Principal Investigator, Assistant Professor
Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University
Email: yangbei@@shanghaitech.edu.cn
Tel: 021-20685590
Laboratory:Lab of Antibody Structure

Research Interest:
1) Complex interplay between host & microbes, and therapeutic vulnerability identification
2) Drug candidates discovery & optimization

Biography:
2004 B.S. National Talents Training Program, College of Life Sciences, Wuhan University
2010 Ph.D. of Biochemistry and Molecular Biology, Institute of Biochemistry and Cell Biology, Chinese Academy of Science
2010-2013 Visiting Fellow, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, U.S.
2013-2015 Postdoctoral Scholar, Department of Molecular and Cell Biology, University of California, Berkeley, U.S.
2015-present Research Associate Professor, Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China

Selected Awards and Honors:
2016 Shanghai Pujiang Talents Program
2017 National Science Fund for Young Scholars of China

Selected Publications: (* co-first author, # correspondence author)
1. Chen J#, Yang B#, Yang L#. (2019) Nat Biotechnol. 37(5):520-522
2. Xia S, Yan L, Xu W, Agrawal AS, Algaissi A, Tseng CK, Wang Q, Du L, Tan W, Wilson IA#, Jiang S#, Yang B#, Lu L#. (2019) Sci Adv. 5(4): eaav4580.
3. Yan L, Meng B, Xiang J, Wilson IA# & Yang B#. (2018) Acta Crystallographica Section D, 74(Pt 9):841-851
4. Wang X*, Li J*, Wang Y*, Yang B*, Wei J, Wu J, Wang R, Huang X#, Chen J#, Yang L#. (2018) Nature Biotechnology, 36(10):946-949
5. Qiang M, Dong X, Zha Z, Zuo XK, Song XL, Zhao LX, Yuan C, Huang C, Tao PD, Hu Q, Li WG, Hu WH, Li J, Nie Y, Buratto D, Zonta F, Ma PX, Yu Z, Liu LL, Zhang Y, Yang B, Xie J, Xu TL, Qu ZH, Yang G, Lerner RA. (2018) Proceedings of the National Academy of Sciences, 115(32): E7469-E7477
6. Li X*, Wang Y*, Liu Y*, Yang B*, Wang X, Wei J, Lu Z, Zhang Y, Wu J, Huang X#, Yang L#, Chen J#. (2018) Nature Biotechnology, 36(4):324-327.
7. Lei L*, Chen H*, Xue W*, Yang B*, Hu B*, Wei J, Wang L, Cui Y, Li W, Wang J, Yan L, Shang W, Gao J, Sha J, Zhuang M, Huang X, Shen B#, Yang L#, Chen J#. (2018) Nature Structural and Molecular Biology, 25(1):45-52.
8. Yang B#, Li X, Lei L, Chen J#. (2017) Journal of Genetics and Genomics, 44(9):423-437.
9. Wang L*, Xue W*, Yan L*, Li X, Wei J, Chen M, Wu J, Yang B#, Yang L#, Chen J#. (2017) Cell Research, 27(10):1289-1292.
10. Yang B, Stjepanovic G, Shen Q, Martin A, Hurley JH#. (2015) Nature Structural and Molecular Biology, 22(6):492-8.
11. Hurley JH#, Yang B. (2014) The Journal of Molecular Biology, 426(3):503-6.
12. Yang B, Zhong C, Peng Y, Lai Z, Ding J#. (2010) Cell Research, 20:1188-1200.
13. Dong X*, Yang B*, Li Y, Zhong C, Ding J#. (2009) The Journal of Biological Chemistry, 284:23754-23764.
14. Dong X*, Zhou M*, Zhong C, Yang B, Shen N, Ding J#. (2009) Nucleic Acids Research, 38:1401-1412.
15. Shen N, Zhou M, Yang B, Yu Y, Dong X, Ding J#. (2008) Nucleic Acids Research, 36:1288-1299.
16. Shen N*, Guo L*, Yang B, Jin Y and Ding J#. (2006) Nucleic Acids Research, 34:3246-3258.
17. Yang B*#, Zhuang Y, Shao XL. (2004) Journal of Wuhan Botanical Research, 22(2):183-186.