Jia Chen

Technician, lab manager

E-mail: chenjia1@shanghaitech.edu.cn

Professional Experiences: 

2021.03 - present: Technician in Lab of Biological Engineering, SIAIS, ShanghaiTech University.

Education: 

2006-2010: College of Life Science, Sichuan Normal University, B.S. in Biotechnology          

 Representative Publications:

(*Corresponding author; #     Contributed equally)

1. Chen J, Huang D, Chen W, Guo C, Wei B, Wu C, Peng Z, Fan J, Hou Z, Fang Y, Wang Y, Kitazato   K, Yu G, Zou C, Qian C, Xiong S. Linker-extended native cyanovirin-N facilitates PEGylation and potently inhibits HIV-1 by targeting the glycan ligand. PLoS One. 2014 Jan 27;9(1):e86455.

2.  Lei Y, Chen W, Liang H, Wang Z, Chen J, Hong H, Xie L, Nie H, Xiong S. Preparation of a monoPEGylated derivative of cyanovirin-N and its virucidal effect on acyclovir-resistant strains of herpes simplex virus type 1. Arch Virol. 2019 May;164(5):1259-1269.

3. WuC, ChenW, ChenJ, HanB, PengZ, GeF, WeiB, LiuM, ZhangM, QianC, HouZ, LiuG, Guo C, Wang Y, Kitazato K, Yu G, Zou C, Xiong S. Preparation of monoPEGylated Cyanovirin-N's derivative and its anti-influenza A virus bioactivity in vitro and in vivo. J Biochem. 2015 Jun;157(6):539-48.

4. Xiang Y, Zheng K, Zhong M, Chen J, Wang Q, Wang Y. Ubiquitin-proteasome-dependent slingshot 1 downregulation in neuronal cells inactivates cofilin to facilitate HSV-1 replication. Virology. 2014 Jan 20;449:88-95.