Postdoctoral research fellow
Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University
Email: mengbing@@shanghaitech.edu.cn
Tel: 021-20685590
Laboratory: Lab of Antibody Structure
Research Interest:
1) Structure-based bioengineering of Cas9 in CRISPR-Cas9 system (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeat; Cas, CRISPR associated sequences)
2) Gene therapy utilizing Cas9
Biography:
2007 B.S. of Natural ScienceSchool of Life Sciences, Xiamen University
2015 Ph.D.of BioinformaticsInstitute of Biophysics, Chinese Academy of Science
2016-present Postdoctoral research fellow Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China
Representative Publications:
1. Jiang Y, Jiang H, Zhou S, Meng B, Liu ZJ, Ouyang S. Crystal structure of hGEF-H1 PH domain provides insight into incapability in phosphoinositide binding. Biochem Biophys Res Commun. 2016;471(4):621-7.
2. Meng B, Wu D, Gu J, Ouyang S, Ding W, Liu ZJ. Structural and functional analyses of human tryptophan 2,3-dioxygenase. Proteins. 2014;82(11):3210-6.
3. Guo P, Zhao Z, Haak J, Wang S, Wu D, Meng B, Weitao T. Common mechanisms of DNA translocation motors in bacteria and viruses using one-way revolution mechanism without rotation. Biotechnol Adv. 2014;32(4):853-72.
