| | Haikun Liu, Ph.D. | Distinguished Adjunct Professor Principal Investigator Lab of Cancer Stem Cell Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University Email: liuhk1@@shanghaitech.edu.cn
Biography
2019~ Adjunct professor, SIAIS, ShanghaiTech 2015~ Head of Division of Molecular Neurogenetics, DKFZ 2011~2015 Head of Helmholtz University Young Investigator Group-Normal and neoplastic CNS stem cells, German Cancer Research Center (DKFZ), DKFZ-ZMBH alliance, D-69120, Heidelberg, Germany. 2005~2010 Postdoc with Prof. Günther. Schütz in the Dept. Molecular Biology of the Cell I, German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany. 2000~2005 Ph.D student, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200032. P.R.China. Ph.D granted on 30. July. 2005. 1996~2000 Shangdong Normal University.
Selected Publications Rusu,P., Shao, C., Neuerburg, A., Acikgöz, A.A., Wu, Y., Zou, P., Phapale, P., Shankar, TS., Döring, K., Dettling, S., Körkel-Qu, H., Bekki, G., Costa, B., Guo, T., Friesen, O., Schlotter, M., Heikenwalder, M., Tschaharganeh, DF., Bukan, B., Kramer, G., Angel, P., Herold-Mende, C., Radlwimmer, B., Liu, H-K. (2019) GPD1 specifically marks dormant glioma stem cells with a distinct metabolic profile. Cell Stem Cell. Venkataramani V, Tanev DI, Strahle C, Studier-Fischer A, Fankhauser L, Kessler T, Körber C, Kardorff M, Ratliff M, Xie R, Horstmann H, Messer M, Paik SP, Knabbe J, Sahm F, Kurz FT, Acikgöz AA, Herrmannsdörfer F, Agarwal A, Bergles DE, Chalmers A, Miletic H, Turcan S, Mawrin C, Hänggi D, Liu H-K, Wick W, Winkler F, Kuner T. (2019) Glutamatergic synaptic input to glioma cells drives brain tumour progression. Nature, 2019 Sep 18. doi: 10.1038/s41586-019-1564-x. Duman, C., Yaqubi, K., Hoffmann, A., Acikgöz, A.A., Korshunov, A., Bendszus, M., Herold-Mende, C., Liu, H.-K., and Alfonso, J. (2019). Acyl-CoA-Binding Protein Drives Glioblastoma Tumorigenesis by Sustaining Fatty Acid Oxidation. Cell Metabolism.https://doi.org/10.1016/j.cmet.2019.04.004 Feng, W., Kawauchi, D., Koekel-Qu, H., Deng, H., Serger, E., Sieber, L., Lieberman, JA., Jimeno-Gonzalez, S., Lambo, S., Hanna, B., Harim, Y., Jansen, M., Neuerburg, A., Friesen, O., Zuckermann, M., Rajendran,V., Gronych, J., Ayrault, O., Korshunov, A., Jones, D., Kool, M., Northcott, P., Lichter, P., Cortes-Ledesma, F., Pfister, SM., Liu H-K. (2017) The chromatin remodeler Chd7 is indispensable for mamalian brain development through activation of a neuronal differentiation program. Nature Communications.14758 (2017) Feng, W., Liu, H-K. (2017) Revealing the hidden powers that fuel adult neurogenesis. Cell Stem Cell. 20 (2), 154-156 Osswald, M., Jung, E., Sahm, F., Solecki, G., Venkataramani, V., Blaes, J., Weil, S., Horstmann, H., Wiestler, B., Syed, M., Huang, L., Ratliff, M., Karimian Jazi, K., Kurz, F. T., Schmenger, T., Lemke, D., Gommel, M., Pauli, M., Liao, Y., Haring, P., Pusch, S., Herl, V., Steinhauser, C., Krunic, D., Jarahian, M., Miletic, H., Berghoff, A. S., Griesbeck, O., Kalamakis, G., Garaschuk, O., Preusser, M., Weiss, S., Liu, H-K., Heiland, S., Platten, M., Huber, P. E., Kuner, T., von Deimling, A., Wick, W. and Winkler, F. (2015) Brain tumour cells interconnect to a functional and resistant network. Nature, 528, 93–98 Zhu, Z., Kahn, A., Weiler, M., Blaes. J, Jestaedt L., Geibert M., Zou P., Gronych J., Bernhardt, O., Korshunov, A., Bugner, V., Lichter, P., Radlwimmer, B., Heiland S., Bendszus, M., Wick, W., Liu, H-K*. (2014) Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival. Cell Stem Cell,15, 185-198 Feng, W., Kahn, A., Bellvis P., Zhu, Z., Bernhardt, O., Herold-Mende, C., Liu, H-K. (2013). The chromatin remodeler CHD7 regulates adult neurogenesis via activation of SoxC transcription factors. Cell Stem Cell, 13, 62–72
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