Methods Mol Biol (Liu J Eds., Humana Press, Totowa) 1867, 253-273.

ShanghaiTech Researchers Discover a New Electron Transfer Mechanism from a Mycobacterial Respiratory Supercomplex

Lab of stem cell biology reveals the mechanism of Wnt/β-catenin signaling pathway activation in triple negative breast cancer

Vicario, M., Zanni, G., Vallese, F., Santorelli, F., Grinzato, A., Cieri, D., Berto, F., Frizzarin, M., Lopreiato, R., Zonta, F., Ferro, S., Sandre, M, Marin, O., Ruzzene, M., Bertini, E., Zanotti, G., Brini, M., Calì, T., Carafoli, E., A V1143F mutation in the neuronal-enriched isoform 2 of the PMCA pump is linked with ataxia. Neurobiology of Disease, Volume 115, July 2018, Pages 157-166. doi: 10.1016/j.nbd.2018.04.009

Zonta,F., Buratto, D., Crispino, G., Carrer, A., Bruno, F., Yang, G.,Mammano, F.,* and Pantano, S.,*. Cues to Opening Mechanisms From in Silico Electric Field Excitation of Cx26 Hemichannel and in Vitro Mutagenesis Studies in HeLa Transfectans. Front. Mol. Neurosci., 31 May 2018. https://doi.org/10.3389/fnmol.2018.00170

Yang, Z., Du, M., Wang, W., Xin, X., Ma, P., Zhang, H., Lerner, R. A., Affinity maturation of an TpoR targeting antibody in full-length IgG form for enhanced agonist activity. Protein engineering, design & selection : PEDS 2018. https://doi.org/10.1093/protein/gzy002

Martewicz S, Gabrel G, Campesan M, Canton M, Di Lisa F, Elvassore N. Live Cell Imaging in Microfluidic Device Proves Resistance to Oxygen/Glucose Deprivation in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Anal Chem. 2018 Apr 9. doi: 10.1021/acs.analchem.7b05347.

Piao Z., Wang W., Wei Y., Zonta F., Wan C., Bai J., Wu S., Wang X., Fang J.*, Characterization of an acetohydroxy acid synthase mutant conferring tolerance to imidazolinone herbicides in rice (Oryza sativa). Planta, 2017 Nov 18. doi: 10.1007/s00425-017-2817-2

Martewicz S., Serena E., Zatti S., Keller g., Elvassore N., (2017) Substrate and mechanotransduction influence SERCA2a localization in human pluripotent stem cell-derived cardiomyocytes affecting functional performance. Stem Cell Research, Volume 25, December 2017, Pages 107-114, https://doi.org/10.1016/j.scr.2017.10.011

Crispino G., Galindo Ramirez F., Campioni M., Zorzi V., Praetorius M., Di Pasquale G., Chiorini J., Mammano F*., In vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors. Scientific Reports, 7(1): 6567. DOI: 10.1038/s41598-017-06759-y PMID: 28779115 IF: 4,259 (2016)

Zorzi V., Paciello F., Ziraldo G., Peres C., Mazzarda F., Nardin C., Pasquini M., Chiani F., Raspa M., Scavizzi F., Carrer A., Crispino G., Ciubotaru CD., Monyer H., Fetoni AR., Salvatore AM., Mammano F*., Mouse Panx1 is dispensable for hearing acquisition and auditory function. Frontiers in Molecular Neuroscience, 10, 298. Received: 02 Oct 2017; Accepted: 30 Oct 2017. In Press. DOI: doi: 10.3389/fnmol.2017.00379 IF: 5,076 (2016)

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