王瑛 博士

发布者:冯明静发布时间:2019-11-14浏览次数:98


  王瑛 博士


助理研究员
邮箱:wangying1@@shanghaitech.edu.cn
电话:021-20654501
地址:上海科技大学人字楼B502

研究方向:干细胞与神经退行性疾病

工作经历

2019/04--至今:上海科技大学,免疫化学研究所,助理研究员

2018/04--2019/03:复旦大学,生物医学院,助理研究员

2016/06--2018/03:上海东方医院干细胞中心,干细胞制备与质检平台,干细胞质检组长

2015/08--2016/05:绿谷制药有限公司,绿谷研究院科学家 II

2013/07--2015/08:瑞金医院,神经病学研究所,博士后

2009/03--2013/03:中国科学院上海生命科学研究院生物化学与细胞生物学研究所,细胞信号转导研究组,研究助理

2008/07--2010/06:中国科学院上海生命科学研究院/上海交通大学医学院,健康科学研究所,研究助理

教育经历

2010/09--2013/06:上海交通大学医学院,神经病学,博士

2005/09--2008/06:中南大学湘雅医学院医学遗传学国家重点实验室,医学遗传学,硕士

2001/09--2005/06:中南大学湘雅医学院医学遗传学国家重点实验室,生物科学,学士


获资助项目:

1. 2018--2020,国家自然科学基金青年项目“神经免疫因子调控神经干细胞神经发生的机制及其干预阿尔茨海默病的可行性研究”(81701054) 项目负责

2. 2017--2021,国家重点研发计划干细胞及转化研究专项“细胞移植在治疗视网膜退行性疾病中的应用和机制研究”(2017YFA0104100) 学术骨干


专利:

赵简,丁健青,王瑛,一种用于早期诊断阿尔茨海默病的试剂盒,中国,ZL 2017 1 0081316.1。(已授权)


发表文章:

1. Ying Wang, Jing Zhang, Ying Lei*, Jian Zhao*, Establishment of TUSMi007-A, an induced pluripotent stem cell (iPSC) line from an 83-year old Chinese Han patient with Alzheimer's disease (AD), Stem Cell Research, 2018, 33:265-268.

2. Ying Wang#, Hongxiang Yu#, Ying Chen, Gang Li, Ying Lei*, Jian Zhao*, Derivation of induced pluripotent stem cells TUSMi006 from an 87-year old Chinese Han Alzheimer's disease patient carrying GRINB and SORL1 mutations, Stem Cell Research, 2018, 31:127-130.

3. Ying Wang#, Qiang Fen#, Hongxiang Yua, Haixia Qiue, Xiquan Ma*, Ying Lei*, Jian Zhao* Establishment of TUSMi005-A, an induced pluripotent stem cell (iPSC) line from a 32-year old Chinese Han patient with Bipolar Disorder (BD), Stem Cell Research, 2018, 33: 65-68.

4. Ying Wang#, Chuanyuan Kang#, Hongxiang Yu, Jing Fen, Xiquan Ma*, Ying Lei*, Jian Zhao*, Establishment of TUSMi004-A, an induced pluripotent stem cell (iPSC) line from a 32-year old Chinese Han patient with Obsessive-Compulsive Disorder (OCD), Stem Cell Research, 2018, 32: 83-86.

5. Ying Wang#, Hongxiang Yu#, Yue Zhang, Jing Zhang, Keni Chen, Heng Sun, Shulin Meng, Gang Li*,Ying Lei*, Jian Zhao, Establishment of TUSMi003-A, an induced pluripotent stem cell (iPSC) line from a 62-year old Chinese Han patient with Alzheimer's disease with ApoE3/4 genetic background, Stem Cell Research, 2018, 01:57-60.

6. Ying Wang#, Yue Zhang#, Jing Zhang, Jing Lu, Chaowen Yang, Jian Zhao, Gang Li, Zhongmin Liu* and Ying Lei*, Generation of a human control PBMC derived iPS cell line TUSMi001-A from a healthy male donor of Han Chinese genetic background, Stem Cell Research, 2017, 25:22-25

7. Ying Wang#, Jing Zhang#Yue Zhang, Danyi Huang, Jian Zhao, Gang Li* and Ying Lei*, Generation of a human induced pluripotent stem cell line from a 65-year old healthy female donor with Chinese Han genetic background, Stem Cell Research, 2017, 24:33-35.

8. Wang Ying#, Wang Ying#, Sui Yi, Yu Hongshuang, Shen Xiaoheng, Chen Shengdi, Pei Gang Zhao Jian*, Ding Jianqing*, The combination of Aricept with a Traditional Chinese Medicine formula, Smart Soup, may be a novel way to treat Alzheimer’s disease. Journal of Alzheimer's Disease. 2015, 45(4):1185-95.

9. Yujun Hou#, Ying Wang#, Jian Zhao#*, Xiaohang Li,1 Jin Cui, Jianqing Ding, Ying Wang, Xianglu Zeng, Yun Ling, Xiaoheng Shen, Shengdi Chen, Chenggang Huang and Gang Pei*, Smart Soup, a Traditional Chinese Medicine Formula, ameliorates amyloid pathology and related cognitive deficits. PLoS One, 2014, 11;9(11) (co-first authorship)

10. Bei Zhang, Ying Wang, Hui Li, Ran Xiong, Zongbo Zhao,  Xingkun Chu, Qiongqiong Li, Suya Sun* and Shengdi Chen*, Neuroprotective effects of salidroside through PI3K/Akt pathway activation in Alzheimer's disease models. Drug Des Devel Ther. 2016,6;10:1335-43.

11. Zhiquan Wang, Jun Liu, Siyan Chen, Ying Wang, Shengdi Chen* & Jianqing Ding*, DJ-1 Modulates the Expression of Cu/Zn-Superoxide Dismutase-1 through theErk1/2–Elk1 Pathway in Neuroprotection. ANN NEUROL, 2011, 70(4):591-9.