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Laboratories

  • Lab of Antibody Design
    • About Lab
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  • Lab of Antibody Chemistry
  • Lab of Phenotypic Screening
  • Lab of Structural biochemistry
  • Lab of Stem Cell Biology
  • Lab of Pathogenic Biology
  • Lab of Protein Machine and New...
  • Lab of Infection and Anti-infe...
  • Lab of Macromolecule Drug Deli...
  • Lab of Regenerative Medicine a...
  • Lab of Cell Calcium Signaling
  • Lab of Drug Design and Develop...
  • Lab of Immune Chemical Biology
  • Lab of Bioenergetics
  • Lab of Cancer Stem Cell
  • Lab of Anti-TB Structure
  • Lab of Membrane Protein Studie...
  • Lab of Translational Research ...
  • Lab of Viral Infection and Imm...
  • Lab of Viral Pathogenesis and ...
  • current location:首页  Laboratories  Lab of Antibody Design  Publications
  • Publications

1. Zhang H., Du M., Xie J., Liu X., Sun J., Wang W., Xin X., Possani L.D., Yea K., and Lerner R.A. (2016) Autocrine-Based Selection of Drugs that Target Ion Channels from Combinatorial Venom Peptide Libraries. Angew Chem Int Ed Engl doi: 10.1002/anie.201603052.


1. K Yea, Zhang H K, Xie J, Jones T M, Lin C W, Francesconi W, Berton F, Fallahi M, Sauer K and Lerner R A. Agonist antibody that induces human malignant cells to kill one another. Proceedings of the National Academy of Sciences of the United States of America 112, E6158-E6165, doi:10.1073/pnas.1519079112 (2015).


2. Yea K, Xie J, Zhang H, Zhang W, Lerner RA. ”Selection of multiple agonist antibodies from intracellular combinatorial libraries reveals that cellular receptors are functionally pleiotropic.” Curr Opin Chem Biol. 2015 Jan 23;26C:1-7. doi: 10.1016/j.cbpa.2015.01.002. [Epub ahead of print] Review.


3. Xie J, Yea K, Zhang H, Moldt B, He L, Zhu J, Lerner RA. ”Prevention of cell death by antibodies selected from intracellular combinatorial libraries.” Chem Biol. 2014 Feb 20;21(2):274-83. doi: 10.1016/j.chembiol.2013.12.006. Epub 2014 Jan 16.


4. Yea K, Zhang H, Xie J, Jones TM, Yang G, Song BD, Lerner RA. “Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections.” Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14966-71. doi: 10.1073/pnas.1313671110. Epub 2013 Aug 26.










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