助理研究员
生物工程学实验室
邮件: smartewicz@@shanghaitech.edu.cn 研究方向: Mechanobiology of the cell nucleus: molecular mechanisms of nuclear shape changes during differentiation of immune system cells and cancer cell in 3D environments. Stem cell cardiac differentiation and cardiac disease modeling with hPSCs.
个人简介: 2019-Present: Research Assistant Professor, SIAIS, ShanghaiTech University, Shanghai, China
2016-2019: Postdoctoral Researcher, SIAIS, ShanghaiTech University, Shanghai, China 2015-2016: Postdoctoral Researcher, University of Padua, Italy 2015 Ph.D. in Biosciences and Biotechnology, University of Padua, Italy 2014 Visiting PhD student, Sanford-Burnham Medical Research Institute, La Jolla, California, USA 2010-2011 Research assistant University of Padua, Italy
2010 M.Sc. in Industrial Biotechnology, University of Padua, Italy
2008 B.Sc. in Biotechnology, University of Padua, Italy
获奖: 2018 Excellent Employee Award, ShanghaiTech University, Shanghai, China 2012-2014 PhD Fellowship by Citta’ della Speranza Foundation, Padua, Italy 代表性论文: · Martewicz S*, Magnussen M, Elvassore N. “Beyond Family: modeling non-hereditary heart diseases with human pluripotent stem cell-derived cardiomyocytes” Frontiers in Physiology. 2020 doi: 10.3389/fphys.2020.00384 · Beninatto R, Barbera C, De Lucchi O, Borsato G, Serena E, Guarise C, Pavan M, Luni C, Martewicz S, Galesso D, Elvassore N. “Photocrosslinked hydrogels from coumarin derivatives of hyaluronic acid for tissue engineering applications” Materials Scince and Engineering C. 2019 doi:10.1016/j.msec.2018.11.052 · Martewicz S#, Luni C#, Serena E, Pavan P, Chen HSV, Rampazzo A, Elvassore N. “Transcriptomic characterization of a human in vitro model of arrhythmogenic cardiomyopathy under topological and mechanical stimuli” Annals of Biomedical Engineering, 2019 doi:10.1007/s10439-018-02134-8 · Martewicz S, Gabrel G, Campesan M, Canton M, DiLisa F, Elvassore N.
“Live cell imaging in microfluidic device proves resistance to oxygen/glucose deprivation in hiPS-CMs” Analytical Chemistry, 2018 doi:10.1021/acs.analchem.7b05347 · Martewicz S, Serena E, Zatti S, Keller G, Elvassore N.
“Substrate and mechanotransduction influence SERCA2a localization in human pluripotent stem cell-derived cardiomyocytes affecting functional performance” Stem Cell Research, 2017 doi:10.1016/j.scr.2017.10.011 · Grespan E, Martewicz S, Serena E, Le Houérou V, Ruehe J, Elvassore N. “Analysis of calcium dynamics and uni-axial contraction force in single human embryonic stem cell derived-cardiomyocytes on micro-structured elastic substrate with spatially controlled surface chemistries Langmuir, 2016 doi:10.1021/acs.langmuir.6b03138 · Giobbe G, Michielin F, Luni C, Giulitti S, Martewicz S, Dupont S, Floreani A, Elvassore N. “Functional differentiation of human pluripotent stem cells on a chip.” Nature Methods. 2015 doi:10.1038/nmeth.3411 · Zatti S, Martewicz S, Serena E, Uno N, Giobbe G, Kazuki Y, Oshimura M, Elvassore N. Complete restoration of multiple dystrophin isoforms in genetically corrected Duchenne Muscular Dystrophy patient-derived cardiomyocytesMolecular Therapy – Methods and Clinical Development, 2014 doi:10.1038/mtm.2013.1 · Martewicz S#, Michielin F#, Serena E, Zambon A, Mongillo M, Elvassore N. “Reversible alteration of calcium dynamics in cardiomyocytes during acute hypoxia transient in a microfluidic platform”. Integrative Biology (Camb). 2012 doi: 10.1039/c1ib00087j
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