助理研究员
所在学院 免疫化学研究所
研究方向 免疫化学生物学实验室
联系方式 wangyf2@@shanghaitech.edu.cn
主要研究内容
抗肿瘤新药研发，抗肿瘤耐药机制和联合用药策略的探究
代表性论文
1.Yafang Wang, Na Li, Xin Zhang, Tiffany Horng*. Mitochondrial metabolism regulates macrophage biology. J Biol Chem. 2021 Jul;297(1):100904
2.Yafang Wang#, Lei Yu#, Jian Ding 1*, and Yi Chen 1*. Iron Metabolism in Cancer. International Journal of Molecular Sciences. 2019, 20, 95
3.Xun Huang#, Juan Yan#, Min Zhang#, Yafang Wang#, Yi Chen, Xuhong Fu,Rongrui Wei, Xing-ling Zheng,Zhiwei Liu, Xiong Zhang, Hong Yang, Bingbing Hao,Yan-yan Shen, Yi Su,Xiaoji Cong, Min Huang, Minjia Tan,* Jian Ding,* Meiyu Geng*. Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-aberrant Solid Tumors. Cell, 2018. 08. 058
4.Jie Zhang#, Yafang Wang#, Yanyan Shen, Pengxing He, Jian Ding*, Yi Chen1*. G9a stimulates CRC growth by inducing p53 Lys373 dimethylation-dependent activation of Plk1.Theranostics. 2018; 8(10):2884-2895.
5.Yafang Wang, Jie Zhang, Yi Su, Yan-yan Shen, Dong-xian Jiang, Ying-yong Hou, Mei-yu Geng*, Jian Ding*, Yi Chen*. G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin. Nature Communications, volume 8, Article number: 274(2017)
