| | Xuekai Zhu , Ph.D. | Principal Investigator, Research Associate Professor, Lab of T Cell EngineeringAddress: Room 307, Building 6, No.99 Haike Road, Pudong District, Shanghai, ChinaEmail: zhuxk@@shanghaitech.edu.cn Research Interest: T cell engineering, cancer immunotherapy
 Education:Ph.D. in biochemistry and molecular biology, Institute of Microbiology,Chinese Academy of Sciences, Beijing, 2010M.Sc. in hydrobiology, Sun Yat-Sen University, Guangzhou, 2005B.Sc. in microbiology, Anhui University, Hefei, 2002Professional:2015-present, Associate Professor, Shanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University2015 (January-June) Postdoc, German Cancer Research Center (DKFZ)2011-2015 Postdoc, University Hospital Freiburg, Germany2010-2011 Postdoc, Institute of Microbiology, Chinese Academy of Sciences2005-2006 Research Assistant, Beijing Genomics InstitutePublications:1. Zhu, X. and Niedermann, G. (2015). Rapid and efficient transfer of the T cell agingmarker CD57 from glioblastoma stem cells to CAR T cells. Oncoscience 2,476-482.2. Zhu, X., Prasad, S., Gaedicke, S., Hettich, M., Firat, E., and Niedermann, G. (2015).Patient-derived glioblastoma stem cells are killed by CD133-specific CAR T cells but induce the T cell aging marker CD57. Oncotarget 6, 171-184.3. Gaedicke, S., Braun, F., Prasad, S., Machein, M., Firat, E., Hettich, M., Gudihal, R.,Zhu, X., Klingner, K., Schuler, J., Herold-Mende, C.C., Grosu, A.L., Behe, M., Weber, W., Macke, H., and Niedermann, G. (2014). Noninvasive positron emission tomography and fluorescence imaging of CD133+ tumor stem cells. Proc Natl Acad Sci U S A 111, E692-701.4. Zhang, G., Liu, R., Zhu, X., Wang, L., Ma, J., Han, H., Wang, X., He, W., Wang, W., Liu, C., Li, S., Sun, M., and Gao, B. (2013). Retargeting NK-92 for anti-melanoma activity by a TCR-like single-domain antibody. Immunol Cell Biol 91, 615-624.5. Wang, L., Liu, X., Zhu, X., Wang, W., Liu, C., Cui, H., Sun, M., and Gao, B. (2013). Generation of single-domain antibody multimers with three different self-associating peptides. Protein Eng Des Sel 26, 417-423.6. Zhu, X., Wang, L., Liu, R., Flutter, B., Li, S., Ding, J., Tao, H., Liu, C., Sun, M., and Gao, B. (2010). COMBODY: one-domain antibody multimer with improved avidity. Immunol Cell Biol 88, 667-675.7. Liu, C., Walter, T.S., Huang, P., Zhang, S., Zhu, X., Wu, Y., Wedderburn, L.R., Tang, P., Owens, R.J., Stuart, D.I., Ren, J., and Gao, B. (2010). Structural and functional insights of RANKL-RANK interaction and signaling. J Immunol 184, 6910-6919.8. Patents: Bin Gao, Rongzhi Liu and Xuekai Zhu (2010). Chimeric antibody and immune cell. CN Patent Application No. 201010033761.9 |
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