Research Assistant Professor
Laboratory: Lab of Stem Cell Biology
Email: wangchen@@shanghaitech.edu.cn
Biography:Ph.D. in Molecular Biology and Biochemistry
2010/09 – 2017/01 Laboratory of Nucleic Acid and Molecular Medicine
Institute for Health Sciences
Shanghai Jiao Tong University, Shanghai, China
B.S. in Biotechnology
2006/09 – 2010/07 College of Life Science
Northwest A&F University, Shanxi, China
Publications:
l Wang C, Lin H. Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs. Genome Biol. 2021 Jan 8;22(1):27. PMID: 33419460.
l Wang C, Yang ZZ, Guo FH, Shi S, Han XS, Zeng A, Lin H, Jing Q. Heat shock protein DNAJA1 stabilizes PIWI proteins to support regeneration and homeostasis of planarian Schmidtea mediterranea. J Biol Chem. 2019 Jun 21;294(25):9873-9887. PMID: 31076507.
l Wang C, Jing Q. Non-coding RNAs as biomarkers for acute myocardial infarction. Acta Pharmacol Sin. 2018 Jul;39(7):1110-1119. PMID: 29698386.
l Wang C, Han XS, Li FF, Huang S, Qin YW, Zhao XX, Jing Q. Forkhead containing transcription factor Albino controls tetrapyrrole-based body pigmentation in planarian. Cell Discov. 2016;2:16029. PMID: 27551436.
l Chen X*, Wang C*, Jiang Y, Wang Q, Tao Y, Zhang H, Zhao Y, Hu Y, Li C, Ye D, Liu D, Jiang W, Chin EY, Chen S, Liu Y, Wang M, Liu S, Zhang X. Bcl-3 promotes Wnt signaling by maintaining the acetylation of β-catenin at lysine 49 in colorectal cancer. Signal Transduct Target Ther. 2020 May 1;5(1):52. PMID: 32355204. (Co-1st author, cover story)
l Xue XY*, Liu YX*, Wang C*, Gu XJ*, Xue ZQ, Zang XL, Ma XD, Deng H, Liu R, Pan L, Liu SH. Identification of exosomal miRNAs as diagnostic biomarkers for cholangiocarcinoma and gallbladder carcinoma. Signal Transduct Target Ther. 2020 Jun 12;5(1):77. PMID: 32527999. (Co-1st author)
l Gu X*, Wang C*, Deng H, Qing C, Liu R, Liu S, Xue X. Exosomal piRNA profiling revealed unique circulating piRNA signatures of cholangiocarcinoma and gallbladder carcinoma. Acta Biochim Biophys Sin (Shanghai). 2020 May 26;52(5):475-484. PMID: 32369104. (Co-1st author)
l Xue X*, Wang C*, Xue Z, Wen J, Han J, Ma X, Zang X, Deng H, Guo R, Asuquo IP, Qin C, Wang H, Gao Q, Liu S, Wang J. Exosomal miRNA profiling before and after surgery revealed potential diagnostic and prognostic markers for lung adenocarcinoma. Acta Biochim Biophys Sin (Shanghai). 2020 Mar 18;52(3):281-293. PMID: 32073597. (Co-1st author)
l Chen X*, Wang C*, Liao K, Zhou S, Cao L, Chen J, Xu C, Lin Y. USP17 Suppresses Tumorigenesis and Tumor Growth through Deubiquitinating AEP. Int J Biol Sci. 2019;15(4):738-748. PMID: 30906206. (Co-1st author)
l Han XS, Wang C, Guo FH, Huang S, Qin YW, Zhao XX, Jing Q. Neoblast-enriched zinc finger protein FIR1 triggers local proliferation during planarian regeneration. Protein Cell. 2019 Jan;10(1):43-59. PMID: 29557542.
l Qiu XX, Liu Y, Zhang YF, Guan YN, Jia QQ, Wang C, Liang H, Li YQ, Yang HT, Qin YW, Huang S, Zhao XX, Jing Q. Rapamycin and CHIR99021 Coordinate Robust Cardiomyocyte Differentiation From Human Pluripotent Stem Cells Via Reducing p53-Dependent Apoptosis. J Am Heart Assoc. 2017 Oct 2;6(10). PMID: 28971953.
l Chen J, Zhu RF, Li FF, Liang YL, Wang C, Qin YW, Huang S, Zhao XX, Jing Q. MicroRNA-126a Directs Lymphangiogenesis Through Interacting With Chemokine and Flt4 Signaling in Zebrafish. Arterioscler Thromb Vasc Biol. 2016 Dec;36(12):2381-2393. PMID: 27789478.
l Zeng A, Li YQ, Wang C, Han XS, Li G, Wang JY, Li DS, Qin YW, Shi Y, Brewer G, Jing Q. Heterochromatin protein 1 promotes self-renewal and triggers regenerative proliferation in adult stem cells. J Cell Biol. 2013 Apr 29;201(3):409-25. PMID: 23629965.
l Qi MY, Wang ZZ, Zhang Z, Shao Q, Zeng A, Li XQ, Li WQ, Wang C, Tian FJ, Li Q, Zou J, Qin YW, Brewer G, Huang S, Jing Q. AU-rich-element-dependent translation repression requires the cooperation of tristetraprolin and RCK/P54. Mol Cell Biol. 2012 Mar;32(5):913-28. PMID: 22203041.
l Li YQ, Zeng A, Han XS, Wang C, Li G, Zhang ZC, Wang JY, Qin YW, Jing Q. Argonaute-2 regulates the proliferation of adult stem cells in planarian. Cell Res. 2011 Dec;21(12):1750-4. PMID: 21894189.
